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Karthik Mosur Krishnan
Karthik Mosur Krishnan
Food and Drug Administration
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HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus
K Krishnan, X Feng, DL Richie, V Aimanianda, L Hartl, N Grahl, ...
PLoS pathogens 7 (10), e1002330, 2011
1192011
Divergent Protein Kinase A isoforms co‐ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus
KK Fuller, DL Richie, X Feng, K Krishnan, TJ Stephens, ...
Molecular microbiology 79 (4), 1045-1062, 2011
702011
The fungal UPR: A regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus
K Krishnan, DS Askew
Virulence 5 (2), 334-340, 2014
492014
The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation …
DL Richie, X Feng, L Hartl, V Aimanianda, K Krishnan, ...
Virulence 2 (1), 12-21, 2011
482011
The proteasome as a target to combat malaria: hits and misses
KM Krishnan, KC Williamson
Translational Research 198, 40-47, 2018
452018
Endoplasmic reticulum stress and fungal pathogenesis
K Krishnan, DS Askew
Fungal biology reviews 28 (2-3), 29-35, 2014
422014
Proximity of the Start Codon to a Leaderless mRNA's 5′ Terminus Is a Strong Positive Determinant of Ribosome Binding and Expression in Escherichia coli
KM Krishnan, WJ Van Etten III, GR Janssen
Journal of bacteriology 192 (24), 6482-6485, 2010
372010
Polysome profiling reveals broad translatome remodeling during endoplasmic reticulum (ER) stress in the pathogenic fungus Aspergillus fumigatus
K Krishnan, Z Ren, L Losada, WC Nierman, LJ Lu, DS Askew
BMC genomics 15, 1-14, 2014
302014
Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen …
K Krishnan, X Feng, MV Powers-Fletcher, G Bick, DL Richie, LA Woollett, ...
Eukaryotic cell 12 (4), 512-519, 2013
302013
Deletion of the sec4 homolog srgA from Aspergillus fumigatus is associated with an impaired stress response, attenuated virulence and phenotypic heterogeneity
MV Powers-Fletcher, X Feng, K Krishnan, DS Askew
PloS one 8 (6), e66741, 2013
232013
Torin 2 Derivative, NCATS-SM3710, Has Potent Multistage Antimalarial Activity through Inhibition of P. falciparum Phosphatidylinositol 4-Kinase (Pf PI4KIIIβ)
K Krishnan, P Ziniel, H Li, X Huang, D Hupalo, N Gombakomba, ...
ACS Pharmacology & Translational Science 3 (5), 948-964, 2020
222020
Antifungal activity of the lipophilic antioxidant ferrostatin‐1
MC Horwath, TR Bell‐Horwath, V Lescano, K Krishnan, EJ Merino, ...
Chembiochem 18 (20), 2069-2078, 2017
222017
Functional Coupling between the Unfolded Protein Response and Endoplasmic Reticulum/Golgi Ca2+-ATPases Promotes Stress Tolerance, Cell Wall …
M Weichert, J Guirao-Abad, V Aimanianda, K Krishnan, C Grisham, ...
MBio 11 (3), 10.1128/mbio. 01060-20, 2020
172020
Impact of the lectin chaperone calnexin on the stress response, virulence and proteolytic secretome of the fungal pathogen Aspergillus fumigatus
MV Powers-Fletcher, K Jambunathan, JL Brewer, K Krishnan, X Feng, ...
PLoS One 6 (12), e28865, 2011
172011
The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the …
DL Richie, X Feng, L Hartl, V Aimanianda, K Krishnan, ...
Epub 2011/01/11. https://doi. org/10.4161/viru. 2.1. 13345 PMID: 21217201, 2011
152011
Secretion stress and antifungal resistance: An Achilles’ heel of Aspergillus fumigatus?
DL Richie, X Feng, K Krishnan, DS Askew
Medical Mycology 49 (sup1), S101-S106, 2011
132011
Endoplasmic reticulum stress and fungal pathogenesis. Fungal Biol Rev 28: 29–35
K Krishnan, DS Askew
122014
The toxicity of a novel antifungal compound is modulated by endoplasmic reticulum-associated protein degradation components
S Raj, K Krishnan, DS Askew, O Helynck, P Suzanne, A Lesnard, S Rault, ...
Antimicrobial Agents and Chemotherapy 60 (3), 1438-1449, 2016
92016
The fungal UPR: a regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus. Virulence. 2014; 5 (2): 334–40
K Krishnan, DS Askew
Epub 2013/11/06. doi: 10.4161/viru. 26571 26571 [pii]. PMID: 24189125, 0
2
The virulence of the opportunistic fungal pathogen
DL Richie, XZ Feng, L Hartl, V Aimanianda, K Krishnan, ...
Aspergillus fumigatus, 12-21, 0
2
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Articles 1–20