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Olwyn R. Mahon
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Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner
OR Mahon, DC Browe, T Gonzalez-Fernandez, P Pitacco, IT Whelan, ...
Biomaterials 239, 119833, 2020
2602020
Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues
GM Cunniffe, PJ Díaz-Payno, EJ Sheehy, SE Critchley, HV Almeida, ...
Biomaterials 188, 63-73, 2019
1102019
Harnessing the innate and adaptive immune system for tissue repair and regeneration: Considering more than macrophages
LC Shanley, OR Mahon, DJ Kelly, A Dunne
Acta Biomaterialia 133, 208-221, 2021
642021
Osteoarthritis-associated basic calcium phosphate crystals alter immune cell metabolism and promote M1 macrophage polarization
OR Mahon, DJ Kelly, GM McCarthy, A Dunne
Osteoarthritis and Cartilage 28 (5), 603-612, 2020
632020
Growth plate extracellular matrix-derived scaffolds for large bone defect healing.
GM Cunniffe, PJ Díaz-Payno, JS Ramey, OR Mahon, A Dunne, ...
Royal College of Surgeons in Ireland, 2017
492017
Orthopaedic implant materials drive M1 macrophage polarization in a spleen tyrosine kinase-and mitogen-activated protein kinase-dependent manner
OR Mahon, S O'Hanlon, CC Cunningham, GM McCarthy, C Hobbs, ...
Acta biomaterialia 65, 426-435, 2018
432018
Glyoxal cross‐linking of solubilized extracellular matrix to produce highly porous, elastic, and chondro‐permissive scaffolds for orthopedic tissue engineering
DC Browe, OR Mahon, PJ Díaz‐Payno, N Cassidy, I Dudurych, A Dunne, ...
Journal of Biomedical Materials Research Part A 107 (10), 2222-2234, 2019
352019
Disease-associated particulates and joint inflammation; mechanistic insights and potential therapeutic targets
OR Mahon, A Dunne
Frontiers in Immunology 9, 380087, 2018
232018
Extracellular matrix scaffolds derived from different musculoskeletal tissues drive distinct macrophage phenotypes and direct tissue-specific cellular differentiation
OR Mahon, DC Browe, PJ Diaz-Payno, P Pitacco, KT Cunningham, ...
Journal of Immunology and Regenerative Medicine 12, 100041, 2021
132021
S100A8 acts as an autocrine priming signal for heme-induced human pro-inflammatory responses in hemolytic inflammation
AAA Silveira, OR Mahon, CC Cunningham, EM Corr, R Mendonça, ...
Journal of leukocyte biology 106 (1), 35-43, 2019
122019
A spheroid model of early and late‐stage osteosarcoma mimicking the divergent relationship between tumor elimination and bone regeneration
FE Freeman, R Burdis, OR Mahon, DJ Kelly, N Artzi
Advanced Healthcare Materials 11 (7), 2101296, 2022
112022
Localized Nanoparticle‐Mediated Delivery of miR‐29b Normalizes the Dysregulation of Bone Homeostasis Caused by Osteosarcoma whilst Simultaneously Inhibiting Tumor Growth
FE Freeman, P Dosta, LC Shanley, N Ramirez Tamez, CJ Riojas Javelly, ...
Advanced Materials 35 (23), 2207877, 2023
92023
Macrophage metabolic profile is altered by hydroxyapatite particle size
LC Shanley, OR Mahon, SA O'Rourke, NGB Neto, MG Monaghan, ...
Acta Biomaterialia 160, 311-321, 2023
82023
Extracellular vesicle functionalized melt electrowritten scaffolds for bone tissue engineering
KF Eichholz, A Federici, M Riffault, I Woods, OR Mahon, L O’Driscoll, ...
Advanced NanoBiomed Research 1 (10), 2100037, 2021
82021
Generating an M2 pro‐regenerative macrophage phenotype using nanoHA particles for bone tissue engineering
O Mahon
European Cells and Materials 33, 2017
12017
Characterisation of Chronic Lymphocytic Leukaemia (CLL) immune profiles using single cell multi-omics
OR Mahon, C King, E Fennell, SE Hickey, PA Kiely, R Clifford, K McGourty
EUROPEAN JOURNAL OF IMMUNOLOGY 52, 70-70, 2022
2022
EXTRACELLULAR MATRIX SCAFFOLDS DERIVED FROM DIFFERENT MUSCULOSKELETAL TISSUES DRIVE DISTINCT MACROPHAGE PHENOTYPES AND DIRECT TISSUE-SPECIFIC CELLULAR DIFFERENTIATION
OR Mahon, DC Browe, P Pitacco, P Diaz-Payno, A Dunne, DJ Kelly
TISSUE ENGINEERING PART A 28, S540-S540, 2022
2022
Mechanically Activated Extracellular Vesicle Functionalised Melt Electrowritten Materials for Bone Regeneration: A Mechano-Biomimetic Scaffold
KF Eichholz, A Federici, M Riffault, I Woods, OR Mahon, L O’Driscoll, ...
bioRxiv, 2021.03. 29.437528, 2021
2021
Characterisation of the immune response to calcium phosphate particulates; implications for osteoarthritis and bone tissue engineering
O Mahon
Trinity College Dublin, 2020
2020
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Articles 1–19