The diverse roles of TNNI3K in cardiac disease and potential for treatment C Pham, N Muñoz-Martín, EM Lodder International journal of molecular sciences 22 (12), 6422, 2021 | 11 | 2021 |
Genetic Burden of TNNI3K in Diagnostic Testing of Patients With Dilated Cardiomyopathy and Supraventricular Arrhythmias C Pham, K Andrzejczyk, SJ Jurgens, R Lekanne Deprez, KCA Palm, ... Circulation: Genomic and Precision Medicine 16 (4), 328-336, 2023 | 2 | 2023 |
Reduced kinase function in two ultra‐rare TNNI3K variants in families with congenital junctional ectopic tachycardia C Pham, TT Koopmann, JM Vinocur, NA Blom, V Nogueira Silbiger, ... Clinical Genetics, 2024 | | 2024 |
PI3K/mTOR inhibitor omipalisib prolongs cardiac repolarization along with a mild proarrhythmic outcome in the AV block dog model JJA van Bavel, C Pham, HDM Beekman, MJC Houtman, A Bossu, ... Frontiers in cardiovascular medicine 9, 956538, 2022 | | 2022 |
TNNI3K delays atrioventricular conduction and reduces connexin-45 gap junctional coupling C Pham, S Podliesna, AO Verkerk, R Wolswinkel, N Muñoz-Martín, ... Europace 24 (Supplement_1), euac053. 621, 2022 | | 2022 |
Altered auto-phosphorylation of novel TNNI3K variants associated with AV-nodal re-entry tachycardia and conduction disease C Pham, N Munoz-Martin, S Podliesna, A Milano, L Beekman, A Vermeer, ... European Heart Journal 41 (Supplement_2), ehaa946. 0339, 2020 | | 2020 |
PI3K inhibition by omipalisib causes QT prolongation in the RVA-VDD paced AV-block dog model without an overt proarrhythmic risk JJA van Bavel, C Pham, HD Beekman, MJ Houtman, A Bossu, ... Journal of Pharmacological and Toxicological Methods 105, 106767, 2020 | | 2020 |