| In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors P Zhang, RJ Zawadzki, M Goswami, PT Nguyen, V Yarov-Yarovoy, ... Proceedings of the National Academy of Sciences 114 (14), E2937-E2946, 2017 | 132 | 2017 |
| Structural basis for antiarrhythmic drug interactions with the human cardiac sodium channel PT Nguyen, KR DeMarco, I Vorobyov, CE Clancy, V Yarov-Yarovoy Proceedings of the National Academy of Sciences 116 (8), 2945-2954, 2019 | 99 | 2019 |
| Structural insights into TRPV2 activation by small molecules RA Pumroy, AD Protopopova, TC Fricke, IU Lange, FM Haug, PT Nguyen, ... Nature Communications 13 (1), 1-12, 2022 | 37 | 2022 |
| Towards Structure-Guided Development of Pain Therapeutics Targeting Voltage-Gated Sodium Channels PT Nguyen, V Yarov-Yarovoy Frontiers in pharmacology 13, 842032, 2022 | 29 | 2022 |
| Gain-of-function mutation of a voltage-gated sodium channel NaV1. 7 associated with peripheral pain and impaired limb development BS Tanaka, PT Nguyen, EY Zhou, Y Yang, V Yarov-Yarovoy, SD Dib-Hajj, ... Journal of Biological Chemistry 292 (22), 9262-9272, 2017 | 26 | 2017 |
| Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks J Koehler Leman, S Lyskov, SM Lewis, J Adolf-Bryfogle, RF Alford, ... Nature communications 12 (1), 1-15, 2021 | 17 | 2021 |
| Veratridine: A Janus-Faced Modulator of Voltage-Gated Sodium Ion Channels RA Craig, CE Garrison, PT Nguyen, V Yarov-Yarovoy, J Du Bois ACS Chemical Neuroscience, 2020 | 16 | 2020 |
| Computational design of peptides to target NaV1. 7 channel with high potency and selectivity for the treatment of pain PT Nguyen, HM Nguyen, KM Wagner, R Stewart, V Singh, P Thapa, ... Elife 11, e81727, 2022 | 15 | 2022 |
| Human cone elongation responses can be explained by photoactivated cone opsin and membrane swelling and osmotic response to phosphate produced by RGS9-catalyzed GTPase VP Pandiyan, PT Nguyen, EN Pugh Jr, R Sabesan Proceedings of the National Academy of Sciences 119 (39), e2202485119, 2022 | 14 | 2022 |
| Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation HA Ledford, S Park, D Muir, RL Woltz, L Ren, PT Nguyen, P Sirish, ... Journal of General Physiology 152 (12), 2020 | 12 | 2020 |
| A novel tarantula toxin stabilizes the deactivated voltage sensor of bacterial sodium channel C Tang, X Zhou, PT Nguyen, Y Zhang, Z Hu, C Zhang, V Yarov-Yarovoy, ... The FASEB Journal 31 (7), 3167-3178, 2017 | 9 | 2017 |
| Structural modeling of ion channels using AlphaFold2, RoseTTAFold2, and ESMFold PT Nguyen, BJ Harris, DL Mateos, AH González, AM Murray, ... Channels 18 (1), 2325032, 2024 | 7 | 2024 |
| An artificial intelligence accelerated virtual screening platform for drug discovery G Zhou, DV Rusnac, H Park, D Canzani, HM Nguyen, L Stewart, MF Bush, ... bioRxiv, 2024.03. 28.587262, 2024 | 7 | 2024 |
| Opening of capsaicin receptor TRPV1 is Stabilized Equally by Its Four Subunits S Li, PT Nguyen, S Vu, V Yarov-Yarovoy, J Zheng Journal of Biological Chemistry, 104828, 2023 | 5 | 2023 |
| Molecular determinants of μ-conotoxin KIIIA interaction with the human voltage-gated sodium channel NaV1. 7 IH Kimball, PT Nguyen, BM Olivera, JT Sack, V Yarov-Yarovoy Frontiers in Pharmacology 14, 2023 | 3 | 2023 |
| Assessing the Structural Basis of μ-Conotoxin KIIIA Inhibition of the Voltage-Gated Sodium Channel Nav1. 7 IH Kimball, PT Nguyen, JT Sack, V Yarov-Yarovoy Biophysical Journal 114 (3), 635a, 2018 | 3 | 2018 |
| Mapping the Nav1. 7 Channel Interaction with the Conotoxin KIIIA IH Kimball, PT Nguyen, JT Sack, V Yarov-Yarovoy Biophysical Journal 110 (3), 437a, 2016 | 2 | 2016 |
| Molecular Determinants of μ-Conotoxin KIIIA interaction with the Voltage-Gated Sodium Channel Nav1. 7 IH Kimball, PT Nguyen, BM Olivera, JT Sack, V Yarov-Yarovoy BioRxiv, 654889, 2019 | 1 | 2019 |
| Structural Modeling of Local Anesthetic and Antiarrhythmic Drug Binding to the Human Cardiac Voltage Gated Sodium Channel PT Nguyen, KR DeMarco, I Vorobyov, CE Clancy, V Yarov-Yarovoy Biophysical Journal 114 (3), 39a, 2018 | 1 | 2018 |
| An Open State Model of the Navab Channel Explored by Rosetta and Molecular Dynamics Simulation PT Nguyen, KR DeMarco, I Vorobyov, CE Clancy, TW Allen, ... Biophysical Journal 112 (3), 105a, 2017 | 1 | 2017 |
