| Generation and Characterization of a Cyp2f2-null Mouse and Studies on the Role of CYP2F2 in Naphthalene-induced Toxicity in the Lung and Nasal Olfactory Mucosa L Li, Y Wei, L Van Winkle, QY Zhang, X Zhou, J Hu, F Xie, K Kluetzman, ... Journal of Pharmacology and Experimental Therapeutics 339 (1), 62-71, 2011 | 85 | 2011 |
| Identification of cytochrome P450 oxidoreductase gene variants that are significantly associated with the interindividual variations in warfarin maintenance dose X Zhang, L Li, X Ding, LS Kaminsky Drug Metabolism and Disposition 39 (8), 1433-1439, 2011 | 62 | 2011 |
| Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse model Y Wei, H Wu, L Li, Z Liu, X Zhou, QY Zhang, Y Weng, J D'Agostino, G Ling, ... Drug Metabolism and Disposition 40 (6), 1144-1150, 2012 | 38 | 2012 |
| Generation and Characterization of a Novel Cyp2a (4/5) bgs-null Mouse Model Y Wei, L Li, X Zhou, QY Zhang, A Dunbar, F Liu, K Kluetzman, W Yang, ... Drug Metabolism and Disposition, 2012 | 34 | 2012 |
| Human CYP2A13 and CYP2F1 mediate naphthalene toxicity in the lung and nasal mucosa of CYP2A13/2F1-humanized mice L Li, S Carratt, M Hartog, N Kovalchuk, K Jia, Y Wang, QY Zhang, ... Environmental health perspectives 125 (6), 067004, 2017 | 33 | 2017 |
| Identification of cytochrome P450 enzymes critical for lung tumorigenesis by the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): insights from … L Li, V Megaraj, Y Wei, X Ding Carcinogenesis 35 (11), 2584-2591, 2014 | 31 | 2014 |
| Dynamic, multimodal hydrogel actuators using porphyrin-based visible light photoredox catalysis in a thermoresponsive polymer network F Amir, X Li, MC Gruschka, ND Colley, L Li, R Li, HR Linder, SA Sell, ... Chemical Science 11 (40), 10910-10920, 2020 | 26 | 2020 |
| Impact of nicotine metabolism on nicotine’s pharmacological effects and behavioral responses: insights from a Cyp2a (4/5) bgs-null mouse L Li, K Jia, X Zhou, SE McCallum, LB Hough, X Ding Journal of Pharmacology and Experimental Therapeutics 347 (3), 746-754, 2013 | 23 | 2013 |
| Essential role of the cytochrome P450 enzyme CYP2A5 in olfactory mucosal toxicity of naphthalene J Hu, L Sheng, L Li, X Zhou, F Xie, J D’Agostino, Y Li, X Ding Drug metabolism and disposition 42 (1), 23-27, 2014 | 22 | 2014 |
| Respective roles of CYP2A5 and CYP2F2 in the Bioactivation of 3-Methylindole in Mouse Olfactory Mucosa and Lung: Studies Using Cyp2a5-null and Cyp2f2-null Mouse Models X Zhou, J D'Agostino, L Li, CD Moore, GS Yost, X Ding Drug Metabolism and Disposition, 2012 | 20 | 2012 |
| Generation of a mouse model with a reversible hypomorphic cytochrome P450 reductase gene: utility for tissue-specific rescue of the reductase expression, and insights from a … Y Wei, X Zhou, C Fang, L Li, K Kluetzman, W Yang, QY Zhang, X Ding Journal of Pharmacology and Experimental Therapeutics 334 (1), 69-77, 2010 | 19 | 2010 |
| Metabolism of styrene to styrene oxide and vinylphenols in cytochrome P450 2F2-and P450 2E1-knockout mouse liver and lung microsomes S Shen, L Li, X Ding, J Zheng Chemical research in toxicology 27 (1), 27-33, 2014 | 18 | 2014 |
| Role of CYP2B in phenobarbital-induced hepatocyte proliferation in mice L Li, X Bao, QY Zhang, M Negishi, X Ding Drug Metabolism and Disposition 45 (8), 977-981, 2017 | 16 | 2017 |
| Impact of hepatic P450-mediated biotransformation on the disposition and respiratory tract toxicity of inhaled naphthalene N Kovalchuk, J Kelty, L Li, M Hartog, QY Zhang, P Edwards, L Van Winkle, Ding X Toxicol Appl Pharmacol 329 (18), 1-8, 2017 | 16 | 2017 |
| Characterization of CYP2B6 in a CYP2B6-humanized mouse model: inducibility in the liver by phenobarbital and dexamethasone and role in nicotine metabolism in vivo Z Liu, L Li, H Wu, J Hu, J Ma, QY Zhang, X Ding Drug Metabolism and Disposition 43 (2), 208-216, 2015 | 16 | 2015 |
| Generation and characterization of a novel CYP2A13-transgenic mouse model K Jia, L Li, Z Liu, M Hartog, K Kluetzman, QY Zhang, X Ding Drug Metabolism and Disposition 42 (8), 1341-1348, 2014 | 16 | 2014 |
| Proximal tubular vacuolization and hypersensitivity to drug-induced nephrotoxicity in male mice with decreased expression of the NADPH-cytochrome P450 reductase L Ding, L Li, S Liu, X Bao, KG Dickman, SS Sell, C Mei, QY Zhang, J Gu, ... Toxicological Sciences 173 (2), 362-372, 2020 | 14 | 2020 |
| A CYP2B6-humanized mouse model and its potential applications L Li, QY Zhang, X Ding Drug metabolism and pharmacokinetics 33 (1), 2-8, 2018 | 7 | 2018 |
| Biochemical function of the respiratory tract: metabolism of xenobiotics X Ding, L Li, LS Van Winkle, QY Zhang Elsevier, 2018 | 5 | 2018 |
| Role of human CYP2A13 and CYP2F1 in naphthalene bioactivation and toxicity in the lung and nasal mucosa of a CYP2A13/2F1‐humanized Mouse (LB636) L Li, K Jia, M Hartog, Y Wang, L Van Winkle, X Ding The FASEB Journal 28, LB636, 2014 | 1 | 2014 |
