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Dr Tao Tan
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CUG-binding protein 1 regulates HSC activation and liver fibrogenesis
X Wu, X Wu, Y Ma, F Shao, Y Tan, T Tan, L Gu, Y Zhou, B Sun, Y Sun, ...
Nature communications 7 (1), 13498, 2016
852016
Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88
F Shao, T Tan, Y Tan, Y Sun, X Wu, Q Xu
Biochemical Pharmacology 115, 94-103, 2016
502016
Role of CXCR3 signaling in response to anti-PD-1 therapy
X Han, Y Wang, J Sun, T Tan, X Cai, P Lin, Y Tan, B Zheng, B Wang, ...
EBioMedicine 48, 169-177, 2019
472019
Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine
Y Hirokawa, J Clarke, M Palmieri, T Tan, D Mouradov, S Li, C Lin, F Li, ...
Communications biology 4 (1), 1067, 2021
172021
The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells
Z Wang, H Hu, L Heitink, K Rogers, Y You, T Tan, CLW Suen, A Garnham, ...
Cell Death & Differentiation 30 (4), 1033-1046, 2023
152023
Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
Z Wang, M Burigotto, S Ghetti, F Vaillant, T Tan, BD Capaldo, M Palmieri, ...
Cancer Discovery 14 (2), 362-379, 2024
102024
Genotype-Tailored ERK/MAPK Pathway and HDAC Inhibition Rewires the Apoptotic Rheostat to Trigger Colorectal Cancer Cell Death
LJ Jenkins, IY Luk, WD Fairlie, EF Lee, M Palmieri, KL Schoffer, T Tan, ...
Molecular Cancer Therapeutics 22 (1), 52-62, 2023
82023
A fumigaclavine C isostere alleviates Th1-mediated experimental colitis via competing with IFN-γ for binding to IFN-γ receptor 1
Y Tan, X Wu, J Sun, W Guo, F Gong, F Shao, T Tan, Y Cao, B Zheng, Y Gu, ...
Biochemical Pharmacology 123, 63-72, 2017
72017
Low-viscosity matrix suspension culture for human colorectal epithelial organoids and tumoroids
T Tan, Y Hirokawa, J Clarke, A Sakthianandeswaren, OM Sieber
Bio-protocol 12 (8), e4394-e4394, 2022
42022
Unified framework for patient-derived, tumor-organoid-based predictive testing of standard-of-care therapies in metastatic colorectal cancer
T Tan, D Mouradov, M Lee, G Gard, Y Hirokawa, S Li, C Lin, F Li, H Luo, ...
Cell Reports Medicine 4 (12), 2023
32023
BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer
J Mariadason, L Jenkins, I Luk, F Chionh, T Tan, K Needham, N Vukelic, ...
12023
BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer
LJ Jenkins, IY Luk, F Chionh, T Tan, K Needham, J Ayton, CM Reehorst, ...
Cell Death & Disease 15 (3), 183, 2024
2024
Abstract C043: Discovery of new drug combinations for metastatic colorectal cancer
EJ In, T Tan, D Mouradov, A Sakthianandeswaren, A Au, K Lowes, ...
Molecular Cancer Therapeutics 22 (12_Supplement), C043-C043, 2023
2023
FORECAST-1: Feasibility of organoid response assessment to define effective treatments for patients with colorectal cancer after failure of standard therapy.
M Lee, G Gard, J Tie, NC Tebbutt, T Tan, A Jalali, B Lee, O Sieber, ...
Journal of Clinical Oncology 40 (16_suppl), 3583-3583, 2022
2022
FORECAST-1: Feasibility of organoid response assessment to define effective treatments for patients with colorectal cancer after failure of standard therapy.
G Gard, M Lee, Y Hirokawa, J Tie, J Clarke, NC Tebbutt, T Tan, A Jalali, ...
Journal of Clinical Oncology 39 (15_suppl), e15571-e15571, 2021
2021
Dual MAPK and HDAC inhibition rewires the apoptotic rheostat to trigger colorectal cancer cell death
LJ Jenkins, IY Luk, M Palmieri, WD Fairlie, EF Lee, KL Schoffer, T Tan, ...
bioRxiv, 2021.02. 15.431252, 2021
2021
Metastatic colorectal cancer cells harness nonsense-mediated mRNA decay for immune evasion
X Wu, T Tan, Q Xu
The Journal of Immunology 204 (1_Supplement), 242.17-242.17, 2020
2020
Resistance to anti-PD-1 therapy is associated with the retention of CXCR3+ CD4+ CD8-T cells in blood
X Han, T Tan, J Sun, X Chen, X Cai, P Lin, Y Tan, B Wang, Y Wang, ...
Annals of Oncology 29, viii425-viii426, 2018
2018
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Articles 1–18