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Vandana Mishra
Vandana Mishra
Indian Institute of Technology Bombay
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Year
Understanding the structural basis of substrate recognition by Plasmodium falciparum plasmepsin V to aid in the design of potent inhibitors
RK Bedi, C Patel, V Mishra, H Xiao, RY Yada, P Bhaumik
Scientific reports 6, 31420, 2016
302016
Advancements in macromolecular crystallography: from past to present
I Rathore, V Mishra, P Bhaumik
Emerging Topics in Life Sciences 5 (1), 127-149, 2021
172021
Deciphering the mechanism of potent peptidomimetic inhibitors targeting plasmepsins–biochemical and structural insights
V Mishra, I Rathore, A Arekar, LK Sthanam, H Xiao, Y Kiso, S Sen, ...
The FEBS journal 285 (16), 3077-3096, 2018
122018
Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in …
P Kesari, A Deshmukh, N Pahelkar, AB Suryawanshi, I Rathore, V Mishra, ...
Protein Science 31 (4), 882-899, 2022
112022
Inter-subunit crosstalk via PDZ synergistically governs allosteric activation of proapoptotic HtrA2
AL Parui, V Mishra, S Dutta, P Bhaumik, K Bose
Structure 30 (9), 1307-1320. e5, 2022
52022
Activation mechanism of plasmepsins, pepsin‐like aspartic proteases from Plasmodium, follows a unique trans‐activation pathway
I Rathore, V Mishra, C Patel, H Xiao, A Gustchina, A Wlodawer, RY Yada, ...
The FEBS journal 288 (2), 678-698, 2021
52021
Structure-based Designing of Inhibitors against Plasmepsins from Plasmodium Falciparum
V Mishra, I Rathore, A Arekar, LK Sthanam, RK Bedi, C Patel, ...
Available at SSRN 3535504, 2020
12020
Full wwPDB X-ray Structure Validation Report i○
I Rathore, V Mishra, P Bhaumik
1*
Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes
S Palani, Y Machida, JR Alvey, V Mishra, AL Welter, G Cui, B Bragantini, ...
Nature Communications 15 (1), 2064, 2024
2024
Inhibition of Plasmodium falciparum plasmepsins by drugs targeting HIV-1 protease: A way forward for antimalarial drug discovery
V Mishra, A Deshmukh, I Rathore, S Chakraborty, S Patankar, ...
Current Research in Structural Biology 7, 100128, 2024
2024
Structural insights of plasmepsin X from Plasmodium falciparum uncovering a novel inactivation mechanism of zymogen
A Deshmukh, P Kesari, N Pahelkar, A Suryawanshi, I Rathore, V Mishra, ...
Acta Crystallographica Section A: Foundations and Advances 78, a388-a389, 2022
2022
Structures of plasmepsin X from P. falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme
P Kesari, A Deshmukh, N Pahelkar, AB Suryawanshi, I Rathore, V Mishra, ...
bioRxiv, 2021.09. 24.460453, 2021
2021
Molecular insights into the inhibition of plasmepsins by HIV-1 protease inhibitors: Implications for antimalarial drug discovery
V Mishra, I Rathore, A Deshmukh, S Patankar, A Gustchina, A Wlodawer, ...
bioRxiv, 2021
2021
Structural Characterization of Aspartic Proteases Involved in Invasion and Egress of Apicomplexan Pathogens P. Falciparum and T. gondii
P Kesari, A Deshmukh, N Pahelkar, I Rathore, V Mishra, H Xiao, ...
Falciparum and T. gondii (February 10, 2020), 2020
2020
Understanding the Activation Mechanism of Proplasmepsins and the Catalytic Mechanism of Aspartic Proteases With Implications in Drug Development
I Rathore, V Mishra, C Patel, H Xiao, A Gustchina, K Hidaka, A Wlodawer, ...
Available at SSRN 3535503, 2020
2020
Structure-based drug designing against Plasmepsins from Plasmodium falciparum
V Mishra, I Rathore, A Arekar, H Xiao, R Yada, A Wlodawer, A Gustchina, ...
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 73, C50-C50, 2017
2017
Structural insights into the mechanism of Plasmepsins from P. falciparum
I Rathore, V Mishra, C Patel, H Xiao, R Yada, A Gustchina, A Wlodawer, ...
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 73, C166-C166, 2017
2017
Structure-based drug designing against Plasmepsins from Plasmodium falciparum
V Mishra, I Rathore, A Arekar, H Xiao, R Yada, A Wlodawer, A Gustchina, ...
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 70, C50-C50, 2014
2014
Structural insights into the mechanism of Plasmepsins from P. falciparum
I Rathore, V Mishra, C Patel, H Xiao, R Yada, A Gustchina, A Wlodawer, ...
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 70, C166-C166, 2014
2014
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Articles 1–19