Effect of calorie restriction on the metabolic history of chronologically aging yeast AA Goldberg, SD Bourque, P Kyryakov, C Gregg, T Boukh-Viner, A Beach, ... Experimental gerontology 44 (9), 555-571, 2009 | 165 | 2009 |
Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping … AA Goldberg, VR Richard, P Kyryakov, SD Bourque, A Beach, ... Aging (Albany NY) 2 (7), 393, 2010 | 142 | 2010 |
Dynamics and regulation of lipid droplet formation in lipopolysaccharide (LPS)-stimulated microglia A Khatchadourian, SD Bourque, VR Richard, VI Titorenko, D Maysinger Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012 | 137 | 2012 |
Targeted and untargeted proteomics approaches in biomarker development CA Sobsey, S Ibrahim, VR Richard, V Gaspar, G Mitsa, V Lacasse, ... Proteomics 20 (9), 1900029, 2020 | 134 | 2020 |
Caloric restriction extends yeast chronological lifespan by altering a pattern of age-related changes in trehalose concentration P Kyryakov, A Beach, VR Richard, MT Burstein, A Leonov, S Levy, ... Frontiers in physiology 3, 256, 2012 | 91 | 2012 |
A novel function of lipid droplets in regulating longevity AA Goldberg, SD Bourque, P Kyryakov, T Boukh-Viner, C Gregg, A Beach, ... Biochemical Society Transactions 37 (5), 1050-1055, 2009 | 85 | 2009 |
A unique morphological phenotype in chemoresistant triple-negative breast cancer reveals metabolic reprogramming and PLIN4 expression as a molecular vulnerability I Sirois, A Aguilar-Mahecha, J Lafleur, E Fowler, V Vu, M Scriver, ... Molecular Cancer Research 17 (12), 2492-2507, 2019 | 82 | 2019 |
Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid … VR Richard, A Leonov, A Beach, MT Burstein, O Koupaki, A Gomez-Perez, ... Aging (Albany NY) 5 (4), 234, 2013 | 76 | 2013 |
Integration of peroxisomes into an endomembrane system that governs cellular aging A Beach, MT Burstein, VR Richard, A Leonov, S Levy, VI Titorenko Frontiers in Physiology 3, 283, 2012 | 64 | 2012 |
Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from “liponecrosis”, a previously unknown form of programmed cell death S Sheibani, V Richard, A Beach, A Leonov, R Feldman, S Mattie, ... Cell Cycle 13 (1), 138-147, 2014 | 57 | 2014 |
Lithocholic acid extends longevity of chronologically aging yeast only if added at certain critical periods of their lifespan MT Burstein, P Kyryakov, A Beach, VR Richard, O Koupaki, ... Cell Cycle 11 (18), 3443-3462, 2012 | 55 | 2012 |
Mitochondrial membrane lipidome defines yeast longevity A Beach, VR Richard, A Leonov, MT Burstein, SD Bourque, O Koupaki, ... Aging (Albany NY) 5 (7), 551, 2013 | 49 | 2013 |
Mechanism of liponecrosis, a distinct mode of programmed cell death VR Richard, A Beach, A Piano, A Leonov, R Feldman, MT Burstein, ... Cell Cycle 13 (23), 3707-3726, 2014 | 48 | 2014 |
Lithocholic bile acid accumulated in yeast mitochondria orchestrates a development of an anti-aging cellular pattern by causing age-related changes in cellular proteome A Beach, VR Richard, S Bourque, T Boukh-Viner, P Kyryakov, ... Cell Cycle 14 (11), 1643-1656, 2015 | 42 | 2015 |
Early prediction of COVID-19 patient survival by targeted plasma multi-omics and machine learning VR Richard, C Gaither, R Popp, D Chaplygina, A Brzhozovskiy, ... Molecular & Cellular Proteomics 21 (10), 2022 | 30 | 2022 |
Molecular phenotyping of laboratory mouse strains using 500 multiple reaction monitoring mass spectrometry plasma assays SA Michaud, NJ Sinclair, H Pětrošová, AL Palmer, AJ Pistawka, S Zhang, ... Communications biology 1 (1), 78, 2018 | 26 | 2018 |
Caloric restriction delays yeast chronological aging by remodeling carbohydrate and lipid metabolism, altering peroxisomal and mitochondrial functionalities, and postponing the … A Arlia-Ciommo, A Leonov, A Beach, VR Richard, SD Bourque, ... Oncotarget 9 (22), 16163, 2018 | 24 | 2018 |
Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation AMY Zhang, YH Xia, JSH Lin, KH Chu, WCK Wang, TJJ Ruiter, JCC Yang, ... Cell Metabolism 35 (12), 2119-2135. e5, 2023 | 20 | 2023 |
An online 2D-reversed-phase–Reversed-phase chromatographic method for sensitive and robust plasma protein quantitation VR Richard, D Domanski, AJ Percy, CH Borchers Journal of proteomics 168, 28-36, 2017 | 20 | 2017 |
Metabolomic and lipidomic analyses of chronologically aging yeast VR Richard, SD Bourque, VI Titorenko Yeast Genetics: Methods and Protocols, 359-373, 2014 | 19 | 2014 |