Loss-of-function mutations in APPL1 in familial diabetes mellitus S Prudente, P Jungtrakoon, A Marucci, O Ludovico, P Buranasupkajorn, ... The American Journal of Human Genetics 97 (1), 177-185, 2015 | 180 | 2015 |
Human duct cells contribute to β cell compensation in insulin resistance E Dirice, DF De Jesus, S Kahraman, G Basile, RWS Ng, A El Ouaamari, ... JCI insight 4 (8), 2019 | 49 | 2019 |
Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes E Dirice, S Kahraman, DF De Jesus, A El Ouaamari, G Basile, RL Baker, ... Nature metabolism 1 (5), 509-518, 2019 | 43 | 2019 |
Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice DF De Jesus, K Orime, D Kaminska, T Kimura, G Basile, CH Wang, ... The Journal of clinical investigation 130 (5), 2391-2407, 2020 | 42 | 2020 |
How, when, and where do human β-cells regenerate? G Basile, RN Kulkarni, NG Morgan Current diabetes reports 19, 1-12, 2019 | 40 | 2019 |
Luseogliflozin increases beta cell proliferation through humoral factors that activate an insulin receptor-and IGF-1 receptor-independent pathway J Shirakawa, K Tajima, T Okuyama, M Kyohara, Y Togashi, DF De Jesus, ... Diabetologia 63, 577-587, 2020 | 29 | 2020 |
Abnormal exocrine–endocrine cell cross-talk promotes β-cell dysfunction and loss in MODY8 S Kahraman, E Dirice, G Basile, D Diegisser, J Alam, BB Johansson, ... Nature Metabolism 4 (1), 76-89, 2022 | 27 | 2022 |
Emerging diabetes therapies: Bringing back the β-cells G Basile, MMF Qadir, F Mauvais-Jarvis, A Vetere, V Shoba, AE Modell, ... Molecular Metabolism 60, 101477, 2022 | 22 | 2022 |
Using single-nucleus RNA-sequencing to interrogate transcriptomic profiles of archived human pancreatic islets G Basile, S Kahraman, E Dirice, H Pan, JM Dreyfuss, RN Kulkarni Genome medicine 13 (1), 128, 2021 | 22 | 2021 |
Identification and clinical characterization of adult patients with multigenerational diabetes mellitus O Ludovico, M Carella, L Bisceglia, G Basile, S Mastroianno, A Palena, ... PLoS One 10 (8), e0135855, 2015 | 18 | 2015 |
E2F1 transcription factor mediates a link between fat and islets to promote β cell proliferation in response to acute insulin resistance J Shirakawa, Y Togashi, G Basile, T Okuyama, R Inoue, M Fernandez, ... Cell reports 41 (1), 2022 | 15 | 2022 |
Infrequent TRIB3 coding variants and coronary artery disease in type 2 diabetes S Prudente, D Bailetti, C Mendonca, GC Mannino, A Fontana, F Andreozzi, ... Atherosclerosis 242 (1), 334-339, 2015 | 12 | 2015 |
Forkhead box protein O1 (FoxO1) regulates hepatic serine protease inhibitor B1 (serpinB1) expression in a non-cell-autonomous fashion A El Ouaamari, O InSug, J Shirakawa, G Basile, W Zhang, S Roger, ... Journal of Biological Chemistry 294 (3), 1059-1069, 2019 | 11 | 2019 |
Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways G Basile, A Vetere, J Hu, O Ijaduola, Y Zhang, KC Liu, AM Eltony, ... Cell metabolism 35 (7), 1242-1260. e9, 2023 | 4 | 2023 |
Single-nucleus RNA-Seq reveals singular gene signatures of human ductal cells during adaptation to insulin resistance E Dirice, G Basile, S Kahraman, D Diegisser, J Hu, RN Kulkarni JCI insight 7 (16), 2022 | 4 | 2022 |
Redox Regulation of m6A Methyltransferase METTL3 in Human β-cells Controls the Innate Immune Response in Type 1 Diabetes DF De Jesus, Z Zhang, NK Brown, X Li, MJ Gaffrey, S Kahraman, J Wei, ... bioRxiv, 2023.02. 16.528701, 2023 | 1 | 2023 |
Identification of Pancreatic Elastase Inhibitors That Can Stimulate Beta-Cell Proliferation G Basile, A Vetere, J Hu, B Wagner, R Kulkarni Diabetes 67 (Supplement_1), 2018 | 1 | 2018 |
Mutations in APPL1 gene may contribute to familial diabetes mellitus S Prudente, P Jungtrakoon, A Marucci, O Ludovico, T Mazza, T Hastings, ... Diabetes, 2014 | 1 | 2014 |
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes D F. De Jesus, Z Zhang, NK Brown, X Li, L Xiao, J Hu, MJ Gaffrey, ... Nature Cell Biology, 1-17, 2024 | | 2024 |
198-OR: Pancreatic Elastase Regulates Human Beta-Cell Viability by Impairing the PAR2 Pathway G BASILE, A VETERE, J HU, DF DE JESUS, A CHOUDHARY, ... Diabetes 72 (Supplement_1), 2023 | | 2023 |