| Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis BD Hobbs, K De Jong, M Lamontagne, Y Bossé, N Shrine, MS Artigas, ... Nature genetics 49 (3), 426-432, 2017 | 369 | 2017 |
| Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease JH Yun, A Lamb, R Chase, D Singh, MM Parker, A Saferali, J Vestbo, ... Journal of allergy and clinical immunology 141 (6), 2037-2047. e10, 2018 | 196 | 2018 |
| CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies MJ McGeachie, AC Wu, SM Tse, GL Clemmer, J Sordillo, BE Himes, ... Journal of Allergy and Clinical Immunology 136 (6), 1503-1510, 2015 | 57 | 2015 |
| RNA sequencing identifies novel non-coding RNA and exon-specific effects associated with cigarette smoking MM Parker, RP Chase, A Lamb, A Reyes, A Saferali, JH Yun, BE Himes, ... BMC medical genomics 10, 1-10, 2017 | 56 | 2017 |
| Circulating microRNAs and treatment response in childhood asthma J Li, R Panganiban, AT Kho, MJ McGeachie, L Farnam, RP Chase, ... American journal of respiratory and critical care medicine 202 (1), 65-72, 2020 | 50 | 2020 |
| RNA-sequencing across three matched tissues reveals shared and tissue-specific gene expression and pathway signatures of COPD JD Morrow, RP Chase, MM Parker, K Glass, M Seo, M Divo, CA Owen, ... Respiratory research 20, 1-12, 2019 | 50 | 2019 |
| CRISPLD2 (LGL1) inhibits proinflammatory mediators in human fetal, adult, and COPD lung fibroblasts and epithelial cells H Zhang, AT Kho, Q Wu, AJ Halayko, K Limbert Rempel, RP Chase, ... Physiological Reports 4 (17), e12942, 2016 | 33 | 2016 |
| Identification of an emphysema-associated genetic variant near TGFB2 with regulatory effects in lung fibroblasts MM Parker, Y Hao, F Guo, B Pham, R Chase, J Platig, MH Cho, CP Hersh, ... Elife 8, e42720, 2019 | 28 | 2019 |
| COMPSRA: a COMprehensive platform for small RNA-Seq data analysis J Li, AT Kho, RP Chase, L Pantano, L Farnam, SS Amr, KG Tantisira Scientific Reports 10 (1), 4552, 2020 | 27 | 2020 |
| Analysis of genetically driven alternative splicing identifies FBXO38 as a novel COPD susceptibility gene A Saferali, JH Yun, MM Parker, P Sakornsakolpat, RP Chase, A Lamb, ... PLoS genetics 15 (7), e1008229, 2019 | 24 | 2019 |
| Genomics and response to long-term oxygen therapy in chronic obstructive pulmonary disease M Seo, W Qiu, W Bailey, GJ Criner, MT Dransfield, AL Fuhlbrigge, ... Journal of Molecular Medicine 96, 1375-1385, 2018 | 21 | 2018 |
| Genomic signatures of the unjamming transition in compressed human bronchial epithelial cells M De Marzio, A Kılıç, E Maiorino, JA Mitchel, C Mwase, MJ O’Sullivan, ... Science Advances 7 (30), eabf1088, 2021 | 20 | 2021 |
| Integrative Genomics Analysis Identifies ACVR1B as a Candidate Causal Gene of Emphysema Distribution A Boueiz, B Pham, R Chase, A Lamb, S Lee, ZZC Naing, MH Cho, ... American journal of respiratory cell and molecular biology 60 (4), 388-398, 2019 | 19 | 2019 |
| Biobanking and cryopreservation of human lung explants for omic analysis SG Chu, SP De Frias, Y Sakairi, RS Kelly, R Chase, K Konishi, A Blau, ... European Respiratory Journal 55 (1), 2020 | 13 | 2020 |
| Early changes in immune cell count, metabolism, and function following sleeve gastrectomy: a prospective human study T Lo, RS Haridas, EJM Rudge, RP Chase, K Heshmati, EM Lucey, ... The Journal of Clinical Endocrinology & Metabolism 107 (2), e619-e630, 2022 | 12 | 2022 |
| Investigators CO, Investigators E, LifeLines I, Group SR, International CGNI, Investigators UKB, International CGC. Genetic loci associated with chronic obstructive pulmonary … BD Hobbs, K de Jong, M Lamontagne, Y Bosse, N Shrine, MS Artigas, ... Nat Genet 49 (3), 426-32, 2017 | 12 | 2017 |
| Lung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis AJ Ghosh, BD Hobbs, JH Yun, A Saferali, M Moll, Z Xu, RP Chase, ... Respiratory research 23 (1), 97, 2022 | 11 | 2022 |
| An interferon-inducible signature of airway disease from blood gene expression profiling JH Yun, S Lee, P Srinivasa, J Morrow, R Chase, A Saferali, Z Xu, M Cho, ... European Respiratory Journal 59 (5), 2022 | 10 | 2022 |
| Commercially available blocking oligonucleotides effectively suppress unwanted hemolysis-related miRNAs in a large whole-blood RNA cohort J LaBelle, M Bowser, A Brown, L Farnam, A Kho, J Li, M McGeachie, ... The Journal of Molecular Diagnostics 23 (6), 671-682, 2021 | 10 | 2021 |
| Blood RNA sequencing shows overlapping gene expression across COPD phenotype domains AJ Ghosh, A Saferali, S Lee, R Chase, M Moll, J Morrow, J Yun, ... Thorax 77 (2), 115-122, 2022 | 8 | 2022 |
Craig HershBrigham and Women's HospitalVerified email at channing.harvard.edu
