Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study SM Domchek, S Postel-Vinay, SA Im, YH Park, JP Delord, A Italiano, ... The Lancet Oncology 21 (9), 1155-1164, 2020 | 330 | 2020 |
TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity PD Uchil, A Hinz, S Siegel, A Coenen-Stass, T Pertel, J Luban, W Mothes Journal of virology 87 (1), 257-272, 2013 | 234 | 2013 |
Assessment of RT-qPCR normalization strategies for accurate quantification of extracellular microRNAs in murine serum TC Roberts, AML Coenen-Stass, MJA Wood PloS one 9 (2), e89237, 2014 | 147 | 2014 |
Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense oligonucleotides K Ezzat, Y Aoki, T Koo, G McClorey, L Benner, A Coenen-Stass, ... Nano letters 15 (7), 4364-4373, 2015 | 103 | 2015 |
Evaluation of methodologies for microRNA biomarker detection by next generation sequencing AML Coenen-Stass, I Magen, T Brooks, IZ Ben-Dov, L Greensmith, ... RNA biology 15 (8), 1133-1145, 2018 | 101 | 2018 |
Longitudinal immune characterization of syngeneic tumor models to enable model selection for immune oncology drug discovery MA Taylor, AM Hughes, J Walton, AML Coenen-Stass, L Magiera, ... Journal for ImmunoTherapy of Cancer 7, 1-16, 2019 | 78 | 2019 |
PI3Kα/δ inhibition promotes anti-tumor immunity through direct enhancement of effector CD8+ T-cell activity LS Carnevalli, C Sinclair, MA Taylor, PM Gutierrez, S Langdon, ... Journal for immunotherapy of cancer 6 (1), 158, 2018 | 76 | 2018 |
Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosis I Magen, NS Yacovzada, E Yanowski, A Coenen-Stass, J Grosskreutz, ... Nature neuroscience 24 (11), 1534-1541, 2021 | 71 | 2021 |
Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics AML Coenen-Stass, G McClorey, R Manzano, CA Betts, A Blain, AF Saleh, ... Scientific reports 5 (1), 17014, 2015 | 67 | 2015 |
Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies J Rouillon, J Poupiot, A Zocevic, F Amor, T Léger, C Garcia, JM Camadro, ... Human molecular genetics 24 (17), 4916-4932, 2015 | 67 | 2015 |
Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics AML Coenen-Stass, MJ Pauwels, B Hanson, C Martin Perez, ... RNA biology 16 (5), 696-706, 2019 | 65 | 2019 |
Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice CA Betts, AF Saleh, CA Carr, SM Hammond, AML Coenen-Stass, ... Scientific reports 5 (1), 8986, 2015 | 63 | 2015 |
Biomarker potential of extracellular miRNAs in Duchenne muscular dystrophy AML Coenen-Stass, MJA Wood, TC Roberts Trends in molecular medicine 23 (11), 989-1001, 2017 | 62 | 2017 |
Selective release of muscle-specific, extracellular microRNAs during myogenic differentiation AML Coenen-Stass, CA Betts, YF Lee, I Mäger, MP Turunen, ... Human Molecular Genetics 25 (18), 3960-3974, 2016 | 58 | 2016 |
Detection and quantification of extracellular microRNAs in murine biofluids TC Roberts, AML Coenen-Stass, CA Betts, MJA Wood Biological procedures online 16, 1-15, 2014 | 54 | 2014 |
Comprehensive RNA-sequencing analysis in serum and muscle reveals novel small RNA signatures with biomarker potential for DMD AML Coenen-Stass, H Sork, S Gatto, C Godfrey, A Bhomra, K Krjutškov, ... Molecular Therapy-Nucleic Acids 13, 1-15, 2018 | 45 | 2018 |
Mutation-independent proteomic signatures of pathological progression in murine models of Duchenne muscular dystrophy TLE van Westering, HJ Johansson, B Hanson, AML Coenen-Stass, ... Molecular & Cellular Proteomics 19 (12), 2047-2068, 2020 | 25 | 2020 |
Uniform sarcolemmal dystrophin expression is required to prevent extracellular microRNA release and improve dystrophic pathology TLE van Westering, Y Lomonosova, AML Coenen‐Stass, CA Betts, ... Journal of Cachexia, Sarcopenia and Muscle 11 (2), 578-593, 2020 | 25 | 2020 |
Extracellular microRNAs in membrane vesicles and non-vesicular carriers AML Coenen-Stass, I Mäger, MJA Wood Circulating microRNAs in Disease Diagnostics and their Potential Biological …, 2015 | 15 | 2015 |
Macrophage activation status rather than repolarization is associated with enhanced checkpoint activity in combination with PI3Kγ Inhibition LS Carnevalli, MA Taylor, M King, AML Coenen-Stass, AM Hughes, S Bell, ... Molecular Cancer Therapeutics 20 (6), 1080-1091, 2021 | 8 | 2021 |