| DARK classics in chemical neuroscience: gamma-hydroxybutyrate (GHB) TA Trombley, RA Capstick, CW Lindsley ACS Chemical Neuroscience 11 (23), 3850-3859, 2019 | 16 | 2019 |
| VU6007477, a Novel M1 PAM Based on a Pyrrolo[2,3-b]pyridine Carboxamide Core Devoid of Cholinergic Adverse Events JL Engers, ES Childress, MF Long, RA Capstick, VB Luscombe, HP Cho, ... ACS medicinal chemistry letters 9 (9), 917-922, 2018 | 15 | 2018 |
| Development of VU6019650: A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M5 Muscarinic Acetylcholine Receptor for the … AT Garrison, DL Orsi, RA Capstick, D Whomble, J Li, TR Carter, AS Felts, ... Journal of Medicinal Chemistry 65 (8), 6273-6286, 2022 | 9 | 2022 |
| The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu4 PAM development candidate JD Panarese, DW Engers, YJ Wu, JM Guernon, A Chun, AR Gregro, ... Bioorganic & Medicinal Chemistry Letters 29 (2), 342-346, 2019 | 5 | 2019 |
| Indazole compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction PJ Conn, CW Lindsley, AS Felts, CM Niswender, RA Capstick, ... US Patent 10,508,105, 2019 | 4 | 2019 |
| Discovery of a potent M5 antagonist with improved clearance profile. Part 1: Piperidine amide-based antagonists RA Capstick, D Whomble, DL Orsi, AS Felts, AL Rodriguez, PN Vinson, ... Bioorganic & Medicinal Chemistry Letters 76, 128988, 2022 | 2 | 2022 |
| Development of Potent and Selective Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 2 for the Potential Treatment of Alzheimer’s Disease JS Coleman, RA Capstick, UA Rathnayake, L Parr, S Chang, ... Alzheimer's & Dementia 19, e076916, 2023 | | 2023 |
| Arylsulfonyl derivatives and their use as muscarinic acetylcholine receptor m5 inhibitors AS Felts, HAN Changho, RA Capstick, DL Orsi, DL Whomble, ... US Patent App. 18/002,004, 2023 | | 2023 |
| Competitive and noncompetitive inhibitors of the muscarinic acetylcholine receptor m5 CW Lindsley, CK Jones, PJ Conn, HAN Changho, AS Felts, DL Orsi, ... US Patent App. 17/998,901, 2023 | | 2023 |
| Positive allosteric modulators of the muscarinic acetylcholine receptor m4 CW Lindsley, PJ Conn, DW Engers, S BOLLINGER, JC Tarr, P Spearing, ... | | 2022 |
| Pyridine quinoline compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction PJ Conn, CW Lindsley, AS Felts, CM Niswender, RA Capstick, ... US Patent 11,319,304, 2022 | | 2022 |
| Discovery of structurally distinct tricyclic M4 positive allosteric modulator (PAM) chemotypes–Part 2 MF Long, RA Capstick, PK Spearing, JL Engers, AR Gregro, SR Bollinger, ... Bioorganic & medicinal chemistry letters 53, 128416, 2021 | | 2021 |
| compostos indazol como potencializadores alostéricos de mglur4 e seus usos terapêuticos, bem como composição farmacêutica e método para fabricação de medicamento para potenciar … JP Conn, CW Lindsley, A Felts, CM Niswender, RA Capstick, PK Spearing, ... | | 2020 |
| Compuestos de indazol como potenciadores alostericos mglur4, composiciones y metodos de tratamiento de la disfuncion neurologica PJ Conn, CW Lindsley, A Felts, CM Niswender, RA Capstick, PK Spearing, ... | | 2020 |
| POSITIVE ALLOSTERIC MODULATORS OF THE ACETYLCHOLIN M4 MUSCARINIC RECEPTOR CW Lindsley, DW Engers, PJ CONN, KA Bollinger, R CAPSTICK, ... | | 2020 |
| INDAZOLE COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIALIZERS, COMPOSITIONS, AND METHODS FOR TREATING NEUROLOGICAL DYSFUNCTIONS PJ Conn, CW Lindsley, A FELTS, CM Niswender, RA CAPSTICK, ... | | 2019 |
