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Holly A R Giles
Holly A R Giles
Verified email at cam.ac.uk
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Quantification of differential transcription factor activity and multiomics-based classification into activators and repressors: diffTF
I Berest, C Arnold, A Reyes-Palomares, G Palla, KD Rasmussen, H Giles, ...
Cell Reports 29 (10), 3147-3159. e12, 2019
1042019
Multi-omics reveals clinically relevant proliferative drive associated with mTOR-MYC-OXPHOS activity in chronic lymphocytic leukemia
J Lu, E Cannizzaro, F Meier-Abt, S Scheinost, PM Bruch, HAR Giles, ...
Nature Cancer, 1-12, 2021
412021
Drug‐microenvironment perturbations reveal resistance mechanisms and prognostic subgroups in CLL
PM Bruch, HAR Giles, C Kolb, SA Herbst, T Becirovic, T Roider, J Lu, ...
Molecular Systems Biology 18 (8), e10855, 2022
112022
Ex-Vivo Drug Response Profiling for Tailoring Treatment in Hematologic Malignancies: The Prospective Non-Interventional SMART-Trial
N Liebers, PM Bruch, A Gambietz, H Giles, J Lu, M Knoll, C Kolb, ...
Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019
52019
Systematic Investigation of Microenvironmental Drug Resistance Mechanisms in Chronic Lymphocytic Leukemia
PM Bruch, H Giles, C Kolb, S Rabe, T Roider, M Knoll, M Kriegsmann, ...
Blood, The Journal of the American Society of Hematology 134 (Supplement_1 …, 2019
22019
Chronic Lymphocytic Leukaemia and the Tumour Microenvironment: A multi-omics investigation of interactions between genetic aberrations and external signals and their impact on …
HAR Giles
2022
Clinical implementation of an ex-vivo drug response profiling for hematologic malignancies: results of an interim analysis of the prospective non-interventional SMART trial
N Liebers, PM Bruch, T Terzer, J Lu, H Giles, M Knoll, C Kolb, A Lenze, ...
ONCOLOGY RESEARCH AND TREATMENT 43 (SUPPL 4), 248-249, 2020
2020
Drug cytokine interaction map in chronic lymphocytic leukemia
PM Bruch, H Giles, C Kolb, S Rabe, T Roider, M Knoll, M Kriegsmann, ...
ONCOLOGY RESEARCH AND TREATMENT 42, 221-221, 2019
2019
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