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Patrick Kwok Shing Ng
Patrick Kwok Shing Ng
The Jackson Laboratory For Genomic Medicine
Verified email at jax.org
Title
Cited by
Cited by
Year
Comprehensive molecular profiling of lung adenocarcinoma
Cancer Genome Atlas Research Network
Nature 511 (7511), 543-550, 2014
31712014
Comprehensive genomic characterization of head and neck squamous cell carcinomas
Cancer Genome Atlas Network
Nature 517 (7536), 576-582, 2015
26042015
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
15932018
Frequent Mutation of the PI3K Pathway in Head and Neck Cancer Defines Predictive BiomarkersMutation of PI3K Pathway in Head and Neck Cancer
VWY Lui, ML Hedberg, H Li, BS Vangara, K Pendleton, Y Zeng, Y Lu, ...
Cancer discovery 3 (7), 761-769, 2013
5692013
A pan-cancer proteomic perspective on The Cancer Genome Atlas
R Akbani, PKS Ng, HMJ Werner, M Shahmoradgoli, F Zhang, Z Ju, W Liu, ...
Nature communications 5 (1), 1-15, 2014
4472014
A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations
Y Zhang, PKS Ng, M Kucherlapati, F Chen, Y Liu, YH Tsang, ...
Cancer Cell 31 (6), 820-832. e3, 2017
3672017
Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer
Y Wang, X Xu, D Maglic, MT Dill, K Mojumdar, PKS Ng, KJ Jeong, ...
Cell reports 25 (5), 1304-1317. e5, 2018
2272018
The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens
TF Chan, KM Ji, AKY Yim, XY Liu, JW Zhou, RQ Li, KY Yang, J Li, M Li, ...
Journal of Allergy and Clinical Immunology 135 (2), 539-548, 2015
1732015
Systematic Functional Annotation of Somatic Mutations in Cancer
PKS Ng, J Li, KJ Jeong, S Shao, H Chen, YH Tsang, S Sengupta, Z Wang, ...
Cancer cell 33 (3), 450-462. e10, 2018
1592018
Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers
C Sun, Y Fang, J Yin, J Chen, Z Ju, D Zhang, X Chen, CP Vellano, ...
Science translational medicine 9 (392), 2017
1552017
Cloning and expression analysis of two distinct HIF-alpha isoforms–gcHIF-1alpha and gcHIF-4alpha–from the hypoxia-tolerant grass carp, Ctenopharyngodon idellus
SHW Law, RSS Wu, PKS Ng, RMK Yu, RYC Kong
BMC molecular biology 7 (1), 1-13, 2006
1442006
Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer
VWY Lui, ND Peyser, PKS Ng, J Hritz, Y Zeng, Y Lu, H Li, L Wang, ...
Proceedings of the National Academy of Sciences 111 (3), 1114-1119, 2014
952014
A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell CarcinomaPI3K Pathway Inhibition …
T Mazumdar, LA Byers, PKS Ng, GB Mills, S Peng, L Diao, YH Fan, ...
Molecular cancer therapeutics 13 (11), 2738-2750, 2014
812014
Naturally occurring neomorphic pik3r1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors
LWT Cheung, S Yu, D Zhang, J Li, PKS Ng, N Panupinthu, S Mitra, Z Ju, ...
Cancer cell 26 (4), 479-494, 2014
782014
RET fusion as a novel driver of medullary thyroid carcinoma
EG Grubbs, PKS Ng, J Bui, NL Busaidy, K Chen, JE Lee, X Lu, H Lu, ...
The Journal of Clinical Endocrinology & Metabolism 100 (3), 788-793, 2015
712015
Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death
VWY Lui, EYL Wong, K Ho, PKS Ng, CPY Lau, SKW Tsui, CM Tsang, ...
Oncogene 30 (9), 1127-1134, 2011
652011
Hypoxia induces telomerase reverse transcriptase (TERT) gene expression in non-tumor fish tissues in vivo: the marine medaka (Oryzias melastigma) model
RMK Yu, EXH Chen, RYC Kong, PKS Ng, HOL Mok, DWT Au
BMC Molecular Biology 7 (1), 1-12, 2006
642006
Enhancement of hypoxia-induced gene expression in fish liver by the aryl hydrocarbon receptor (AhR) ligand, benzo [a] pyrene (BaP)
RMK Yu, PKS Ng, T Tan, DLH Chu, RSS Wu, RYC Kong
Aquatic toxicology 90 (3), 235-242, 2008
602008
Characterization of a hypoxia-responsive leptin receptor (omLepR L) cDNA from the marine medaka (Oryzias melastigma)
MML Wong, RMK Yu, PKS Ng, SHW Law, AKC Tsang, RYC Kong
Marine pollution bulletin 54 (6), 797-803, 2007
592007
AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive rats
Q Yang, HM Xue, WT Wong, XY Tian, Y Huang, SKW Tsui, PKS Ng, ...
British journal of pharmacology 163 (5), 1078-1085, 2011
492011
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