Understanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors RK Bedi, C Patel, V Mishra, H Xiao, RY Yada, P Bhaumik Scientific reports 6, 31420, 2016 | 30 | 2016 |
Advancements in macromolecular crystallography: from past to present I Rathore, V Mishra, P Bhaumik Emerging Topics in Life Sciences 5 (1), 127-149, 2021 | 17 | 2021 |
Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins–biochemical and structural insights V Mishra, I Rathore, A Arekar, LK Sthanam, H Xiao, Y Kiso, S Sen, ... The FEBS journal 285 (16), 3077-3096, 2018 | 12 | 2018 |
Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in … P Kesari, A Deshmukh, N Pahelkar, AB Suryawanshi, I Rathore, V Mishra, ... Protein Science 31 (4), 882-899, 2022 | 11 | 2022 |
Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2 AL Parui, V Mishra, S Dutta, P Bhaumik, K Bose Structure 30 (9), 1307-1320. e5, 2022 | 5 | 2022 |
Activation mechanism of plasmepsins, pepsin‐like aspartic proteases from Plasmodium, follows a unique trans‐activation pathway I Rathore, V Mishra, C Patel, H Xiao, A Gustchina, A Wlodawer, RY Yada, ... The FEBS journal 288 (2), 678-698, 2021 | 5 | 2021 |
Structure-based Designing of Inhibitors against Plasmepsins from Plasmodium Falciparum V Mishra, I Rathore, A Arekar, LK Sthanam, RK Bedi, C Patel, ... Available at SSRN 3535504, 2020 | 1 | 2020 |
Full wwPDB X-ray Structure Validation Report i○ I Rathore, V Mishra, P Bhaumik | 1* | |
Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes S Palani, Y Machida, JR Alvey, V Mishra, AL Welter, G Cui, B Bragantini, ... Nature Communications 15 (1), 2064, 2024 | | 2024 |
Inhibition of Plasmodium falciparum plasmepsins by drugs targeting HIV-1 protease: A way forward for antimalarial drug discovery V Mishra, A Deshmukh, I Rathore, S Chakraborty, S Patankar, ... Current Research in Structural Biology 7, 100128, 2024 | | 2024 |
Structural insights of plasmepsin X from Plasmodium falciparum uncovering a novel inactivation mechanism of zymogen A Deshmukh, P Kesari, N Pahelkar, A Suryawanshi, I Rathore, V Mishra, ... Acta Crystallographica Section A: Foundations and Advances 78, a388-a389, 2022 | | 2022 |
Structures of plasmepsin X from P. falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme P Kesari, A Deshmukh, N Pahelkar, AB Suryawanshi, I Rathore, V Mishra, ... bioRxiv, 2021.09. 24.460453, 2021 | | 2021 |
Molecular insights into the inhibition of plasmepsins by HIV-1 protease inhibitors: Implications for antimalarial drug discovery V Mishra, I Rathore, A Deshmukh, S Patankar, A Gustchina, A Wlodawer, ... bioRxiv, 2021 | | 2021 |
Structural Characterization of Aspartic Proteases Involved in Invasion and Egress of Apicomplexan Pathogens P. Falciparum and T. gondii P Kesari, A Deshmukh, N Pahelkar, I Rathore, V Mishra, H Xiao, ... Falciparum and T. gondii (February 10, 2020), 2020 | | 2020 |
Understanding the Activation Mechanism of Proplasmepsins and the Catalytic Mechanism of Aspartic Proteases With Implications in Drug Development I Rathore, V Mishra, C Patel, H Xiao, A Gustchina, K Hidaka, A Wlodawer, ... Available at SSRN 3535503, 2020 | | 2020 |
Structure-based drug designing against Plasmepsins from Plasmodium falciparum V Mishra, I Rathore, A Arekar, H Xiao, R Yada, A Wlodawer, A Gustchina, ... ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 73, C50-C50, 2017 | | 2017 |
Structural insights into the mechanism of Plasmepsins from P. falciparum I Rathore, V Mishra, C Patel, H Xiao, R Yada, A Gustchina, A Wlodawer, ... ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 73, C166-C166, 2017 | | 2017 |
Structure-based drug designing against Plasmepsins from Plasmodium falciparum V Mishra, I Rathore, A Arekar, H Xiao, R Yada, A Wlodawer, A Gustchina, ... ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 70, C50-C50, 2014 | | 2014 |
Structural insights into the mechanism of Plasmepsins from P. falciparum I Rathore, V Mishra, C Patel, H Xiao, R Yada, A Gustchina, A Wlodawer, ... ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 70, C166-C166, 2014 | | 2014 |