| Combined MEK and STAT3 inhibition uncovers stromal plasticity by enriching for cancer-associated fibroblasts with mesenchymal stem cell-like features to overcome immunotherapy … J Datta, X Dai, A Bianchi, IDC Silva, S Mehra, VT Garrido, P Lamichhane, ... Gastroenterology 163 (6), 1593-1612, 2022 | 54 | 2022 |
| Targeting tumor–stromal IL6/STAT3 signaling through IL1 receptor inhibition in pancreatic Cancer AR Dosch, S Singh, X Dai, S Mehra, IDC Silva, A Bianchi, S Srinivasan, ... Molecular cancer therapeutics 20 (11), 2280-2290, 2021 | 28 | 2021 |
| Cell-autonomous Cxcl1 sustains tolerogenic circuitries and stromal inflammation via neutrophil-derived TNF in pancreatic cancer A Bianchi, I De Castro Silva, NU Deshpande, S Singh, S Mehra, ... Cancer discovery 13 (6), 1428-1453, 2023 | 24 | 2023 |
| Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer J Datta, A Bianchi, I De Castro Silva, NU Deshpande, LL Cao, S Mehra, ... Oncogene 41 (28), 3640-3654, 2022 | 18 | 2022 |
| Urolithin A attenuates severity of chronic pancreatitis associated with continued alcohol intake by inhibiting PI3K/AKT/mTOR signaling S Mehra, S Srinivasan, S Singh, Z Zhou, V Garrido, IDC Silva, TM Totiger, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 323 (4 …, 2022 | 10 | 2022 |
| Overcoming acquired drug resistance to cancer therapies through targeted STAT3 inhibition S Singh, HJ Gomez, S Thakkar, SP Singh, AS Parihar International Journal of Molecular Sciences 24 (5), 4722, 2023 | 9 | 2023 |
| A broad-based characterization of a cell-penetrating, single domain camelid bi-specific antibody monomer that targets STAT3 and KRAS dependent cancers S Singh, G Murillo, J Richner, SP Singh, E Berleth, V Kumar, R Mehta, ... International Journal of Molecular Sciences 23 (14), 7565, 2022 | 5 | 2022 |
| Interleukin-1 signaling in solid organ malignancies AR Dosch, S Singh, NS Nagathihalli, J Datta, NB Merchant Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1877 (1), 188670, 2022 | 5 | 2022 |
| A Novel Model for NSAID Induced Gastroenteropathy and the Proposed Role of TNF-α: Way Forward for the Discovery of Futuristic Therapeutic Interventions SP Singh, M Nivsarkar 2016 3rd Nirma Institute of Pharmacy International Conference-NIPiCON, 2016 | 5 | 2016 |
| Emerging Role of CREB in Epithelial to Mesenchymal Plasticity of Pancreatic Cancer S Mehra, S Singh, N Nagathihalli Frontiers in oncology 12, 925687, 2022 | 4 | 2022 |
| Pancreatic pseudocyst of the kidney: computed tomographic diagnosis. SP Singh, S Vashisht, R Sharma, S Mukhopadhyay, M Berry Tropical Gastroenterology: Official Journal of the Digestive Diseases …, 1993 | 3 | 1993 |
| Remodeling of stromal immune microenvironment by urolithin A improves survival with immune checkpoint blockade in pancreatic cancer S Mehra, VT Garrido, AR Dosch, P Lamichhane, S Srinivasan, SP Singh, ... Cancer research communications 3 (7), 1224-1236, 2023 | 2 | 2023 |
| Tumor Cell–Intrinsic p38 MAPK Signaling Promotes IL1α-Mediated Stromal Inflammation and Therapeutic Resistance in Pancreatic Cancer SP Singh, AR Dosch, S Mehra, I De Castro Silva, A Bianchi, VT Garrido, ... Cancer Research 84 (8), 1320-1332, 2024 | 1 | 2024 |
| Protective Effects of Urolithin A on Alcoholic Chronic Pancreatitis via Inhibiting PI3K/AKT/mTOR Signaling Pathway S Mehra, S Srinivasan, X Dai, A Dosch, S Singh, A Bianchi, I Silva, ... Pancreas 50 (7), 1082-1082, 2021 | 1 | 2021 |
| Effect of KRAS and P-STAT3 inhibition by SBT-100 on gemcitabine and pancreatic cancer growth in vivo. S Singh, G Murillo, A Singh, S Singh, MS Parihar, AH Singh, R Mehta, ... Journal of Clinical Oncology 35 (15_suppl), e15727-e15727, 2017 | 1 | 2017 |
| Su1179 MICROBIAL METABOLITE UROLITHIN A REDUCES INFLAMMATION AND ENHANCES GUT BARRIER FUNCTION IN KRASG12D INHIBITOR MRTX1133-TREATED MOUSE MODELS OF PANCREATIC CANCER V Krishnamoorthy, S Mehra, S Jinka, H Amirian, EW Box, S Singh, ... Gastroenterology 166 (5), S-686, 2024 | | 2024 |
| Targeting p38 MAPK Signaling to Suppress Inflammatory Tumor-Stroma-Immune Crosstalk in Pancreatic Cancer SP Singh University of Miami, 2024 | | 2024 |
| CREB-ROCK driven extracellular matrix remodeling exasperates pancreatic cancer progression S Jinka, S Mehra, V Krishnamoorthy, A Bianchi, K Rajkumar, A Adams, ... Cancer Research 84 (6_Supplement), 4277-4277, 2024 | | 2024 |
| JNK inhibition reprograms the tumor-immune-microenvironment to overcome chemoresistance in PDAC EW Box III, S Singh, VT Garrido, S Mehra, H Amirian, EM Dickey, ... ANNALS OF SURGICAL ONCOLOGY 31 (1), S61-S62, 2024 | | 2024 |
| A novel mechanism of immunotherapy sensitivity following platinum chemotherapy resistance in pancreatic cancer patients with germline homologous recombination deficiency I Ogobuiro, K Rajkumar, A Bianchi, L Caeiro, H Amirian, L Nivelo, ... ANNALS OF SURGICAL ONCOLOGY 31 (1), S24-S25, 2024 | | 2024 |
