Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non–Small Cell Lung Cancer Cells S Sohoni, P Ghosh, T Wang, SP Kalainayakan, C Vidal, S Dey, ... Cancer research 79 (10), 2511-2525, 2019 | 60 | 2019 |
Cyclopamine tartrate, an inhibitor of Hedgehog signaling, strongly interferes with mitochondrial function and suppresses aerobic respiration in lung cancer cells MM Alam, S Sohoni, SP Kalainayakan, M Garrossian, L Zhang BMC cancer 16, 1-10, 2016 | 44 | 2016 |
Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry TT Nguyen, DH Shin, S Sohoni, SK Singh, Y Rivera-Molina, H Jiang, ... Journal for ImmunoTherapy of Cancer 10 (7), 2022 | 25 | 2022 |
Cyclopamine tartrate, a modulator of hedgehog signaling and mitochondrial respiration, effectively arrests lung tumor growth and progression SP Kalainayakan, P Ghosh, S Dey, KE Fitzgerald, S Sohoni, PC Konduri, ... Scientific reports 9 (1), 1405, 2019 | 24 | 2019 |
Elevated Mitochondrial and Heme Function as Hallmarks for Non-Small Cell Lung Cancers C Vidal, S Sohoni, S Zhang J Mol Biomark Diagn 7 (305), 2, 2016 | 2 | 2016 |
Chimeric oncolytic adenovirus evades neutralizing antibodies from human patients and exhibits enhanced anti-glioma efficacy in immunized mice DH Shin, H Jiang, AG Gillard, D Kim, X Fan, SK Singh, TT Nguyen, ... Molecular Therapy 32 (3), 722-733, 2024 | 1 | 2024 |
DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis J Sanceau, L Poupel, C Joubel, I Lagoutte, S Caruso, S Pinto, ... Molecular Therapy, 2024 | 1 | 2024 |
Evaluating the efficacy of limiting heme availability on growth and progression of lung tumor P Ghosh, SP Kalainayakan, S Dey, S Sohoni, L Zhang Cancer Research 77 (13_Supplement), 1500-1500, 2017 | 1 | 2017 |
Changes in the gut microbiota associated with oncolytic virotherapy efficacy in a gastric cancer murine model NM Melendez-Vazquez, S Sohoni, A Van Wieren, J Fueyo, ... Cancer Research 83 (7_Supplement), 5894-5894, 2023 | | 2023 |
Redirection of anti-virus immunity towards anti-tumor immunity using nanoparticle-induced immune tolerance for oncolytic adenovirus therapy DH Shin, H Jiang, D Kim, TT Nguyen, S Sohoni, X Fan, Y Yi, ... Cancer Research 82 (12_Supplement), 3559-3559, 2022 | | 2022 |
RNA-seq analyses reveal remodeling of tumor microenvironment and reversal of glioma resistance to oncolytic viruses by targeting immunometabolism TT Nguyen, DH Shin, S Sohoni, SK Singh, Y Rivera-Molina, H Jiang, ... Cancer Research 82 (12_Supplement), 4184-4184, 2022 | | 2022 |
ARMED ONCOLYTIC ADENOVIRUS AS EXPERIMENTAL THERAPY FOR PEDIATRIC MALIGNANT GLIOMAS S Gupta, V Laspidea, J Fueyo, W Zaky, O Becher, T Nguyen, DH Shin, ... PEDIATRIC BLOOD & CANCER 69, 2022 | | 2022 |
Armed Oncolytic Adenovirus as Experimental Therapy For Pediatric Malignant Gliomas MMA Sumit Gupta, MD, Virginia Laspidea, Juan Fueyo, Wafik Zaky, Oren Becher ... ASPHO Conference, 2022 | | 2022 |
Viroimmunotherapy for solid tumors results in local and abscopal anti-cancer effects and the remodeling of tumor microenvironment GMC Van Wieren AC, Sohoni S, Nguyen T, Ossimetha A, Rivera-Molina Y, Jiang H ... AACR2022, 2022 | | 2022 |
610 Sustainable regression of disseminated solid tumors mediated by in situ combinational treatment with adoptive T cell therapy and oncolytic adenovirus Delta-24-RGDOX H Jiang, DH Shin, S Sohoni, T Nguyen, Y Yi, X Fan, J Gumin, S Singh, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | | 2021 |
Gut bugs matter to viroimmunotherapy: bacterial changes associated to the efficacy of Delta-24-RGDOX against glioblastoma F Melendez-Vazquez, N.M. , Nguyen, T. , Sohoni, S. , Ossimetha, A. , Fueyo ... 63rd Puerto Rico Society of Microbiologists Annual Meeting ISME-LAT 2021, 2021 | | 2021 |
Oncolytic adenovirus Delta-24-RGDOX collaborates with adoptive cell therapy to sustain anti-tumor immunity H Jiang, TT Nguyen, DH Shin, SS Sohoni, S Gupta, Y Yi, X Fan, ... Cancer Research 81 (13_Supplement), 1579-1579, 2021 | | 2021 |
Evasion of neutralizing antibodies and enhanced anti-tumor effects of hexon-modified Delta-24-RGD oncolytic adenovirus DH Shin, TT Nguyen, H Jiang, X Fan, Y Yi, SS Sohoni, S Gupta, ... Cancer Research 81 (13_Supplement), 1912-1912, 2021 | | 2021 |
Inhibition of the IDO-Kyn-AhR cascade optimizes virotherapy in glioblastoma and depends on CD4 T-cell activation TT Nguyen, DH Shin, H Jiang, DA Wainwright, S Sohoni, S Gupta, ... Cancer Research 81 (13_Supplement), 1785-1785, 2021 | | 2021 |
Armed oncolytic virus for treatment of pediatric diffuse intrinsic pontine glioma S Gupta, V Laspidea, J Fueyo, O Becher, T Nguyen, DH Shin, H Jiang, ... Cancer Research 81 (13_Supplement), 3053-3053, 2021 | | 2021 |