SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 195 | 2022 |
Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease GD Noske, E de Souza Silva, MO de Godoy, I Dolci, RS Fernandes, ... Journal of Biological Chemistry 299 (3), 2023 | 63 | 2023 |
A crystallographic snapshot of SARS-CoV-2 main protease maturation process GD Noske, AM Nakamura, VO Gawriljuk, RS Fernandes, GMA Lima, ... Journal of Molecular Biology 433 (18), 167118, 2021 | 59 | 2021 |
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ... Science 382 (6671), eabo7201, 2023 | 53 | 2023 |
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ... BioRxiv, 2020.10. 29.339317, 2020 | 39 | 2020 |
Reporter replicons for antiviral drug discovery against positive single-stranded RNA viruses RS Fernandes, MCLC Freire, RV Bueno, AS Godoy, LHVG Gil, G Oliva Viruses 12 (6), 598, 2020 | 34 | 2020 |
Antibacterial Activity of the Non-Cytotoxic Peptide (p-BthTX-I)2 and Its Serum Degradation Product against Multidrug-Resistant Bacteria NA Santos-Filho, RS Fernandes, BF Sgardioli, MAS Ramos, JP Piccoli, ... Molecules 22 (11), 1898, 2017 | 31 | 2017 |
Non-toxic dimeric peptides derived from the bothropstoxin-I are potent SARS-CoV-2 and papain-like protease inhibitors MCLC Freire, GD Noske, NV Bitencourt, PRS Sanches, NA Santos-Filho, ... Molecules 26 (16), 4896, 2021 | 28 | 2021 |
Discovery of an imidazonaphthyridine and a riminophenazine as potent anti-Zika virus agents through a replicon-based high-throughput screening RS Fernandes, AS de Godoy, IA Santos, GD Noske, KIZ de Oliveira, ... Virus Research 299, 198388, 2021 | 23 | 2021 |
Structural characterization and polymorphism analysis of the NS2B-NS3 protease from the 2017 Brazilian circulating strain of Yellow Fever virus GD Noske, VO Gawriljuk, RS Fernandes, ND Furtado, MC Bonaldo, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (4), 129521, 2020 | 21 | 2020 |
Pyronaridine protects against SARS-CoV-2 infection in mouse AC Puhl, GF Gomes, S Damasceno, AS Godoy, GD Noske, AM Nakamura, ... ACS Infectious Diseases 8 (6), 1147-1160, 2022 | 19 | 2022 |
Stage and tissue expression patterns of Schistosoma mansoni venom allergen-like proteins SmVAL 4, 13, 16 and 24 RS Fernandes, TC Barbosa, MMF Barbosa, PA Miyasato, E Nakano, ... Parasites & vectors 10, 1-13, 2017 | 13 | 2017 |
Study of viral photoinactivation by UV-C light and photosensitizer using a pseudotyped model M Sadraeian, FFP Junior, M Miranda, J Galinskas, RS Fernandes, ... Pharmaceutics 14 (3), 683, 2022 | 12 | 2022 |
Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease AS Godoy, AM Nakamura, A Douangamath, Y Song, GD Noske, ... Nucleic Acids Research 51 (10), 5255-5270, 2023 | 11 | 2023 |
An in-solution snapshot of SARS-COV-2 main protease maturation process and inhibition GD Noske, Y Song, RS Fernandes, R Chalk, H Elmassoudi, L Koekemoer, ... Nature Communications 14 (1), 1545, 2023 | 11 | 2023 |
Schistosoma mansoni venom allergen-like protein 18 (SmVAL18) is a plasminogen-binding protein secreted during the early stages of mammalian-host infection RS Fernandes, LGV Fernandes, AS de Godoy, PA Miyasato, E Nakano, ... Molecular and biochemical parasitology 221, 23-31, 2018 | 11 | 2018 |
Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate MCLC Freire, LGM Basso, LFS Mendes, NCMR Mesquita, M Mottin, ... Scientific reports 12 (1), 10601, 2022 | 10 | 2022 |
Discovery of PLpro and Mpro Inhibitors for SARS-CoV-2 AC Puhl, AS Godoy, GD Noske, AM Nakamura, VO Gawriljuk, ... ACS omega 8 (25), 22603-22612, 2023 | 8 | 2023 |
High-throughput antiviral assays to screen for inhibitors of Zika virus replication RS Fernandes, GD Noske, VO Gawriljuk, KIZ de Oliveira, AS Godoy, ... JoVE (Journal of Visualized Experiments), e62422, 2021 | 8 | 2021 |
Systems biology analysis of the radiation-attenuated schistosome vaccine reveals a role for growth factors in protection and hemostasis inhibition in parasite survival LP Farias, J Vitoriano-Souza, LE Cardozo, LDR Gama, Y Singh, ... Frontiers in Immunology 12, 624191, 2021 | 8 | 2021 |