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Prashant Raj Bhattarai
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A CD45-targeted antibody-drug conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation in mice
A Saha, S Hyzy, T Lamothe, K Hammond, N Clark, L Lanieri, P Bhattarai, ...
Blood, The Journal of the American Society of Hematology 139 (11), 1743-1759, 2022
262022
Design and In Vitro Evaluation of Bispecific Complexes and Drug Conjugates of Anticancer Peptide, LyP-1 in Human Breast Cancer
SS Timur, P Bhattarai, RN Gürsoy, İ Vural, BA Khaw
Pharmaceutical research 34, 352-364, 2017
162017
A single dose of a novel anti-human CD117-amanitin antibody drug conjugate (ADC) engineered for a short half-life provides dual conditioning and anti-leukemic activity and …
L Lanieri, TL Lamothe, O Miske, SM McDonough, GN Sarma, P Bhattarai, ...
Blood 136, 47-48, 2020
62020
Imaging doxorubicin and polymer-drug conjugates of doxorubicin-induced cardiotoxicity with bispecific anti-myosin-anti-DTPA antibody and Tc-99m-labeled polymers
R Panwar, P Bhattarai, V Patil, K Gada, S Majewski, BA Khaw
Journal of Nuclear Cardiology 26, 1327-1344, 2019
62019
CD117 Antibody Drug Conjugate-Based Conditioning Allows for Efficient Engraftment of Gene-Modified CD34+ Cells in a Rhesus Gene Therapy Model
N Uchida, U Stasula, M Hinds, P Germino-Watnick, AE Krouse, NS Linde, ...
Blood 138, 560, 2021
42021
An in vitro demonstration of overcoming drug resistance in SKOV3 TR and MCF7 ADR with targeted delivery of polymer pro-drug conjugates
P Bhattarai, D Vance, A Hatefi, BA Khaw
Journal of drug targeting 25 (5), 436-450, 2017
32017
A novel targeted approach to achieve immune system reset: CD45-Targeted antibody drug conjugates enable autologous HSCT and ameliorate disease in preclinical autoimmune disease …
GO Gillard, JL Proctor, ML Brooks, TL Lamothe, SL Hyzy, SM McDonough, ...
Biology of Blood and Marrow Transplantation 26 (3), S307-S308, 2020
22020
A novel targeted approach to achieve immune system reset: CD45-targeted antibody drug conjugates enable autologous HSCT, ameliorate disease in autoimmune models, potently kill …
GO Gillard, JL Proctor, ML Brooks, TL Lamothe, SL Hyzy, O Mikse, ...
Blood 134, 3208, 2019
22019
Administration of a CD45 antibody drug conjugate as a novel, targeted approach to achieve immune system reset: A single dose of CD45-targeted ADC safely conditions for …
GR Gillard, J Proctor, M Brooks, T Lamothe, S Hyzy, S McDonough, ...
ARTHRITIS & RHEUMATOLOGY 71, 2019
22019
OP0307 A novel targeted approach to achieve immune system reset: CD45-targeted antibody drug conjugates ameliorate disease in preclinical autoimmune disease models and enable …
G Gillard, J Proctor, S Hyzy, O Mikse, T Lamothe, S McDonough, N Clark, ...
Annals of the Rheumatic Diseases 79 (Suppl 1), 190-191, 2020
12020
Single Agent CD117-Targeted Antibody Drug Conjugate in Combination with Lympho-Depleting Antibodies Enables Allogenic Hematopoietic Stem Cell Transplantation in Mice without …
L Lanieri, TL Lamothe, P raj Bhattarai, R Palchaudhuri, LM Olson
2022 Tandem Meetings| Transplantation & Cellular Therapy Meetings of ASTCT …, 2022
2022
A Sngle Injection of CD117 Antibody-Drug Conjugate Allows for Efficient Engraftment of Gene-Modified CD34+ Cells in a Rhesus Gene Therapy Model
N Uchida, U Stasula, M Hinds, P Germino-Watnick, AE Krouse, NS Linde, ...
MOLECULAR THERAPY 30 (4), 385-385, 2022
2022
CD117 Antibody Drug Conjugate-Based Conditioning Enables Efficient Engraftment of Gene-Modified CD34+ Cells in a Rhesus Gene Therapy Model
R Palchaudhuri, N Uchida, U Stasula, M Hinds, P Germino-Watnick, ...
Transplantation and Cellular Therapy 28 (3), S238, 2022
2022
Single Agent CD117-Targeted Antibody Drug Conjugate in Combination with Lymphodepleting Antibodies Enables Allogenic Hematopoietic Stem Cell Transplantation in Mice without …
L Lanieri, T Lamothe, P Bhattarai, R Palchaudhuri, L Olson
Blood 138, 1682, 2021
2021
A Single Dose of a Novel Anti-Human CD117-Amanitin Antibody Drug Conjugate (ADC) Engineered for a Short Half-Life Provides Dual Conditioning and Anti-Leukemia Activity and …
L Lanieri, TL Lamothe, O Mikse, SM McDonough, GN Sarma, ...
2021 TCT| Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR, 2021
2021
A Single Dose of a Novel Anti-Human Short Half-Life Engineered CD45-Targeted Antibody-Drug Conjugate (ADC) Is Cytoreductive on Patient-Derived Tumors and Extends Survival …
JL Proctor, GO Gillard, O Mikse, L Lanieri, TL Lamothe, ML Brooks, L Kien, ...
Biology of Blood and Marrow Transplantation 26 (3), S96, 2020
2020
Changes in Cardiac Isomyosin Composition in an Iron Loading Anemia Rat Model
WT Cheng, NY Kim, P Bhattarai, M Han, AV Menon, J Kim, BA Khaw
Journal of Cardiology and Cardiovascular Sciences 3 (4), 2019
2019
Methods and compositions for overcoming drug-resistance in cancer by targeted delivery of pro-drug-nano-polymers
B Khaw, P Bhattarai
US Patent App. 15/196,968, 2016
2016
Methods and compositions for overcoming drug-resistance in cancer by targeted delivery of pro-drug-nano-polymers
B Khaw, P Bhattarai
US Patent App. 15/135,543, 2016
2016
Immuno-molecular quantitation of β-isomyosin in Belgrade rats, a model of hypertrophic cardiomyopathy.
BA Khaw, WT Chang, P Bhattarai, M Han, J Kim
Journal of Nuclear Medicine 57 (supplement 2), 1226-1226, 2016
2016
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