A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes SR Wilkinson, MC Taylor, D Horn, JM Kelly, I Cheeseman Proceedings of the National Academy of Sciences 105 (13), 5022-5027, 2008 | 520 | 2008 |
Mechanism of genetic exchange in American trypanosomes MW Gaunt, M Yeo, IA Frame, JR Stothard, HJ Carrasco, MC Taylor, ... Nature 421 (6926), 936-939, 2003 | 464 | 2003 |
Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue‐specific parasite dynamics and heart disease in the absence of locally persistent … MD Lewis, A Fortes Francisco, MC Taylor, H Burrell‐Saward, ... Cellular microbiology 16 (9), 1285-1300, 2014 | 237 | 2014 |
Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase … L Piacenza, F Irigoín, MN Alvarez, G Peluffo, MC Taylor, JM Kelly, ... Biochemical Journal 403 (2), 323-334, 2007 | 180 | 2007 |
The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin SR Wilkinson, DJ Meyer, MC Taylor, EV Bromley, MA Miles, JM Kelly Journal of Biological Chemistry 277 (19), 17062-17071, 2002 | 171 | 2002 |
Rad51 paralogs remodel pre-synaptic Rad51 filaments to stimulate homologous recombination MRG Taylor, M Špírek, KR Chaurasiya, JD Ward, R Carzaniga, X Yu, ... Cell 162 (2), 271-286, 2015 | 164 | 2015 |
Benznidazole-Resistance in Trypanosoma cruzi Is a Readily Acquired Trait That Can Arise Independently in a Single Population AM Mejia, BS Hall, MC Taylor, A Gómez-Palacio, SR Wilkinson, ... The Journal of infectious diseases 206 (2), 220-228, 2012 | 156 | 2012 |
β-d-Glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres F Van Leeuwen, MC Taylor, A Mondragon, H Moreau, W Gibson, R Kieft, ... Proceedings of the National Academy of Sciences 95 (5), 2366-2371, 1998 | 156 | 1998 |
Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging AF Francisco, MD Lewis, S Jayawardhana, MC Taylor, E Chatelain, ... Antimicrobial agents and chemotherapy 59 (8), 4653-4661, 2015 | 147 | 2015 |
The initial response of a eukaryotic replisome to DNA damage MRG Taylor, JTP Yeeles Molecular cell 70 (6), 1067-1080. e12, 2018 | 129 | 2018 |
Benznidazole-resistance in Trypanosoma cruzi: evidence that distinct mechanisms can act in concert MCO Campos, LL Leon, MC Taylor, JM Kelly Molecular and biochemical parasitology 193 (1), 17-19, 2014 | 120 | 2014 |
Functional characterisation of the iron superoxide dismutase gene repertoire in Trypanosoma brucei SR Wilkinson, SR Prathalingam, MC Taylor, A Ahmed, D Horn, JM Kelly Free Radical Biology and Medicine 40 (2), 198-209, 2006 | 119 | 2006 |
VSG gene expression site control in insect form Trypanosoma brucei. G Rudenko, PA Blundell, MC Taylor, R Kieft, P Borst The EMBO journal 13 (22), 5470-5482, 1994 | 117 | 1994 |
Distinct Trafficking and Localization of STEVOR Proteins in Three Stages of the Plasmodium falciparum Life Cycle L McRobert, P Preiser, S Sharp, W Jarra, M Kaviratne, MC Taylor, L Renia, ... Infection and immunity 72 (11), 6597-6602, 2004 | 109 | 2004 |
A New Experimental Model for Assessing Drug Efficacy against Trypanosoma cruzi Infection Based on Highly Sensitive In Vivo Imaging MD Lewis, AF Francisco, MC Taylor, JM Kelly Journal of biomolecular screening 20 (1), 36-43, 2015 | 106 | 2015 |
Iron metabolism in trypanosomatids, and its crucial role in infection MC Taylor, JM Kelly Parasitology 137 (6), 899-917, 2010 | 106 | 2010 |
Control of VSG gene expression sites in Trypanosoma brucei P Borst, W Bitter, PA Blundell, I Chaves, M Cross, H Gerrits, ... Molecular and biochemical parasitology 91 (1), 67-76, 1998 | 106 | 1998 |
TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the … SR Wilkinson, MC Taylor, S Touitha, IL Mauricio, DJ Meyer, JM Kelly Biochemical Journal 364 (3), 787-794, 2002 | 99 | 2002 |
Phenotype of recombinant Leishmania donovani and Trypanosoma cruzi which over‐express trypanothione reductase: Sensitivity towards agents that are thought … JM Kelly, MC Taylor, K Smith, KJ Hunter, AH Fairlamb European Journal of Biochemistry 218 (1), 29-37, 1993 | 97 | 1993 |
Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in … FC Costa, AF Francisco, S Jayawardhana, SG Calderano, MD Lewis, ... PLoS neglected tropical diseases 12 (4), e0006388, 2018 | 94 | 2018 |