Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin K Wilhelmsen, SHM Litjens, I Kuikman, N Tshimbalanga, H Janssen, ... The Journal of cell biology 171 (5), 799-810, 2005 | 564 | 2005 |
PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions I Van den Bout, N Divecha Journal of cell science 122 (21), 3837-3850, 2009 | 363 | 2009 |
Integrin αvβ3 controls activity and oncogenic potential of primed c-Src S Huveneers, I van den Bout, P Sonneveld, A Sancho, A Sonnenberg, ... Cancer research 67 (6), 2693-2700, 2007 | 77 | 2007 |
Epigenetic regulation of galectin-3 expression by β1 integrins promotes cell adhesion and migration C Margadant, I van den Bout, AL van Boxtel, VL Thijssen, A Sonnenberg Journal of Biological Chemistry 287 (53), 44684-44693, 2012 | 64 | 2012 |
Rac controls PIP5K localisation and PtdIns(4,5)P2 synthesis, which modulates vinculin localisation and neurite dynamics JR Halstead, NE Savaskan, I Van Den Bout, F Van Horck, ... Journal of cell science 123 (20), 3535-3546, 2010 | 54 | 2010 |
Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT K Visuttijai, J Pettersson, Y Mehrbani Azar, I van den Bout, C Örndal, ... PLoS One 11 (10), e0164063, 2016 | 31 | 2016 |
Reciprocal integrin/integrin antagonism through kindlin-2 and Rho GTPases regulates cell cohesion and collective migration I Van der Bijl, K Nawaz, U Kazlauskaite, AM Van Stalborch, S Tol, ... Matrix Biology 93, 60-78, 2020 | 21 | 2020 |
A bis-sulphamoylated estradiol derivative induces ROS-dependent cell cycle abnormalities and subsequent apoptosis MH Visagie, I van den Bout, AM Joubert PLoS One 12 (4), e0176006, 2017 | 21 | 2017 |
Novel sulphamoylated 2-methoxy estradiol derivatives inhibit breast cancer migration by disrupting microtubule turnover and organization RJ van Vuuren, M Botes, T Jurgens, AM Joubert, I van den Bout Cancer cell international 19, 1-10, 2019 | 17 | 2019 |
Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations A Theron, R Prudent, E Nolte, I van den Bout, R Punchoo, S Marais, ... Cancer chemotherapy and pharmacology 75, 431-437, 2015 | 17 | 2015 |
Collaboration of AMPK and PKC to induce phosphorylation of Ser413 on PIP5K1B resulting in decreased kinase activity and reduced PtdIns(4,5)P2 synthesis in … I Van den Bout, DR Jones, ZH Shah, JR Halstead, WJ Keune, ... Biochemical Journal 455 (3), 347-358, 2013 | 13 | 2013 |
A novel non-sulphamoylated 2-methoxyestradiol derivative causes detachment of breast cancer cells by rapid disassembly of focal adhesions M Botes, T Jurgens, Z Riahi, M Visagie, R Janse van Vuuren, AM Joubert, ... Cancer Cell International 18, 1-12, 2018 | 9 | 2018 |
Investigation into the mechanism regulating MRP localization I van den Bout, J van Rheenen, AA van Angelen, J de Rooij, ... Experimental cell research 314 (2), 330-341, 2008 | 8 | 2008 |
Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture AA Ellero, I Van den Bout, M Vlok, AD Cromarty, T Hurrell Scientific Reports 11 (1), 10917, 2021 | 6 | 2021 |
The regulation of MacMARCKS expression by integrin β3 I van den Bout, HH Truong, S Huveneers, I Kuikman, EHJ Danen, ... Experimental cell research 313 (6), 1260-1269, 2007 | 6 | 2007 |
Comparative evaluation of the cytotoxicity of Doxorubicin in BT-20 triple-negative breast carcinoma monolayer and spheroid cultures KN Ncube, T Jurgens, V Steenkamp, AD Cromarty, I van den Bout, ... Biomedicines 11 (5), 1484, 2023 | 3 | 2023 |
How nuclear envelope dynamics can direct laminopathy phenotypes D van Heerden, S Klima, I van den Bout Current Opinion in Cell Biology 86, 102290, 2024 | 2 | 2024 |
Considerations for enhanced mesenchymal stromal/stem cell myogenic commitment in vitro S Grobbelaar, AE Mercier, I Van den Bout, C Durandt, MS Pepper Clinical and Translational Science 17 (1), e13703, 2024 | 1 | 2024 |
Comparison of the effects of electronic cigarette vapours and tobacco smoke extracts on human neutrophils in vitro GA Richards, AJ Theron, I Van den Bout, R Anderson, C Feldman, ... ERJ Open Research 9 (3), 2023 | 1 | 2023 |
Functional rescue of inactivating mutations of the human neurokinin 3 receptor using pharmacological chaperones RC Anderson, S Hanyroup, YB Song, Z Mohamed-Moosa, I Van den Bout, ... International Journal of Molecular Sciences 23 (9), 4587, 2022 | 1 | 2022 |