Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine RM Pirzgalska, E Seixas, JS Seidman, VM Link, NM Sánchez, I Mahú, ... Nature medicine 23 (11), 1309-1318, 2017 | 397 | 2017 |
Niche-specific reprogramming of epigenetic landscapes drives myeloid cell diversity in nonalcoholic steatohepatitis JS Seidman, TD Troutman, M Sakai, A Gola, NJ Spann, H Bennett, ... Immunity 52 (6), 1057-1074. e7, 2020 | 292 | 2020 |
Liver-derived signals sequentially reprogram myeloid enhancers to initiate and maintain Kupffer cell identity M Sakai, TD Troutman, JS Seidman, Z Ouyang, NJ Spann, Y Abe, KM Ego, ... Immunity 51 (4), 655-670. e8, 2019 | 267 | 2019 |
Expansion of islet-resident macrophages leads to inflammation affecting β cell proliferation and function in obesity W Ying, YS Lee, Y Dong, JS Seidman, M Yang, R Isaac, JB Seo, BH Yang, ... Cell metabolism 29 (2), 457-474. e5, 2019 | 222 | 2019 |
Neutralization of oxidized phospholipids ameliorates non-alcoholic steatohepatitis X Sun, JS Seidman, P Zhao, TD Troutman, NJ Spann, X Que, F Zhou, ... Cell metabolism 31 (1), 189-206. e8, 2020 | 138 | 2020 |
Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages ED Muse, S Yu, CR Edillor, J Tao, NJ Spann, TD Troutman, JS Seidman, ... Proceedings of the National Academy of Sciences 115 (20), E4680-E4689, 2018 | 99 | 2018 |
Exercise and diabetes H Zisser, P Gong, CM Kelley, JS Seidman, MC Riddell International Journal of Clinical Practice 65, 71-75, 2011 | 72 | 2011 |
Dupilumab for bullous pemphigoid with intractable pruritus JS Seidman, DZ Eichenfield, CM Orme Dermatology Online Journal 25 (11), 2019 | 38 | 2019 |
Setd5 haploinsufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice SM Moore, JS Seidman, J Ellegood, R Gao, A Savchenko, TD Troutman, ... Translational psychiatry 9 (1), 24, 2019 | 37 | 2019 |
Alternative fates of paused ribosomes during translation termination JS Seidman, BD Janssen, CS Hayes Journal of Biological Chemistry 286 (36), 31105-31112, 2011 | 28 | 2011 |
Antimicrobial production by perifollicular dermal preadipocytes is essential to the pathophysiology of acne AM O’Neill, MC Liggins, JS Seidman, TH Do, F Li, KJ Cavagnero, ... Science translational medicine 14 (632), eabh1478, 2022 | 27 | 2022 |
Purification of mouse hepatic non-parenchymal cells or nuclei for use in ChIP-seq and other next-generation sequencing approaches TD Troutman, H Bennett, M Sakai, JS Seidman, S Heinz, CK Glass STAR protocols 2 (1), 100363, 2021 | 15 | 2021 |
Skin inflammation activates intestinal stromal fibroblasts and promotes colitis T Dokoshi, JS Seidman, KJ Cavagnero, F Li, MC Liggins, BC Taylor, ... The Journal of Clinical Investigation 131 (21), 2021 | 14 | 2021 |
Genome‐Wide approaches to defining macrophage identity and function GJ Fonseca, JS Seidman, CK Glass Myeloid Cells in Health and Disease: A Synthesis, 553-570, 2017 | 14 | 2017 |
An optimized protocol for rapid, sensitive and robust on-bead ChIP-seq from primary cells L Texari, NJ Spann, TD Troutman, M Sakai, JS Seidman, S Heinz STAR protocols 2 (1), 100358, 2021 | 11 | 2021 |
Nevoid melanoma and eruptive nevi from erlotinib JS Seidman, DZ Eichenfield, CM Orme Dermatology Online Journal 26 (6), 2020 | 6 | 2020 |
Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes H Bennett, TD Troutman, E Zhou, NJ Spann, VM Link, JS Seidman, ... Nature Immunology 24 (11), 1825-1838, 2023 | 3 | 2023 |
RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β-and RNA-dependent co-activator of osteoclast gene expression Y Abe, ER Kofman, M Almeida, Z Ouyang, F Ponte, JR Mueller, ... Molecular Cell 83 (19), 3421-3437. e11, 2023 | 3 | 2023 |
Genetic and functional analyses of Cutibacterium Acnes isolates reveal the association of a linear plasmid with skin inflammation AM O’Neill, KJ Cavagnero, JS Seidman, L Zaramela, Y Chen, F Li, ... Journal of Investigative Dermatology 144 (1), 116-124. e4, 2024 | 2 | 2024 |
Targeting type 2 inflammation for treatment of bullous pemphigoid JS Seidman, DZ Eichenfield, CM Orme Journal of Dermatology and Skin Science 2 (1), 2020 | 2 | 2020 |