Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study DD Ferreira, JT Mesquita, TAC Silva, MM Romanelli, DGJ Batista, ... Journal of Venomous Animals and Toxins including Tropical Diseases 24, 30, 2018 | 24 | 2018 |
Sertraline delivered in phosphatidylserine liposomes is effective in an experimental model of visceral leishmaniasis MM Romanelli, TA Costa-Silva, E Cunha-Junior, D Dias Ferreira, ... Frontiers in cellular and infection microbiology 9, 353, 2019 | 19 | 2019 |
Antitrypanosomal activity of isololiolide isolated from the marine hydroid Macrorhynchia philippina (Cnidaria, Hydrozoa) ML Lima, MM Romanelli, SET Borborema, DM Johns, AE Migotto, ... Bioorganic chemistry 89, 103002, 2019 | 18 | 2019 |
Calanolides E1 and E2, two related coumarins from Calophyllum brasiliense Cambess.(Clusiaceae), displayed in vitro activity against amastigote forms of Trypanosoma cruzi and … LG Silva, KS Gomes, TA Costa-Silva, MM Romanelli, AG Tempone, ... Natural Product Research 35 (23), 5373-5377, 2021 | 17 | 2021 |
Antitrypanosomal Activity of Acetogenins Isolated from the Seeds of Porcelia macrocarpa Is Associated with Alterations in Both Plasma Membrane Electric Potential … EA Oliveira, IA Brito, ML Lima, M Romanelli, JT Moreira-Filho, BJ Neves, ... Journal of natural products 82 (5), 1177-1182, 2019 | 13 | 2019 |
Dereplication of Aporphine Alkaloids by UHPLC-HR-ESI-MS/MS and NMR from Duguetia lanceolata St. -Hil (Annonaceae) and Antiparasitic Activity Evaluation EP Dantas, J Monteiro, LS Medeiros, MM Romanelli, M Amaral, ... Journal of the Brazilian Chemical Society 31, 1908-1916, 2020 | 10 | 2020 |
Mitochondrial Imbalance of Trypanosoma cruzi Induced by the Marine Alkaloid 6-Bromo-2′-de-N-Methylaplysinopsin MM Romanelli, M Amaral, F Thevenard, LM Santa Cruz, LO Regasini, ... ACS omega 7 (32), 28561-28570, 2022 | 9 | 2022 |
Synthesis and Structure–Activity Relationship of Dehydrodieugenol B Neolignans against Trypanosoma cruzi CE Sear, P Pieper, M Amaral, MM Romanelli, TA Costa-Silva, ... ACS Infectious Diseases 6 (11), 2872-2878, 2020 | 9 | 2020 |
Hedyosulide, a novel trypanosomicidal sesterterpene lactone from Hedyosmum brasiliense Mart. ex Miq C Murakami, RSA Cabral, KS Gomes, TA Costa-Silva, M Amaral, ... Phytochemistry letters 33, 6-11, 2019 | 7 | 2019 |
A new reduced chalcone-derivative affects the membrane permeability and electric potential of multidrug-resistant Enterococcus faecalis AG Tempone, R dos Santos Theodoro, MM Romanelli, DAS Ferreira, ... Chemico-Biological Interactions 365, 110086, 2022 | 5 | 2022 |
Optimization of physicochemical properties is a strategy to improve drug-likeness associated with activity: Novel active and selective compounds against Trypanosoma cruzi MT Varela, M Amaral, MM Romanelli, EV de Castro Levatti, AG Tempone, ... European Journal of Pharmaceutical Sciences 171, 106114, 2022 | 5 | 2022 |
Repurposing topical triclosan for cutaneous leishmaniasis: Preclinical efficacy in a murine Leishmania (L.) amazonensis model JT Mesquita, MM Romanelli, C de Melo Trinconi Trinconi CM, JM Guerra, ... Drug Development Research 83 (2), 285-295, 2022 | 5 | 2022 |
Piperazine amides with desirable solubility, physicochemical and drug-like properties: Synthesis and evaluation of the anti-Trypanosoma cruzi activity MT Varela, M Romanelli, M Amaral, AG Tempone, JPS Fernandes Saudi Pharmaceutical Journal 31 (7), 1265-1273, 2023 | 2 | 2023 |
Antileishmanial Effects of Acetylene Acetogenins from Seeds of Porcelia macrocarpa (Warm.) R.E. Fries (Annonaceae) and Semisynthetic Derivatives IA Brito, F Thevenard, TA Costa-Silva, SS Oliveira, RLOR Cunha, ... Molecules 27 (3), 893, 2022 | 2 | 2022 |
Calanolides E1 and E2, two related coumarins fromCalophyllum brasiliense Cambess.(Clusiaceae), displayedin vitro activity against amastigote forms ofTrypanosoma cruzi … LG Silva, KS Gomes, TA Costa-Silva, MM Romanelli, AG Tempone, ... Natural Product Research, 2022 | | 2022 |
Atividade antimicrobiana do ácido (E)-masticadienoico, isolado das folhas de Schinus terebinthifolius (Anacardiaceae), frente à Neisseria gonorrhoeae E UMEHARA, M Romanelli, M Christodoulides, AG Tempone, JHG Lago Galoá, 2021 | | 2021 |
Dereplication of antileishmanial alkaloids from Duguetia lanceolata (Annonaceae) by LC-MS-MS JM Conceição, EP Dantas, LS Medeiros, P Sartorelli, MM Romanelli, ... | | |
Dereplication of antileishmanial active fraction and identification of new acetogenins from seeds of Porcelia macrocarpa (Annonaceae) EA Oliveira, DO Silva, P Sartorelli, M Romanelli, AG Tempone, ... | | |