Patrick Kwok Shing Ng
Patrick Kwok Shing Ng
The Jackson Laboratory For Genomic Medicine
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Comprehensive molecular profiling of lung adenocarcinoma
Cancer Genome Atlas Research Network
Nature 511 (7511), 543-550, 2014
Comprehensive genomic characterization of head and neck squamous cell carcinomas
Cancer Genome Atlas Network
Nature 517 (7536), 576-582, 2015
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
Frequent Mutation of the PI3K Pathway in Head and Neck Cancer Defines Predictive BiomarkersMutation of PI3K Pathway in Head and Neck Cancer
VWY Lui, ML Hedberg, H Li, BS Vangara, K Pendleton, Y Zeng, Y Lu, ...
Cancer discovery 3 (7), 761-769, 2013
A pan-cancer proteomic perspective on The Cancer Genome Atlas
R Akbani, PKS Ng, HMJ Werner, M Shahmoradgoli, F Zhang, Z Ju, W Liu, ...
Nature communications 5 (1), 1-15, 2014
A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations
Y Zhang, PKS Ng, M Kucherlapati, F Chen, Y Liu, YH Tsang, ...
Cancer Cell 31 (6), 820-832. e3, 2017
Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer
Y Wang, X Xu, D Maglic, MT Dill, K Mojumdar, PKS Ng, KJ Jeong, ...
Cell reports 25 (5), 1304-1317. e5, 2018
The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens
TF Chan, KM Ji, AKY Yim, XY Liu, JW Zhou, RQ Li, KY Yang, J Li, M Li, ...
Journal of Allergy and Clinical Immunology 135 (2), 539-548, 2015
Systematic Functional Annotation of Somatic Mutations in Cancer
PKS Ng, J Li, KJ Jeong, S Shao, H Chen, YH Tsang, S Sengupta, Z Wang, ...
Cancer cell 33 (3), 450-462. e10, 2018
Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers
C Sun, Y Fang, J Yin, J Chen, Z Ju, D Zhang, X Chen, CP Vellano, ...
Science translational medicine 9 (392), 2017
Cloning and expression analysis of two distinct HIF-alpha isoforms–gcHIF-1alpha and gcHIF-4alpha–from the hypoxia-tolerant grass carp, Ctenopharyngodon idellus
SHW Law, RSS Wu, PKS Ng, RMK Yu, RYC Kong
BMC molecular biology 7 (1), 1-13, 2006
Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer
VWY Lui, ND Peyser, PKS Ng, J Hritz, Y Zeng, Y Lu, H Li, L Wang, ...
Proceedings of the National Academy of Sciences 111 (3), 1114-1119, 2014
A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell CarcinomaPI3K Pathway Inhibition …
T Mazumdar, LA Byers, PKS Ng, GB Mills, S Peng, L Diao, YH Fan, ...
Molecular cancer therapeutics 13 (11), 2738-2750, 2014
Naturally occurring neomorphic pik3r1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors
LWT Cheung, S Yu, D Zhang, J Li, PKS Ng, N Panupinthu, S Mitra, Z Ju, ...
Cancer cell 26 (4), 479-494, 2014
RET fusion as a novel driver of medullary thyroid carcinoma
EG Grubbs, PKS Ng, J Bui, NL Busaidy, K Chen, JE Lee, X Lu, H Lu, ...
The Journal of Clinical Endocrinology & Metabolism 100 (3), 788-793, 2015
Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death
VWY Lui, EYL Wong, K Ho, PKS Ng, CPY Lau, SKW Tsui, CM Tsang, ...
Oncogene 30 (9), 1127-1134, 2011
Hypoxia induces telomerase reverse transcriptase (TERT) gene expression in non-tumor fish tissues in vivo: the marine medaka (Oryzias melastigma) model
RMK Yu, EXH Chen, RYC Kong, PKS Ng, HOL Mok, DWT Au
BMC Molecular Biology 7 (1), 1-12, 2006
Enhancement of hypoxia-induced gene expression in fish liver by the aryl hydrocarbon receptor (AhR) ligand, benzo [a] pyrene (BaP)
RMK Yu, PKS Ng, T Tan, DLH Chu, RSS Wu, RYC Kong
Aquatic toxicology 90 (3), 235-242, 2008
Characterization of a hypoxia-responsive leptin receptor (omLepR L) cDNA from the marine medaka (Oryzias melastigma)
MML Wong, RMK Yu, PKS Ng, SHW Law, AKC Tsang, RYC Kong
Marine pollution bulletin 54 (6), 797-803, 2007
AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive rats
Q Yang, HM Xue, WT Wong, XY Tian, Y Huang, SKW Tsui, PKS Ng, ...
British journal of pharmacology 163 (5), 1078-1085, 2011
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