HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus K Krishnan, X Feng, DL Richie, V Aimanianda, L Hartl, N Grahl, ... PLoS pathogens 7 (10), e1002330, 2011 | 119 | 2011 |
Divergent Protein Kinase A isoforms co‐ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus KK Fuller, DL Richie, X Feng, K Krishnan, TJ Stephens, ... Molecular microbiology 79 (4), 1045-1062, 2011 | 70 | 2011 |
The fungal UPR: A regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus K Krishnan, DS Askew Virulence 5 (2), 334-340, 2014 | 49 | 2014 |
The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation … DL Richie, X Feng, L Hartl, V Aimanianda, K Krishnan, ... Virulence 2 (1), 12-21, 2011 | 48 | 2011 |
The proteasome as a target to combat malaria: hits and misses KM Krishnan, KC Williamson Translational Research 198, 40-47, 2018 | 45 | 2018 |
Endoplasmic reticulum stress and fungal pathogenesis K Krishnan, DS Askew Fungal biology reviews 28 (2-3), 29-35, 2014 | 42 | 2014 |
Proximity of the Start Codon to a Leaderless mRNA's 5′ Terminus Is a Strong Positive Determinant of Ribosome Binding and Expression in Escherichia coli KM Krishnan, WJ Van Etten III, GR Janssen Journal of bacteriology 192 (24), 6482-6485, 2010 | 37 | 2010 |
Polysome profiling reveals broad translatome remodeling during endoplasmic reticulum (ER) stress in the pathogenic fungus Aspergillus fumigatus K Krishnan, Z Ren, L Losada, WC Nierman, LJ Lu, DS Askew BMC genomics 15, 1-14, 2014 | 30 | 2014 |
Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen … K Krishnan, X Feng, MV Powers-Fletcher, G Bick, DL Richie, LA Woollett, ... Eukaryotic cell 12 (4), 512-519, 2013 | 30 | 2013 |
Deletion of the sec4 homolog srgA from Aspergillus fumigatus is associated with an impaired stress response, attenuated virulence and phenotypic heterogeneity MV Powers-Fletcher, X Feng, K Krishnan, DS Askew PloS one 8 (6), e66741, 2013 | 23 | 2013 |
Torin 2 Derivative, NCATS-SM3710, Has Potent Multistage Antimalarial Activity through Inhibition of P. falciparum Phosphatidylinositol 4-Kinase (Pf PI4KIIIβ) K Krishnan, P Ziniel, H Li, X Huang, D Hupalo, N Gombakomba, ... ACS Pharmacology & Translational Science 3 (5), 948-964, 2020 | 22 | 2020 |
Antifungal activity of the lipophilic antioxidant ferrostatin‐1 MC Horwath, TR Bell‐Horwath, V Lescano, K Krishnan, EJ Merino, ... Chembiochem 18 (20), 2069-2078, 2017 | 22 | 2017 |
Functional Coupling between the Unfolded Protein Response and Endoplasmic Reticulum/Golgi Ca2+-ATPases Promotes Stress Tolerance, Cell Wall … M Weichert, J Guirao-Abad, V Aimanianda, K Krishnan, C Grisham, ... MBio 11 (3), 10.1128/mbio. 01060-20, 2020 | 17 | 2020 |
Impact of the lectin chaperone calnexin on the stress response, virulence and proteolytic secretome of the fungal pathogen Aspergillus fumigatus MV Powers-Fletcher, K Jambunathan, JL Brewer, K Krishnan, X Feng, ... PLoS One 6 (12), e28865, 2011 | 17 | 2011 |
The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the … DL Richie, X Feng, L Hartl, V Aimanianda, K Krishnan, ... Epub 2011/01/11. https://doi. org/10.4161/viru. 2.1. 13345 PMID: 21217201, 2011 | 15 | 2011 |
Secretion stress and antifungal resistance: An Achilles’ heel of Aspergillus fumigatus? DL Richie, X Feng, K Krishnan, DS Askew Medical Mycology 49 (sup1), S101-S106, 2011 | 13 | 2011 |
Endoplasmic reticulum stress and fungal pathogenesis. Fungal Biol Rev 28: 29–35 K Krishnan, DS Askew | 12 | 2014 |
The toxicity of a novel antifungal compound is modulated by endoplasmic reticulum-associated protein degradation components S Raj, K Krishnan, DS Askew, O Helynck, P Suzanne, A Lesnard, S Rault, ... Antimicrobial Agents and Chemotherapy 60 (3), 1438-1449, 2016 | 9 | 2016 |
The fungal UPR: a regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus. Virulence. 2014; 5 (2): 334–40 K Krishnan, DS Askew Epub 2013/11/06. doi: 10.4161/viru. 26571 26571 [pii]. PMID: 24189125, 0 | 2 | |
The virulence of the opportunistic fungal pathogen DL Richie, XZ Feng, L Hartl, V Aimanianda, K Krishnan, ... Aspergillus fumigatus, 12-21, 0 | 2 | |