The Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) trial programme; rationale, design and baseline characteristics including a meta-analysis of the effects … SR Mehta, S Yusuf European heart journal 21 (24), 2033-2041, 2000 | 480 | 2000 |
Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function CW Wright, CS Duckett The Journal of clinical investigation 115 (10), 2673-2678, 2005 | 161 | 2005 |
CD30 activates both the canonical and alternative NF-κB pathways in anaplastic large cell lymphoma cells CW Wright, JM Rumble, CS Duckett Journal of Biological Chemistry 282 (14), 10252-10262, 2007 | 96 | 2007 |
The Aryl Hydrocarbon Nuclear Translocator Alters CD30-Mediated NF-κB–Dependent Transcription CW Wright, CS Duckett Science 323 (5911), 251-255, 2009 | 63 | 2009 |
Cytoprotective effects of IAPs revealed by a small molecule antagonist S Galbán, C Hwang, JM Rumble, KA Oetjen, CW Wright, A Boudreault, ... Biochemical Journal 417 (3), 765-771, 2009 | 59 | 2009 |
EZH2 regulates the transcription of estrogen-responsive genes through association with REA, an estrogen receptor corepressor C Hwang, VN Giri, JC Wilkinson, CW Wright, AS Wilkinson, KA Cooney, ... Breast cancer research and treatment 107, 235-242, 2008 | 57 | 2008 |
Sequence requirements for Hid binding and apoptosis regulation in the baculovirus inhibitor of apoptosis Op-IAP: Hid binds Op-IAP in a manner similar to Smac binding of XIAP CW Wright, RJ Clem Journal of Biological Chemistry 277 (4), 2454-2462, 2002 | 47 | 2002 |
The baculovirus anti-apoptotic protein Op-IAP does not inhibit Drosophila caspases or apoptosis in Drosophila S2 cells and instead sensitizes S2 cells to virus-induced apoptosis CW Wright, JC Means, T Penabaz, RJ Clem Virology 335 (1), 61-71, 2005 | 41 | 2005 |
Nuclear factor-κB-inducing kinase (NIK) contains an amino-terminal inhibitor of apoptosis (IAP)-binding motif (IBM) that potentiates NIK degradation by cellular IAP1 (c-IAP1) S Lee, M Challa-Malladi, SB Bratton, CW Wright Journal of Biological Chemistry 289 (44), 30680-30689, 2014 | 35 | 2014 |
Mitochondrial uncoupling links lipid catabolism to Akt inhibition and resistance to tumorigenesis SM Nowinski, A Solmonson, JE Rundhaug, O Rho, J Cho, CU Lago, ... Nature communications 6 (1), 8137, 2015 | 34 | 2015 |
Aryl hydrocarbon receptor nuclear translocator (ARNT) isoforms control lymphoid cancer cell proliferation through differentially regulating tumor suppressor p53 activity KA Gardella, I Muro, G Fang, K Sarkar, O Mendez, CW Wright Oncotarget 7 (10), 10710, 2016 | 31 | 2016 |
Apoptotic sensitivity of murine IAP-deficient cells JM Rumble, MJM Bertrand, RA Csomos, CW Wright, L Albert, TW Mak, ... Biochemical Journal 415 (1), 21-25, 2008 | 28 | 2008 |
Two distinct signalling cascades target the NF-κB regulatory factor c-IAP1 for degradation RA Csomos, CW Wright, S Galbán, KA Oetjen, CS Duckett Biochemical Journal 420 (1), 83-91, 2009 | 22 | 2009 |
BH3-only protein BIM mediates heat shock-induced apoptosis IM Mahajan, MD Chen, I Muro, JD Robertson, CW Wright, SB Bratton PLoS One 9 (1), e84388, 2014 | 21 | 2014 |
The TRAF3 adaptor protein drives proliferation of anaplastic large cell lymphoma cells by regulating multiple signaling pathways I Muro, G Fang, K Gardella, I Mahajan, C Wright Cell Cycle 13 (12), 1918-1927, 2014 | 18 | 2014 |
Alternative splicing of the aryl hydrocarbon receptor nuclear translocator (ARNT) is regulated by RBFOX2 in lymphoid malignancies AM Cooper, CA Nutter, MN Kuyumcu-Martinez, CW Wright Molecular and cellular biology 42 (5), e00503-21, 2022 | 8 | 2022 |
AhR promotes phosphorylation of ARNT isoform 1 in human T cell malignancies as a switch for optimal AhR activity LA Bourner, I Muro, AM Cooper, BK Choudhury, AO Bailey, WK Russell, ... Proceedings of the National Academy of Sciences 119 (12), e2114336119, 2022 | 7 | 2022 |
New insights into the function of IAP proteins: modulation of the MYC/MAX/MAD network CW Wright, CS Duckett Developmental cell 14 (1), 3-4, 2008 | 6 | 2008 |
Efficacy of Lophira alata leaf extract and its combination with artesunate in mice prior exposed to Plasmodium berghei MO Falade, F Komoni, RI Nwuba Drug Research 68 (04), 232-237, 2018 | 4 | 2018 |
Lymphoid malignancies ARNT unstoppable KA Gardella, R Tiwary, CW Wright Aging (Albany NY) 8 (7), 1292, 2016 | 2 | 2016 |