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Grace Q. Gong
Grace Q. Gong
Investigator Scientist
Verified email at mrc-lmb.cam.ac.uk
Title
Cited by
Cited by
Year
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention
R Basnet, GQ Gong, C Li, MW Wang
Acta Pharmaceutica Sinica B 8 (5), 767-771, 2018
372018
A small-molecule PI3Kα activator for cardioprotection and neuroregeneration
GQ Gong, B Bilanges, B Allsop, GR Masson, V Roberton, T Askwith, ...
Nature 618 (7963), 159-168, 2023
252023
A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion
SD Heitz, DJ Hamelin, RM Hoffmann, N Greenberg, G Salloum, Z Erami, ...
Journal of Biological Chemistry 294 (12), 4621-4633, 2019
132019
Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds
GQ Gong, K Wang, XC Dai, Y Zhou, R Basnet, Y Chen, DH Yang, WJ Lee, ...
Acta Pharmacologica Sinica 39 (12), 1902-1912, 2018
132018
High-throughput screening campaigns against a PI3Kα isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds
J Wang, GQ Gong, Y Zhou, WJ Lee, CM Buchanan, WA Denny, ...
Acta Pharmacologica Sinica 39 (11), 1816-1822, 2018
122018
Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists
L Lin, G Lin, Q Zhou, RAD Bathgate, GQ Gong, D Yang, Q Liu, MW Wang
Bioorganic Chemistry 110, 104782, 2021
82021
Combining properties of different classes of PI3Kα inhibitors to understand the molecular features that confer selectivity
GQ Gong, JD Kendall, JMJ Dickson, GW Rewcastle, CM Buchanan, ...
Biochemical Journal 474 (13), 2261-2276, 2017
72017
Precision Targeting of Mutant PI3Kα
GQ Gong, B Vanhaesebroeck
Cancer Discovery 14 (2), 204-207, 2024
2024
Designing Compounds that Probe the Phosphatidylinositol 3-Kinase Signalosome
GQ Gong
PhD Thesis-University of Auckland, 2017
2017
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Articles 1–9