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Iman van den Bout
Iman van den Bout
Verified email at up.ac.za
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Cited by
Year
Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin
K Wilhelmsen, SHM Litjens, I Kuikman, N Tshimbalanga, H Janssen, ...
The Journal of cell biology 171 (5), 799-810, 2005
5642005
PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions
I Van den Bout, N Divecha
Journal of cell science 122 (21), 3837-3850, 2009
3632009
Integrin αvβ3 controls activity and oncogenic potential of primed c-Src
S Huveneers, I van den Bout, P Sonneveld, A Sancho, A Sonnenberg, ...
Cancer research 67 (6), 2693-2700, 2007
772007
Epigenetic regulation of galectin-3 expression by β1 integrins promotes cell adhesion and migration
C Margadant, I van den Bout, AL van Boxtel, VL Thijssen, A Sonnenberg
Journal of Biological Chemistry 287 (53), 44684-44693, 2012
642012
Rac controls PIP5K localisation and PtdIns(4,5)P2 synthesis, which modulates vinculin localisation and neurite dynamics
JR Halstead, NE Savaskan, I Van Den Bout, F Van Horck, ...
Journal of cell science 123 (20), 3535-3546, 2010
542010
Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT
K Visuttijai, J Pettersson, Y Mehrbani Azar, I van den Bout, C Örndal, ...
PLoS One 11 (10), e0164063, 2016
312016
Reciprocal integrin/integrin antagonism through kindlin-2 and Rho GTPases regulates cell cohesion and collective migration
I Van der Bijl, K Nawaz, U Kazlauskaite, AM Van Stalborch, S Tol, ...
Matrix Biology 93, 60-78, 2020
212020
A bis-sulphamoylated estradiol derivative induces ROS-dependent cell cycle abnormalities and subsequent apoptosis
MH Visagie, I van den Bout, AM Joubert
PLoS One 12 (4), e0176006, 2017
212017
Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization
RJ van Vuuren, M Botes, T Jurgens, AM Joubert, I van den Bout
Cancer cell international 19, 1-10, 2019
172019
Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations
A Theron, R Prudent, E Nolte, I van den Bout, R Punchoo, S Marais, ...
Cancer chemotherapy and pharmacology 75, 431-437, 2015
172015
Collaboration of AMPK and PKC to induce phosphorylation of Ser413 on PIP5K1B resulting in decreased kinase activity and reduced PtdIns(4,5)P2 synthesis in …
I Van den Bout, DR Jones, ZH Shah, JR Halstead, WJ Keune, ...
Biochemical Journal 455 (3), 347-358, 2013
132013
A novel non-sulphamoylated 2-methoxyestradiol derivative causes detachment of breast cancer cells by rapid disassembly of focal adhesions
M Botes, T Jurgens, Z Riahi, M Visagie, R Janse van Vuuren, AM Joubert, ...
Cancer Cell International 18, 1-12, 2018
92018
Investigation into the mechanism regulating MRP localization
I van den Bout, J van Rheenen, AA van Angelen, J de Rooij, ...
Experimental cell research 314 (2), 330-341, 2008
82008
Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture
AA Ellero, I Van den Bout, M Vlok, AD Cromarty, T Hurrell
Scientific Reports 11 (1), 10917, 2021
62021
The regulation of MacMARCKS expression by integrin β3
I van den Bout, HH Truong, S Huveneers, I Kuikman, EHJ Danen, ...
Experimental cell research 313 (6), 1260-1269, 2007
62007
Comparative evaluation of the cytotoxicity of Doxorubicin in BT-20 triple-negative breast carcinoma monolayer and spheroid cultures
KN Ncube, T Jurgens, V Steenkamp, AD Cromarty, I van den Bout, ...
Biomedicines 11 (5), 1484, 2023
32023
How nuclear envelope dynamics can direct laminopathy phenotypes
D van Heerden, S Klima, I van den Bout
Current Opinion in Cell Biology 86, 102290, 2024
22024
Considerations for enhanced mesenchymal stromal/stem cell myogenic commitment in vitro
S Grobbelaar, AE Mercier, I Van den Bout, C Durandt, MS Pepper
Clinical and Translational Science 17 (1), e13703, 2024
12024
Comparison of the effects of electronic cigarette vapours and tobacco smoke extracts on human neutrophils in vitro
GA Richards, AJ Theron, I Van den Bout, R Anderson, C Feldman, ...
ERJ Open Research 9 (3), 2023
12023
Functional rescue of inactivating mutations of the human neurokinin 3 receptor using pharmacological chaperones
RC Anderson, S Hanyroup, YB Song, Z Mohamed-Moosa, I Van den Bout, ...
International Journal of Molecular Sciences 23 (9), 4587, 2022
12022
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Articles 1–20