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Emma Titmuss
Emma Titmuss
Canada's Michael Smith Genome Sciences Centre
Verified email at bcgsc.ca
Title
Cited by
Cited by
Year
Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes
E Pleasance, E Titmuss, L Williamson, H Kwan, L Culibrk, EY Zhao, ...
Nature Cancer 1 (4), 452-468, 2020
1232020
Identification and analyses of extra-cranial and cranial rhabdoid tumor molecular subgroups reveal tumors with cytotoxic T cell infiltration
HJE Chun, PD Johann, K Milne, M Zapatka, A Buellesbach, N Ishaque, ...
Cell reports 29 (8), 2338-2354. e7, 2019
832019
Genome and transcriptome biomarkers of response to immune checkpoint inhibitors in advanced solid tumors
A Pender, E Titmuss, ED Pleasance, KY Fan, H Pearson, SD Brown, ...
Clinical Cancer Research 27 (1), 202-212, 2021
622021
Whole-genome and transcriptome analysis enhances precision cancer treatment options
E Pleasance, A Bohm, LM Williamson, JMT Nelson, Y Shen, M Bonakdar, ...
Annals of Oncology 33 (9), 939-949, 2022
592022
Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade–specific epigenome and transcriptome landscapes
A Gagliardi, VL Porter, Z Zong, R Bowlby, E Titmuss, C Namirembe, ...
Nature genetics 52 (8), 800-810, 2020
482020
Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury
LM Williamson, CM Rive, D Di Francesco, E Titmuss, HJE Chun, ...
NPJ Precision Oncology 5 (1), 103, 2021
242021
Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma
JT Topham, ES Tsang, JM Karasinska, A Metcalfe, H Ali, SE Kalloger, ...
Nature Communications 13 (1), 5941, 2022
152022
Clinical and cost outcomes following genomics‐informed treatment for advanced cancers
D Weymann, S Pollard, B Chan, E Titmuss, A Bohm, J Laskin, SJM Jones, ...
Cancer Medicine 10 (15), 5131-5140, 2021
142021
Therapeutic implication of genomic landscape of adult metastatic sarcoma
X Feng, E Pleasance, EY Zhao, T Ng, JK Grewal, N Mohammad, ...
JCO precision oncology 3, 1-25, 2019
142019
Endogenous retrovirus transcript levels are associated with immunogenic signatures in multiple metastatic cancer types
JT Topham, E Titmuss, ED Pleasance, LM Williamson, JM Karasinska, ...
Molecular cancer therapeutics 19 (9), 1889-1897, 2020
122020
Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy
Y Zhang, F Chen, E Pleasance, L Williamson, CJ Grisdale, E Titmuss, ...
Cell reports 37 (7), 2021
92021
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration
ES Tsang, V Csizmok, LM Williamson, E Pleasance, JT Topham, ...
NPJ Precision Oncology 7 (1), 31, 2023
62023
Establishing a framework for the clinical translation of germline findings in precision oncology
K Dixon, S Young, Y Shen, ML Thibodeau, A Fok, E Pleasance, E Zhao, ...
JNCI Cancer Spectrum 4 (5), pkaa045, 2020
62020
TMBur: a distributable tumor mutation burden approach for whole genome sequencing
E Titmuss, RD Corbett, S Davidson, S Abbasi, LM Williamson, ...
BMC Medical Genomics 15 (1), 190, 2022
52022
Liver Metastases and Immune Checkpoint Inhibitor Efficacy in Patients with Refractory Metastatic Colorectal Cancer: A Secondary Analysis of a Randomized Clinical Trial
EX Chen, JM Loree, E Titmuss, DJ Jonker, HF Kennecke, S Berry, ...
JAMA Network Open 6 (12), e2346094-e2346094, 2023
42023
Comprehensive transcriptome analysis reveals link between epigenetic dysregulation, endogenous retrovirus expression and immunogenicity in metastatic colorectal carcinoma.
SR Mendis, JT Topham, E Titmuss, L Williamson, ED Pleasance, ...
Journal of Clinical Oncology 37 (15_suppl), 3535-3535, 2019
42019
Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers
JM Romero, E Titmuss, Y Wang, J Vafiadis, A Pacis, GH Jang, A Zhang, ...
NPJ Precision Oncology 7 (1), 73, 2023
32023
Exceptional response to combination ipilimumab and nivolumab in metastatic uveal melanoma: Insights from genomic analysis
SY Irene, K Wee, L Williamson, E Titmuss, J An, S Naderi-Azad, C Metcalf, ...
Melanoma research 32 (4), 278-285, 2022
22022
Immune activation following Irbesartan treatment in a colorectal cancer patient: a case study
E Titmuss, K Milne, MR Jones, T Ng, JT Topham, SD Brown, DF Schaeffer, ...
International Journal of Molecular Sciences 24 (6), 5869, 2023
12023
Assessment of a 4-chemokine signature in prediction of T-cell inflammation and response to immune checkpoint inhibition across tumor types.
JM Romero, E Titmuss, Y Wang, J Vafiadis, A Pacis, GH Jang, A Zhang, ...
Journal of Clinical Oncology 40 (16_suppl), 2558-2558, 2022
12022
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