| A three-dimensional organoid culture system derived from human glioblastomas recapitulates the hypoxic gradients and cancer stem cell heterogeneity of tumors found in vivo CG Hubert, M Rivera, LC Spangler, Q Wu, SC Mack, BC Prager, M Couce, ... Cancer research 76 (8), 2465-2477, 2016 | 549 | 2016 |
| Cancer stem cells: the architects of the tumor ecosystem BC Prager, Q Xie, S Bao, JN Rich Cell stem cell 24 (1), 41-53, 2019 | 452 | 2019 |
| Targeting glioma stem cells through combined BMI1 and EZH2 inhibition X Jin, LJY Kim, Q Wu, LC Wallace, BC Prager, T Sanvoranart, RC Gimple, ... Nature medicine 23 (11), 1352-1361, 2017 | 333 | 2017 |
| Glioblastoma stem cells: driving resilience through chaos BC Prager, S Bhargava, V Mahadev, CG Hubert, JN Rich Trends in cancer 6 (3), 223-235, 2020 | 266 | 2020 |
| N6-methyladenine DNA modification in glioblastoma Q Xie, TP Wu, RC Gimple, Z Li, BC Prager, Q Wu, Y Yu, P Wang, Y Wang, ... Cell 175 (5), 1228-1243. e20, 2018 | 251 | 2018 |
| Zika virus has oncolytic activity against glioblastoma stem cells Z Zhu, MJ Gorman, LD McKenzie, JN Chai, CG Hubert, BC Prager, ... Journal of Experimental Medicine 214 (10), 2843-2857, 2017 | 241 | 2017 |
| The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells D Dixit, BC Prager, RC Gimple, HX Poh, Y Wang, Q Wu, Z Qiu, RL Kidwell, ... Cancer discovery 11 (2), 480-499, 2021 | 240 | 2021 |
| Reciprocal signaling between glioblastoma stem cells and differentiated tumor cells promotes malignant progression X Wang, BC Prager, Q Wu, LJY Kim, RC Gimple, Y Shi, K Yang, ... Cell stem cell 22 (4), 514-528. e5, 2018 | 218 | 2018 |
| Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101-105, 2018 | 194 | 2018 |
| Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions M Tang, Q Xie, RC Gimple, Z Zhong, T Tam, J Tian, RL Kidwell, Q Wu, ... Cell research 30 (10), 833-853, 2020 | 189 | 2020 |
| Targeting glioblastoma stem cells through disruption of the circadian clock Z Dong, G Zhang, M Qu, RC Gimple, Q Wu, Z Qiu, BC Prager, X Wang, ... Cancer discovery 9 (11), 1556-1573, 2019 | 183 | 2019 |
| Purine synthesis promotes maintenance of brain tumor initiating cells in glioma X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJY Kim, BC Prager, ... Nature neuroscience 20 (5), 661-673, 2017 | 170 | 2017 |
| Glioma stem cell–specific superenhancer promotes polyunsaturated fatty-acid synthesis to support EGFR signaling RC Gimple, RL Kidwell, LJY Kim, T Sun, AD Gromovsky, Q Wu, M Wolf, ... Cancer discovery 9 (9), 1248-1267, 2019 | 140 | 2019 |
| Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ... Cell stem cell 26 (2), 187-204. e10, 2020 | 138 | 2020 |
| Sphingosine 1-phosphate signaling at the blood–brain barrier B Prager, SF Spampinato, RM Ransohoff Trends in molecular medicine 21 (6), 354-363, 2015 | 125 | 2015 |
| Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells X Wang, K Yang, Q Wu, LJY Kim, AR Morton, RC Gimple, BC Prager, ... Science translational medicine 11 (504), eaau4972, 2019 | 122 | 2019 |
| MYC-regulated mevalonate metabolism maintains brain tumor–initiating cells X Wang, Z Huang, Q Wu, BC Prager, SC Mack, K Yang, LJY Kim, ... Cancer research 77 (18), 4947-4960, 2017 | 107 | 2017 |
| Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities A Choudhury, ST Magill, CD Eaton, BC Prager, WC Chen, MA Cady, ... Nature genetics 54 (5), 649-659, 2022 | 106 | 2022 |
| Nicotinamide metabolism regulates glioblastoma stem cell maintenance J Jung, LJY Kim, X Wang, Q Wu, T Sanvoranart, CG Hubert, BC Prager, ... JCI insight 2 (10), 2017 | 99 | 2017 |
| Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma SC Mack, I Singh, X Wang, R Hirsch, Q Wu, R Villagomez, JA Bernatchez, ... Journal of Experimental Medicine 216 (5), 1071-1090, 2019 | 98 | 2019 |
