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ARUNA KUMAR CHELLUBOYINA
ARUNA KUMAR CHELLUBOYINA
Grousbeck Gene Therapy Center, Mass Eye and Ear, Harvard Medical School
Verified email at MEEI.HARVARD.EDU - Homepage
Title
Cited by
Cited by
Year
Tumor targeting using polyamidoamine dendrimer–cisplatin nanoparticles functionalized with diglycolamic acid and herceptin
A Kesavan, P Ilaiyaraja, WS Beaula, VV Kumari, JS Lal, C Arunkumar, ...
European Journal of Pharmaceutics and Biopharmaceutics 96, 255-263, 2015
532015
Systems biology analyses show hyperactivation of transforming growth factor-β and JNK signaling pathways in esophageal cancer
AE Blum, S Venkitachalam, D Ravillah, AK Chelluboyina, ...
Gastroenterology 156 (6), 1761-1774, 2019
492019
Metabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence
A Kumar, N Welch, S Mishra, A Bellar, RN Silva, L Li, SS Singh, ...
JCI insight 6 (24), 2021
182021
Threonine 209 phosphorylation on RUNX3 by Pak1 is a molecular switch for its dualistic functions
A Kumar, M Singhal, C Chopra, S Srinivasan, RP Surabhi, R Kanumuri, ...
Oncogene 35 (37), 4857-4865, 2016
152016
Integrated multiomics analysis identifies molecular landscape perturbations during hyperammonemia in skeletal muscle and myotubes
N Welch, SS Singh, A Kumar, SR Dhruba, S Mishra, J Sekar, A Bellar, ...
Journal of Biological Chemistry 297 (3), 2021
102021
Dysregulated cellular redox status during hyperammonemia causes mitochondrial dysfunction and senescence by inhibiting sirtuin‐mediated deacetylation
S Mishra, N Welch, M Karthikeyan, A Bellar, R Musich, SS Singh, D Zhang, ...
Aging Cell 22 (7), e13852, 2023
62023
Small peptide inhibitor from the sequence of RUNX3 disrupts PAK1–RUNX3 interaction and abrogates its phosphorylation-dependent oncogenic function
R Kanumuri, AK Chelluboyina, J Biswal, R Vignesh, J Pandian, A Venu, ...
Oncogene 40 (34), 5327-5341, 2021
52021
UnPAKing RUNX3 functions–Both sides of the coin
A Kumar, S Sundaram, SK Rayala, G Venkatraman
Small GTPases 10 (4), 264-270, 2019
42019
Shared and unique phosphoproteomics responses in skeletal muscle from exercise models and in hyperammonemic myotubes
N Welch, SS Singh, R Musich, MS Mansuri, A Bellar, S Mishra, ...
Iscience 25 (11), 2022
12022
Hyperammonemia-induced mitochondrial dysfunction causes skeletal muscle senescence and sarcopenia which are reversed by ammonia lowering interventions
A Kumar, N Welch, S Mishra, A Bellar, RS Nasciemento, SS Singh, ...
Hepatology 74, 36A-36A, 2021
12021
Intermittent hypoxia causes skeletal muscle protein OGlc-Nacylation: A potential mediator of sarcopenia in COPD
A Attaway, N Welch, M Engelen, R Tabbalat, J Ragunathan, SS Singh, ...
GLYCOBIOLOGY 31 (12), 1712-1713, 2021
2021
THE GUT MICROBE-DERIVED XENOMETABOLITE TRIMETHYLAMINE PROMOTES SARCOPENIA AND MITOCHONDRIAL DYSFUNCTION IN ALCOHOL RELATED LIVER DISEASE.
A Bellar, N Welch, A Kumar, J Sekar, SS Singh, S Mishra, A Kadam, ...
HEPATOLOGY 74, 259A-259A, 2021
2021
INTEGRATED UNTARGETED METABOLOMICS REVEAL DYSREGULATED AMINOACYL-tRNA BIOSYNTHESIS AND GLYOXYLATE/DICARBOXYLATE METABOLISM AS NOVEL PERTURBATIONS IN HYPERAMMONEMIA MEDIATED …
N Welch, A Kerr, M Goudarzi, SS Singh, J Sekar, A Kumar, S Mishra, ...
HEPATOLOGY 74, 285A-285A, 2021
2021
UNBIASED SKELETAL MUSCLE METABOLOMICS IN ETHANOL-TREATED MYOTUBES PREDICTS NOVEL TREATMENT TARGETS IN SARCOPENIA OF ALCOHOL ASSOCIATED LIVER DISEASE.
N Welch, A Kerr, M Goudarzi, SS Singh, J Sekar, A Kumar, S Mishra, ...
HEPATOLOGY 74, 264A-264A, 2021
2021
HYPERAMMONEMIA INDUCED SKELETAL MUSCLE MITOCHONDRIAL DYSFUNCTION IS MEDIATED BY AMPK AND CONTRIBUTES TO SARCOPENIA IN CIRRHOSIS IN A SEX INDEPENDENT MANNER
A Bellar, A Kumar, N Welch, M Sharkoff, M Gangadhariah, AF Vural, ...
HEPATOLOGY 74, 284A-285A, 2021
2021
COUPLED AMMONIA TRANSPORT AND SIGNALING VIA RHBG IN SKELETAL MUSCLE DURING HYPERAMMONEMIA
SS Singh, J Sekar, N Welch, DS Khuraijam, A Kumar, A Bellar, S Mishra, ...
HEPATOLOGY 74, 281A-282A, 2021
2021
The EphB2-MYC Axis is a Major Determinant of Barrett’s Pathobiology and a Therapeutic Vulnerability in Esophageal Cancer
S Venkitachalam, D Babu, D Ravillah, RM Katabathula, P Joseph, ...
bioRxiv, 2021.05. 13.444044, 2021
2021
CLUSTERED MOLECULAR RESPONSES TO HYPERAMMONEMIA MEDIATE SARCOPENIA IN CIRRHOSIS WITH ACCELERATED SKELETAL MUSCLE SENESCENCE
N Welch, SS Singh, A Kumar, SR Dhruba, S Mishra, J Sekar, A Bellar, ...
2021
Su1062–Molecular Dependencies in Esophageal Adenocarcinoma: A Systems Biology Approach
S Venkitachalam, A Blum, D Ravillah, AK Chelluboyina, ...
Gastroenterology 156 (6), S-498-S-499, 2019
2019
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