Autoantibodies against type I IFNs in patients with life-threatening COVID-19 P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ... Science 370 (6515), eabd4585, 2020 | 2452 | 2020 |
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 2138 | 2020 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 444 | 2021 |
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 332 | 2021 |
Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1 P Bastard, E Orlova, L Sozaeva, R Lévy, A James, MM Schmitt, S Ochoa, ... Journal of Experimental Medicine 218 (7), 2021 | 233 | 2021 |
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19 MGP van der Wijst, SE Vazquez, GC Hartoularos, P Bastard, T Grant, ... Science translational medicine 13 (612), eabh2624, 2021 | 172 | 2021 |
Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine P Bastard, E Michailidis, HH Hoffmann, M Chbihi, T Le Voyer, J Rosain, ... Journal of Experimental Medicine 218 (4), e20202486, 2021 | 144 | 2021 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 128 | 2022 |
JAK inhibitor therapy in a child with inherited USP18 deficiency F Alsohime, M Martin-Fernandez, MH Temsah, M Alabdulhafid, ... New England Journal of Medicine 382 (3), 256-265, 2020 | 75 | 2020 |
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children D Lee, J Le Pen, A Yatim, B Dong, Y Aquino, M Ogishi, R Pescarmona, ... Science 379 (6632), eabo3627, 2022 | 70 | 2022 |
JAK inhibitors are effective in a subset of patients with juvenile dermatomyositis: a monocentric retrospective study T Le Voyer, C Gitiaux, FJ Authier, C Bodemer, I Melki, P Quartier, ... Rheumatology 60 (12), 5801-5808, 2021 | 65 | 2021 |
Inherited deficiency of stress granule ZNFX1 in patients with monocytosis and mycobacterial disease T Le Voyer, AL Neehus, R Yang, M Ogishi, J Rosain, F Alroqi, M Alshalan, ... Proceedings of the National Academy of Sciences 118 (15), e2102804118, 2021 | 59 | 2021 |
Autoantibodies against type I IFNs in patients with critical influenza pneumonia Q Zhang, A Pizzorno, L Miorin, P Bastard, A Gervais, T Le Voyer, L Bizien, ... Journal of Experimental Medicine 219 (11), e20220514, 2022 | 47 | 2022 |
Lower disease activity but higher risk of severe COVID-19 and herpes zoster in patients with systemic lupus erythematosus with pre-existing autoantibodies neutralising IFN-α A Mathian, P Breillat, K Dorgham, P Bastard, C Charre, R Lhote, ... Annals of the rheumatic diseases 81 (12), 1695-1703, 2022 | 44 | 2022 |
Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs P Bastard, SE Vazquez, J Liu, MT Laurie, CY Wang, A Gervais, ... Science immunology 8 (90), eabp8966, 2023 | 42 | 2023 |
A partial form of inherited human USP18 deficiency underlies infection and inflammation M Martin-Fernandez, S Buta, T Le Voyer, Z Li, LT Dynesen, F Vuillier, ... Journal of Experimental Medicine 219 (4), e20211273, 2022 | 36 | 2022 |
Genetic, immunological, and clinical features of 32 patients with autosomal recessive STAT1 deficiency T Le Voyer, S Sakata, M Tsumura, T Khan, A Esteve-Sole, BK Al-Saud, ... The Journal of Immunology 207 (1), 133-152, 2021 | 35 | 2021 |
Inherited GATA2 deficiency is dominant by haploinsufficiency and displays incomplete clinical penetrance C Oleaga-Quintas, EB de Oliveira-Junior, J Rosain, F Rapaport, ... Journal of clinical immunology 41, 639-657, 2021 | 34 | 2021 |
Human IL-23 is essential for IFN-γ–dependent immunity to mycobacteria Q Philippot, M Ogishi, J Bohlen, J Puchan, AA Arias, T Nguyen, ... Science immunology 8 (80), eabq5204, 2023 | 32 | 2023 |
Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria J Rosain, AL Neehus, J Manry, R Yang, J Le Pen, W Daher, Z Liu, ... Cell 186 (3), 621-645. e33, 2023 | 32 | 2023 |