Assessing toxicokinetic uncertainty and variability in risk prioritization JF Wambaugh, BA Wetmore, CL Ring, CI Nicolas, RG Pearce, GS Honda, ... Toxicological Sciences 172 (2), 235-251, 2019 | 75 | 2019 |
Comparison of in vitro to in vivo extrapolation approaches for predicting transporter-mediated hepatic uptake clearance using suspended rat hepatocytes N Li, A Badrinarayanan, X Li, J Roberts, M Hayashi, M Virk, A Gupta Drug Metabolism and Disposition 48 (10), 861-872, 2020 | 17 | 2020 |
Albumin-Mediated Uptake Improves Human Clearance Prediction for Hepatic Uptake Transporter Substrates Aiding a Mechanistic In Vitro-In Vivo Extrapolation … N Li, A Badrinarayanan, K Ishida, X Li, J Roberts, S Wang, M Hayashi, ... The AAPS Journal 23, 1-15, 2021 | 16 | 2021 |
P-glycoprotein substrate assessment in drug discovery: Application of modeling to bridge differential protein expression across in vitro tools N Li, P Kulkarni, A Badrinarayanan, A Kefelegn, R Manoukian, X Li, ... Journal of Pharmaceutical Sciences 110 (1), 325-337, 2021 | 5 | 2021 |