Pathophysiology of type 2 diabetes mellitus U Galicia-Garcia, A Benito-Vicente, S Jebari, A Larrea-Sebal, H Siddiqi, ... International journal of molecular sciences 21 (17), 6275, 2020 | 2044 | 2020 |
Surfactant-induced cell toxicity and cell lysis: A study using B16 melanoma cells MA Partearroyo, H Ostolaza, FM Goñi, E Barberá-Guillem Biochemical pharmacology 40 (6), 1323-1328, 1990 | 158 | 1990 |
Familial hypercholesterolemia: the most frequent cholesterol metabolism disorder caused disease A Benito-Vicente, KB Uribe, S Jebari, U Galicia-Garcia, H Ostolaza, ... International journal of molecular sciences 19 (11), 3426, 2018 | 142 | 2018 |
Release of lipid vesicle contents by the bacterial protein toxin α-haemolysin H Ostolaza, B Bartolomé, IO de Zárate, F de la Cruz, FM Goñi Biochimica et Biophysica Acta (BBA)-Biomembranes 1147 (1), 81-88, 1993 | 136 | 1993 |
Glycophorin as a Receptor for Escherichia coliα-Hemolysin in Erythrocytes AL Cortajarena, FM Goñi, H Ostolaza Journal of Biological Chemistry 276 (16), 12513-12519, 2001 | 108 | 2001 |
Statin treatment-induced development of type 2 diabetes: from clinical evidence to mechanistic insights U Galicia-Garcia, S Jebari, A Larrea-Sebal, KB Uribe, H Siddiqi, ... International journal of molecular sciences 21 (13), 4725, 2020 | 103 | 2020 |
Membrane Restructuring by Bordetella pertussis Adenylate Cyclase Toxin, a Member of the RTX Toxin Family C Martín, MA Requero, J Masin, I Konopasek, FM Goni, P Sebo, ... Journal of bacteriology 186 (12), 3760-3765, 2004 | 102 | 2004 |
Reversible adsorption and nonreversible insertion of Escherichia coli alpha-hemolysin into lipid bilayers L Bakás, H Ostolaza, WL Vaz, FM Goñi Biophysical journal 71 (4), 1869-1876, 1996 | 102 | 1996 |
The p.Leu167del Mutation in APOE Gene Causes Autosomal Dominant Hypercholesterolemia by Down-regulation of LDL Receptor Expression in Hepatocytes A Cenarro, A Etxebarria, I de Castro-Orós, M Stef, AM Bea, L Palacios, ... The Journal of Clinical Endocrinology & Metabolism 101 (5), 2113-2121, 2016 | 95 | 2016 |
Insertion of Escherichia coliα‐haemolysin in lipid bilayers as a non‐transmembrane integral protein: prediction and experiment A Soloaga, MP Veiga, LM García‐Segura, H Ostolaza, R Brasseur, ... Molecular microbiology 31 (4), 1013-1024, 1999 | 90 | 1999 |
The Binding of Divalent Cations to Escherichia coliα‐Haemolysin H Ostolaza, A Soloaga, FM Goñi European journal of biochemistry 228 (1), 39-44, 1995 | 84 | 1995 |
Permeabilizing action of an antimicrobial lactoferricin‐derived peptide on bacterial and artificial membranes O Aguilera, H Ostolaza, LM Quiros, JF Fierro FEBS letters 462 (3), 273-277, 1999 | 80 | 1999 |
The calcium-binding C-terminal domain of Escherichia coli α-hemolysin is a major determinant in the surface-active properties of the protein L Sánchez-Magraner, AR Viguera, M Garcia-Pacios, MP Garcillán, ... Journal of biological chemistry 282 (16), 11827-11835, 2007 | 74 | 2007 |
Interaction of the bacterial protein toxin α-haemolysin with model membranes: Protein binding does not always lead to lytic activity H Ostolaza FEBS letters 371 (3), 303-306, 1995 | 72 | 1995 |
Calcium-dependent conformation of E. coli α-haemolysin. Implications for the mechanism of membrane insertion and lysis L Bakás, MP Veiga, A Soloaga, H Ostolaza, FM Goñi Biochimica et Biophysica Acta (BBA)-Biomembranes 1368 (2), 225-234, 1998 | 71 | 1998 |
A receptor-binding region in Escherichia coli α-haemolysin AL Cortajarena, FM Goni, H Ostolaza Journal of Biological Chemistry 278 (21), 19159-19163, 2003 | 70 | 2003 |
α-Haemolysin from E. coli purification and self-aggregation properties H Ostolaza, B Bartolomé, JL Serra, F de la Cruz, FM Goñi FEBS letters 280 (2), 195-198, 1991 | 65 | 1991 |
Validation of LDLr activity as a tool to improve genetic diagnosis of familial hypercholesterolemia: a retrospective on functional characterization of LDLr variants A Benito-Vicente, KB Uribe, S Jebari, U Galicia-Garcia, H Ostolaza, ... International journal of molecular sciences 19 (6), 1676, 2018 | 60 | 2018 |
Functional Characterization and Classification of Frequent Low‐Density Lipoprotein Receptor Variants A Etxebarria, A Benito‐Vicente, L Palacios, M Stef, A Cenarro, F Civeira, ... Human Mutation 36 (1), 129-141, 2015 | 56 | 2015 |
Functional characterization of splicing and ligand‐binding domain variants in the LDL receptor A Etxebarria, L Palacios, M Stef, D Tejedor, KB Uribe, A Oleaga, ... Human mutation 33 (1), 232-243, 2012 | 52 | 2012 |