A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency MH Kang, LP van Lieshout, L Xu, JM Domm, A Vadivel, L Renesme, ... Nature Communications 11 (1), 1-20, 2020 | 41 | 2020 |
Production of Adeno-Associated Virus Vectors in Cell Stacks for Preclinical Studies in Large Animal Models AD Rghei, BAY Stevens, SP Thomas, JGE Yates, BM McLeod, K Karimi, ... JoVE (Journal of Visualized Experiments), e62727, 2021 | 15 | 2021 |
Aav vectored immunoprophylaxis for filovirus infections AD Rghei, LP van Lieshout, LA Santry, MM Guilleman, SP Thomas, ... Tropical Medicine and Infectious Disease 5 (4), 169, 2020 | 13 | 2020 |
A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens EN Gary, BM Warner, EM Parzych, BD Griffin, X Zhu, N Tailor, NJ Tursi, ... iscience 24 (7), 102699, 2021 | 12 | 2021 |
Safety and tolerability of the adeno-associated virus vector, AAV6. 2FF, expressing a monoclonal antibody in murine and ovine animal models AD Rghei, LP van Lieshout, BM McLeod, Y Pei, JA Lopes, N Zielinska, ... Biomedicines 9 (9), 1186, 2021 | 9 | 2021 |
AAV-monoclonal antibody expression protects mice from Ebola virus without impeding the endogenous antibody response to heterologous challenge LP van Lieshout, AD Rghei, W Cao, S He, G Soule, W Zhu, SP Thomas, ... Molecular Therapy-Methods & Clinical Development 26, 505-518, 2022 | 8 | 2022 |
Generation and Characterization of a SARS-CoV-2-Susceptible Mouse Model Using Adeno-Associated Virus (AAV6. 2FF)-Mediated Respiratory Delivery of the Human ACE2 Gene N Tailor, BM Warner, BD Griffin, K Tierney, E Moffat, K Frost, ... Viruses 15 (1), 85, 2023 | 5 | 2023 |
AAV-vectored expression of the vascular normalizing agents 3TSR and Fc3TSR, and the anti-angiogenic bevacizumab extends survival in a murine model of end-stage epithelial … AA Stegelmeier, LA Santry, MM Guilleman, K Matuszewska, JA Minott, ... Biomedicines 10 (2), 362, 2022 | 3 | 2022 |
A promoterless AAV6. 2FF-based lung gene editing platform for the correction of surfactant protein B deficiency SP Thomas, JM Domm, JP van Vloten, L Xu, A Vadivel, JGE Yates, Y Pei, ... Molecular Therapy, 2023 | 2 | 2023 |
Extending the Longevity of AAV-mediated Lung Gene Therapy S Thomas https://hdl.handle.net/10214/27952, 2023 | | 2023 |
Improving Efficiency of an AAV-CRISPR Platform for Lung Gene Editing SP Thomas, JM Domm, JGE Yates, Y Pei, Y Mehrani, K Karimi, B Bridle, ... MOLECULAR THERAPY 30 (4), 442-442, 2022 | | 2022 |
Increasing AAV-CRISPR Gene Insertion Rates by Modulating DNA Repair Mechanisms SP Thomas, W Zhang, B Thebaud, B Bridle, SK Wootton MOLECULAR THERAPY 29 (4), 165-165, 2021 | | 2021 |
A Novel Lung Tropic AAV Vector Restores Surfactant Homeostasis and Improves Survival in a Mouse Model of Inherited Surfactant B Deficiency M Kang, LP Van Lieshout, L Xu, JM Domm, A Vadivel, L Renesme, ... MOLECULAR THERAPY 28 (4), 69-70, 2020 | | 2020 |