SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell Stem Cell 29 (2), 217-231. e8, 2022 | 175 | 2022 |
A crystallographic snapshot of SARS-CoV-2 main protease maturation process GD Noske, AM Nakamura, VO Gawriljuk, RS Fernandes, GMA Lima, ... Journal of Molecular Biology 433 (18), 167118, 2021 | 53 | 2021 |
Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease GD Noske, E de Souza Silva, MO de Godoy, I Dolci, RS Fernandes, ... Journal of Biological Chemistry 299 (3), 2023 | 40 | 2023 |
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ... BioRxiv, 2020.10. 29.339317, 2020 | 36 | 2020 |
Reporter replicons for antiviral drug discovery against positive single-stranded RNA viruses RS Fernandes, MCLC Freire, RV Bueno, AS Godoy, LHVG Gil, G Oliva Viruses 12 (6), 598, 2020 | 31 | 2020 |
Non-toxic dimeric peptides derived from the bothropstoxin-I are potent SARS-CoV-2 and papain-like protease inhibitors MCLC Freire, GD Noske, NV Bitencourt, PRS Sanches, NA Santos-Filho, ... Molecules 26 (16), 4896, 2021 | 28 | 2021 |
Antibacterial Activity of the Non-Cytotoxic Peptide (p-BthTX-I)2 and Its Serum Degradation Product against Multidrug-Resistant Bacteria NA Santos-Filho, RS Fernandes, BF Sgardioli, MAS Ramos, JP Piccoli, ... Molecules 22 (11), 1898, 2017 | 27 | 2017 |
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ... Science 382 (6671), eabo7201, 2023 | 26 | 2023 |
Discovery of an imidazonaphthyridine and a riminophenazine as potent anti-Zika virus agents through a replicon-based high-throughput screening RS Fernandes, AS de Godoy, IA Santos, GD Noske, KIZ de Oliveira, ... Virus Research 299, 198388, 2021 | 21 | 2021 |
Structural characterization and polymorphism analysis of the NS2B-NS3 protease from the 2017 Brazilian circulating strain of Yellow Fever virus GD Noske, VO Gawriljuk, RS Fernandes, ND Furtado, MC Bonaldo, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (4), 129521, 2020 | 17 | 2020 |
Pyronaridine protects against SARS-CoV-2 infection in mouse AC Puhl, GF Gomes, S Damasceno, AS Godoy, GD Noske, AM Nakamura, ... ACS Infectious Diseases 8 (6), 1147-1160, 2022 | 16 | 2022 |
Stage and tissue expression patterns of Schistosoma mansoni venom allergen-like proteins SmVAL 4, 13, 16 and 24 RS Fernandes, TC Barbosa, MMF Barbosa, PA Miyasato, E Nakano, ... Parasites & vectors 10, 1-13, 2017 | 13 | 2017 |
Study of viral photoinactivation by UV-C light and photosensitizer using a pseudotyped model M Sadraeian, FFP Junior, M Miranda, J Galinskas, RS Fernandes, ... Pharmaceutics 14 (3), 683, 2022 | 11 | 2022 |
Schistosoma mansoni venom allergen-like protein 18 (SmVAL18) is a plasminogen-binding protein secreted during the early stages of mammalian-host infection RS Fernandes, LGV Fernandes, AS de Godoy, PA Miyasato, E Nakano, ... Molecular and biochemical parasitology 221, 23-31, 2018 | 11 | 2018 |
An in-solution snapshot of SARS-COV-2 main protease maturation process and inhibition GD Noske, Y Song, RS Fernandes, R Chalk, H Elmassoudi, L Koekemoer, ... Nature Communications 14 (1), 1545, 2023 | 8 | 2023 |
Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate MCLC Freire, LGM Basso, LFS Mendes, NCMR Mesquita, M Mottin, ... Scientific reports 12 (1), 10601, 2022 | 8 | 2022 |
High-throughput antiviral assays to screen for inhibitors of Zika virus replication RS Fernandes, GD Noske, VO Gawriljuk, KIZ de Oliveira, AS Godoy, ... JoVE (Journal of Visualized Experiments), e62422, 2021 | 8 | 2021 |
Systems biology analysis of the radiation-attenuated schistosome vaccine reveals a role for growth factors in protection and hemostasis inhibition in parasite survival LP Farias, J Vitoriano-Souza, LE Cardozo, LDR Gama, Y Singh, ... Frontiers in Immunology 12, 624191, 2021 | 8 | 2021 |
Structural and mechanistic insight from antiviral and antiparasitic enzyme drug targets for tropical infectious diseases AS de Godoy, RS Fernandes, ACC Aguiar, RV Bueno, NCMR Mesquita, ... Current Opinion in Structural Biology 59, 65-72, 2019 | 7 | 2019 |
Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease AS Godoy, AM Nakamura, A Douangamath, Y Song, GD Noske, ... Nucleic Acids Research 51 (10), 5255-5270, 2023 | 6 | 2023 |