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Sylvia P. Thomas
Sylvia P. Thomas
Verified email at uoguelph.ca
Title
Cited by
Cited by
Year
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency
MH Kang, LP van Lieshout, L Xu, JM Domm, A Vadivel, L Renesme, ...
Nature Communications 11 (1), 1-20, 2020
412020
Production of Adeno-Associated Virus Vectors in Cell Stacks for Preclinical Studies in Large Animal Models
AD Rghei, BAY Stevens, SP Thomas, JGE Yates, BM McLeod, K Karimi, ...
JoVE (Journal of Visualized Experiments), e62727, 2021
152021
Aav vectored immunoprophylaxis for filovirus infections
AD Rghei, LP van Lieshout, LA Santry, MM Guilleman, SP Thomas, ...
Tropical Medicine and Infectious Disease 5 (4), 169, 2020
132020
A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens
EN Gary, BM Warner, EM Parzych, BD Griffin, X Zhu, N Tailor, NJ Tursi, ...
iscience 24 (7), 102699, 2021
122021
Safety and tolerability of the adeno-associated virus vector, AAV6. 2FF, expressing a monoclonal antibody in murine and ovine animal models
AD Rghei, LP van Lieshout, BM McLeod, Y Pei, JA Lopes, N Zielinska, ...
Biomedicines 9 (9), 1186, 2021
92021
AAV-monoclonal antibody expression protects mice from Ebola virus without impeding the endogenous antibody response to heterologous challenge
LP van Lieshout, AD Rghei, W Cao, S He, G Soule, W Zhu, SP Thomas, ...
Molecular Therapy-Methods & Clinical Development 26, 505-518, 2022
82022
Generation and Characterization of a SARS-CoV-2-Susceptible Mouse Model Using Adeno-Associated Virus (AAV6. 2FF)-Mediated Respiratory Delivery of the Human ACE2 Gene
N Tailor, BM Warner, BD Griffin, K Tierney, E Moffat, K Frost, ...
Viruses 15 (1), 85, 2023
52023
AAV-vectored expression of the vascular normalizing agents 3TSR and Fc3TSR, and the anti-angiogenic bevacizumab extends survival in a murine model of end-stage epithelial …
AA Stegelmeier, LA Santry, MM Guilleman, K Matuszewska, JA Minott, ...
Biomedicines 10 (2), 362, 2022
32022
A promoterless AAV6. 2FF-based lung gene editing platform for the correction of surfactant protein B deficiency
SP Thomas, JM Domm, JP van Vloten, L Xu, A Vadivel, JGE Yates, Y Pei, ...
Molecular Therapy, 2023
22023
Extending the Longevity of AAV-mediated Lung Gene Therapy
S Thomas
https://hdl.handle.net/10214/27952, 2023
2023
Improving Efficiency of an AAV-CRISPR Platform for Lung Gene Editing
SP Thomas, JM Domm, JGE Yates, Y Pei, Y Mehrani, K Karimi, B Bridle, ...
MOLECULAR THERAPY 30 (4), 442-442, 2022
2022
Increasing AAV-CRISPR Gene Insertion Rates by Modulating DNA Repair Mechanisms
SP Thomas, W Zhang, B Thebaud, B Bridle, SK Wootton
MOLECULAR THERAPY 29 (4), 165-165, 2021
2021
A Novel Lung Tropic AAV Vector Restores Surfactant Homeostasis and Improves Survival in a Mouse Model of Inherited Surfactant B Deficiency
M Kang, LP Van Lieshout, L Xu, JM Domm, A Vadivel, L Renesme, ...
MOLECULAR THERAPY 28 (4), 69-70, 2020
2020
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