| Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay A Narayanan, M Narwal, SA Majowicz, C Varricchio, SA Toner, ... Communications Biology 5 (1), 169, 2022 | 147 | 2022 |
| In vitro topical delivery of chlorhexidine to the cornea: Enhancement using drug-loaded contact lenses and β-cyclodextrin complexation, and the importance of simulating tear … MG Hewitt, PWJ Morrison, HM Boostrom, SR Morgan, M Fallon, PN Lewis, ... Molecular Pharmaceutics 17 (4), 1428-1441, 2020 | 27 | 2020 |
| Structure property relationships of N-acylsulfonamides and related bioisosteres KR Francisco, C Varricchio, TJ Paniak, MC Kozlowski, A Brancale, ... European journal of medicinal chemistry 218, 113399, 2021 | 25 | 2021 |
| Monoamine oxidase (MAO-N) biocatalyzed synthesis of indoles from indolines prepared via photocatalytic cyclization/arylative dearomatization F Zhao, D Masci, S Ferla, C Varricchio, A Brancale, S Colonna, GW Black, ... ACS Catalysis 10 (11), 6414-6421, 2020 | 24 | 2020 |
| Evaluation of the Structure–Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-a]pyrimidines Identifies New Candidates for Neurodegenerative … K Oukoloff, G Nzou, C Varricchio, B Lucero, T Alle, J Kovalevich, L Monti, ... Journal of medicinal chemistry 64 (2), 1073-1102, 2021 | 22 | 2021 |
| Focal drug administration via heparin-containing cryogel microcarriers reduces cancer growth and metastasis B Newland, C Varricchio, Y Körner, F Hoppe, C Taplan, H Newland, ... Carbohydrate polymers 245, 116504, 2020 | 19 | 2020 |
| The ying and yang of idebenone: Not too little, not too much–cell death in NQO1 deficient cells and the mouse retina C Varricchio, K Beirne, C Heard, B Newland, M Rozanowska, A Brancale, ... Free Radical Biology and Medicine 152, 551-560, 2020 | 18 | 2020 |
| Sulfonated cryogel scaffolds for focal delivery in ex-vivo brain tissue cultures D Eigel, R Schuster, MJ Männel, J Thiele, MJ Panasiuk, LC Andreae, ... Biomaterials 271, 120712, 2021 | 15 | 2021 |
| A novel dual action monolithic thermosetting hydrogel loaded with lidocaine and metronidazole as a potential treatment for alveolar osteitis L Bender, HM Boostrom, C Varricchio, M Zuanon, V Celiksoy, A Sloan, ... European Journal of Pharmaceutics and Biopharmaceutics 149, 85-94, 2020 | 15 | 2020 |
| Discovery of novel 2-aniline-1, 4-naphthoquinones as potential new drug treatment for Leber’s hereditary optic neuropathy (LHON) C Varricchio, K Beirne, P Aeschlimann, C Heard, M Rozanowska, ... Journal of Medicinal Chemistry 63 (22), 13638-13655, 2020 | 12 | 2020 |
| Biocatalytic and Chemo-Enzymatic Synthesis of Quinolines and 2-Quinolones by Monoamine Oxidase (MAO-N) and Horseradish Peroxidase (HRP) Biocatalysts H Xiang, S Ferla, C Varricchio, A Brancale, NL Brown, GW Black, ... ACS catalysis 13 (5), 3370-3378, 2023 | 11 | 2023 |
| Computational studies towards the identification of novel rhodopsin-binding compounds as chemical chaperones for misfolded opsins G Pasqualetto, M Schepelmann, C Varricchio, E Pileggi, C Khogali, ... Molecules 25 (21), 4904, 2020 | 11 | 2020 |
| Geneticin shows selective antiviral activity against SARS-CoV-2 by interfering with programmed− 1 ribosomal frameshifting C Varricchio, G Mathez, T Pillonel, C Bertelli, L Kaiser, C Tapparel, ... Antiviral Research 208, 105452, 2022 | 10 | 2022 |
| Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and … T Alle, C Varricchio, Y Yao, B Lucero, G Nzou, S Demuro, M Muench, ... Journal of Medicinal Chemistry 66 (1), 435-459, 2022 | 8 | 2022 |
| A composite system based upon hydroxypropyl cyclodextrins and soft hydrogel contact lenses for the delivery of therapeutic doses of econazole to the cornea, in vitro A Wong, M Fallon, V Celiksoy, S Ferla, C Varricchio, D Whitaker, ... Pharmaceutics 14 (8), 1631, 2022 | 7 | 2022 |
| PINK1-dependent mitophagy inhibits elevated ubiquitin phosphorylation caused by mitochondrial damage OA Lambourne, S Bell, LP Wilhelm, EB Yarbrough, GG Holly, OM Russell, ... Journal of Medicinal Chemistry 66 (11), 7645-7656, 2023 | 6 | 2023 |
| Ligand-based rational design, synthesis and evaluation of novel potential chemical chaperones for opsin G Pasqualetto, E Pileggi, M Schepelmann, C Varricchio, M Rozanowska, ... European Journal of Medicinal Chemistry 226, 113841, 2021 | 6 | 2021 |
| A time-kill assay study on the synergistic bactericidal activity of pomegranate rind extract and Zn (II) against Methicillin-resistant Staphylococcus aureus (MRSA … A Alrashidi, M Jafar, N Higgins, C Mulligan, C Varricchio, R Moseley, ... Biomolecules 11 (12), 1889, 2021 | 4 | 2021 |
| Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71 M Salerno, C Varricchio, F Bevilacqua, D Jochmans, J Neyts, A Brancale, ... European Journal of Medicinal Chemistry 246, 114942, 2023 | 3 | 2023 |
| Structure–Activity Relationship Studies on Novel Antiviral Agents for Norovirus Infections S Ferla, C Varricchio, W Knight, PK Ho, F Saporito, B Tropea, G Fagan, ... Microorganisms 9 (9), 1795, 2021 | 2 | 2021 |
