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Kun Yuan
Kun Yuan
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Year
Global targeting of functional tyrosines using sulfur-triazole exchange chemistry
HS Hahm, EK Toroitich, AL Borne, JW Brulet, AH Libby, K Yuan, TB Ware, ...
Nature chemical biology 16 (2), 150-159, 2020
1502020
Liganding functional tyrosine sites on proteins using sulfur–triazole exchange chemistry
JW Brulet, AL Borne, K Yuan, AH Libby, KL Hsu
Journal of the American Chemical Society 142 (18), 8270-8280, 2020
592020
Cascade Reaction of Propargyl Amines with AgSCF3, as Well as One-Pot Reaction of Propargyl Amines, AgSCF3, and Di-tert-butyl Peroxide: Access to Allenyl …
L Zhen, K Yuan, X Li, C Zhang, J Yang, H Fan, L Jiang
Organic letters 20 (10), 3109-3113, 2018
342018
Development and biological applications of sulfur–triazole exchange (SuTEx) chemistry
AL Borne, JW Brulet, K Yuan, KL Hsu
RSC chemical biology 2 (2), 322-337, 2021
192021
Direct target site identification of a sulfonyl–triazole covalent kinase probe by LC-MS chemical proteomics
RL McCloud, K Yuan, KE Mahoney, DL Bai, J Shabanowitz, MM Ross, ...
Analytical chemistry 93 (35), 11946-11955, 2021
152021
Predicting small molecule binding pockets on diacylglycerol kinases using chemoproteomics and AlphaFold
R Mendez, M Shaikh, MC Lemke, K Yuan, AH Libby, DL Bai, MM Ross, ...
RSC Chemical Biology 4 (6), 422-430, 2023
12023
Imidazoles are tunable nucleofuges for developing tyrosine‐reactive electrophiles
RJ Grams, K Yuan, MW Founds, ML Ware, MG Pilar, KL Hsu
ChemBioChem, e202400382, 2024
2024
Mapping small molecule binding pockets on lipid kinases using chemoproteomics and AlphaFold
KL Hsu, R Mendez, M Shaikh, M Lemke, K Yuan, A Libby, D Bai, M Ross, ...
Journal of Biological Chemistry 299 (3), S62-S62, 2023
2023
Advances in Activity‐Based Protein Profiling of Functional Tyrosines in Proteomes
JW Brulet, AM Ciancone, K Yuan, KL Hsu
Israel Journal of Chemistry 63 (3-4), e202300001, 2023
2023
Sulfur-heterocycle exchange chemistry and uses thereof
KL Hsu, HS Hahm, EK Toroitich, JW Brulet, AL Borne, AH Libby, K Yuan
US Patent App. 17/441,544, 2022
2022
Exploring ligandability of tyrosines in proteomes using sulfur-triazole exchange chemistry
A Libby, J Brulet, Ku-Lung (Ken) Hsu, A Borne, K Yuan
American Chemical Society SciMeetings 1 (2), 2020
2020
Global targeting of functional (phospho) tyrosines using sulfur-triazole exchange chemistry
KL Hsu, AL Borne, JW Brulet, HS Hahm, EK Toroitich, AH Libby, K Yuan, ...
The Journal of Immunology 204 (1_Supplement), 159.44-159.44, 2020
2020
Sticking a Label on Tyrosine
D Trauner, M Reynders
Synfacts 16 (02), 0218, 2020
2020
Identifying Reactive Sites on Diacylglycerol Kinases for Covalent Binding in Cells
R Mendez, MS Shaikh, MC Lemke, K Yuan, AH Libby, DL Bai, MM Ross, ...
Available at SSRN 4112545, 0
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