| Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease PK Luukkonen, S Dufour, K Lyu, XM Zhang, A Hakkarainen, TE Lehtimäki, ... Proceedings of the National Academy of Sciences 117 (13), 7347-7354, 2020 | 194 | 2020 |
| A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance K Lyu, Y Zhang, D Zhang, M Kahn, KW Ter Horst, MRS Rodrigues, ... Cell metabolism 32 (4), 654-664. e5, 2020 | 101 | 2020 |
| Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents DF Vatner, L Goedeke, JPG Camporez, K Lyu, AR Nasiri, D Zhang, ... Diabetologia 61, 1435-1446, 2018 | 62 | 2018 |
| Anti‐inflammatory effects of oestrogen mediate the sexual dimorphic response to lipid‐induced insulin resistance JP Camporez, K Lyu, EL Goldberg, D Zhang, GW Cline, MJ Jurczak, ... The Journal of physiology 597 (15), 3885-3903, 2019 | 58 | 2019 |
| Leptin mediates postprandial increases in body temperature through hypothalamus–adrenal medulla–adipose tissue crosstalk RJ Perry, K Lyu, J Dong, X Li, Y Yang, H Qing, A Wang, X Yang, ... The Journal of clinical investigation 130 (4), 2001-2016, 2020 | 33 | 2020 |
| Short-term overnutrition induces white adipose tissue insulin resistance through sn-1, 2-diacylglycerol/PKCε/insulin receptor Thr1160 phosphorylation K Lyu, D Zhang, J Song, X Li, RJ Perry, VT Samuel, GI Shulman JCI insight 6 (4), 2021 | 31 | 2021 |
| Membrane-bound sn-1, 2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice A Abulizi, DF Vatner, Z Ye, Y Wang, JP Camporez, D Zhang, M Kahn, ... Journal of Lipid Research 61 (12), 1565-1576, 2020 | 16 | 2020 |
| Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice RC Gaspar, K Lyu, BT Hubbard, BP Leitner, PK Luukkonen, SM Hirabara, ... Diabetologia 66 (3), 567-578, 2023 | 3 | 2023 |
| Membrane sn-1, 2 diacylglycerol mediates lipid-induced hepatic insulin resistance in vivo K Lyu, D Zhang, Y Nozaki, Y Zhang, S Bhanot, G Cline, V Samuel, ... Diabetes 67 (Supplement_1), 2018 | 3 | 2018 |
| Membrane bound diacylglycerols explain the dissociation of hepatic insulin resistance from steatosis in MTTP−/− mice A Abulizi, DF Vatner, Z Ye, Y Wang, JP Camporez, D Zhang J. Lipid Res., 2020 | 2 | 2020 |
| 501-P: Lower Plasma Membrane Sn-1, 2-Diacylglycerol Content and PKCepsilon/theta Activity Explain the Athlete’s Paradox RC Gaspar, K Lyu, BT Hubbard, B Leitner, P Luukkonen, S Hirabara, ... Diabetes 70 (Supplement_1), 2021 | | 2021 |
| Diacylglycerol-PKC Epsilon-Insulin Receptor as a Key Regulatory Axis of Hepatic and White Adipose Tissue Insulin Signaling K Lyu Yale University, 2021 | | 2021 |
| Carbohydrate restriction reverses NAFLD by altering hepatic mitochondrial fluxes in humans P Luukkonen, S Dufour, K Lyu, XM Zhang, A Hakkarainen, TE Lehtimäki, ... Journal of Hepatology 73, S14, 2020 | | 2020 |
| 205-OR: Hepatic Protein Kinase Ce Is Necessary and Sufficient in Mediating Lipid-Induced Hepatic Insulin Resistance K Lyu, D Zhang, M Kahn, MRS Rodrigues, S Hirabara, P Luukkonen, ... Diabetes 69 (Supplement_1), 2020 | | 2020 |
| 99-OR: Leptin Mediates Postprandial Thermogenesis through a Hypothalamic-Adrenomedullary-BAT Axis RJ Perry, J DONG, KUN LYU, X LI, GI SHULMAN Diabetes 68 (Supplement_1), 2019 | | 2019 |
| 266-OR: Plasma Membrane sn-1, 2 Diacylglycerol Mediates Lipid-Induced Hepatic Insulin Resistance K Lyu, Y Zhang, D Zhang, M Kahn, Y Nozaki, S Bhanot, J Bogan, G Cline, ... Diabetes 68 (Supplement_1), 2019 | | 2019 |
| 1782-P: Mechanism of Lipid-Induced White Adipose Tissue Insulin Resistance Y Zhang, D Zhang, K Lyu, JD Song, X Li, RJ Perry, V Samuel, GI Shulman Diabetes 68 (Supplement_1), 2019 | | 2019 |
