| Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands HM O'Hagan, W Wang, S Sen, CDS Shields, SS Lee, YW Zhang, ... Cancer cell 20 (5), 606-619, 2011 | 586 | 2011 |
| Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island HM O'Hagan, HP Mohammad, SB Baylin PLoS genetics 4 (8), e1000155, 2008 | 439 | 2008 |
| Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus MD Galigniana, JM Harrell, HM O'Hagen, M Ljungman, WB Pratt Journal of Biological Chemistry 279 (21), 22483-22489, 2004 | 202 | 2004 |
| Chronic cigarette smoke-induced epigenomic changes precede sensitization of bronchial epithelial cells to single-step transformation by KRAS mutations M Vaz, SY Hwang, I Kagiampakis, J Phallen, A Patil, HM O'Hagan, ... Cancer cell 32 (3), 360-376. e6, 2017 | 190 | 2017 |
| The role of inflammation and inflammatory mediators in the development, progression, metastasis, and chemoresistance of epithelial ovarian cancer SS Savant, S Sriramkumar, HM O’Hagan Cancers 10 (8), 251, 2018 | 165 | 2018 |
| RPA and ATR link transcriptional stress to p53 FA Derheimer, HM O'Hagan, HM Krueger, S Hanasoge, MT Paulsen, ... Proceedings of the National Academy of Sciences 104 (31), 12778-12783, 2007 | 144 | 2007 |
| Accumulation of soluble and nucleolar-associated p53 proteins following cellular stress SA Klibanov, HM O’Hagan, M Ljungman Journal of cell science 114 (10), 1867-1873, 2001 | 100 | 2001 |
| Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation HP Mohammad, Y Cai, KM McGarvey, H Easwaran, L Van Neste, JE Ohm, ... Cancer research 69 (15), 6322-6330, 2009 | 97 | 2009 |
| Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage N Ding, EM Bonham, BE Hannon, TR Amick, SB Baylin, HM O'Hagan Journal of molecular cell biology 8 (3), 244-254, 2016 | 94 | 2016 |
| Frequent inactivation of cysteine dioxygenase type 1 contributes to survival of breast cancer cells and resistance to anthracyclines J Jeschke, HM O'Hagan, W Zhang, R Vatapalli, MF Calmon, L Danilova, ... Clinical Cancer Research 19 (12), 3201-3211, 2013 | 94 | 2013 |
| Reduction of Murine Colon Tumorigenesis Driven by Enterotoxigenic Bacteroides fragilis Using Cefoxitin Treatment CE DeStefano Shields, SW Van Meerbeke, F Housseau, H Wang, ... The Journal of infectious diseases 214 (1), 122-129, 2016 | 86 | 2016 |
| Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation M Ljungman, HM O'Hagan, MT Paulsen Oncogene 20 (42), 5964-5971, 2001 | 83 | 2001 |
| Epigenetic silencing of neurofilament genes promotes an aggressive phenotype in breast cancer MF Calmon, J Jeschke, W Zhang, M Dhir, C Siebenkäs, A Herrera, ... Epigenetics 10 (7), 622-632, 2015 | 79 | 2015 |
| Dietary antioxidants remodel DNA methylation patterns in chronic disease M Beetch, S Harandi‐Zadeh, K Shen, K Lubecka, DD Kitts, HM O'Hagan, ... British journal of pharmacology 177 (6), 1382-1408, 2020 | 74 | 2020 |
| LSD1 and Aberrant DNA Methylation Mediate Persistence of Enteroendocrine Progenitors That Support BRAF-Mutant Colorectal Cancer SA Miller, RA Policastro, S Sriramkumar, T Lai, TD Huntington, ... Cancer research 81 (14), 3791-3805, 2021 | 68 | 2021 |
| Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy CE DeStefano Shields, JR White, L Chung, A Wenzel, JL Hicks, AJ Tam, ... Cancer discovery 11 (7), 1792-1807, 2021 | 60 | 2021 |
| Chromatin modifications during repair of environmental exposure‐induced DNA damage: A potential mechanism for stable epigenetic alterations HM O'Hagan Environmental and molecular mutagenesis 55 (3), 278-291, 2014 | 58 | 2014 |
| Mismatch repair proteins initiate epigenetic alterations during inflammation-driven tumorigenesis AR Maiuri, M Peng, R Podicheti, S Sriramkumar, CM Kamplain, DB Rusch, ... Cancer research 77 (13), 3467-3478, 2017 | 55 | 2017 |
| Nuclear accumulation of p53 following inhibition of transcription is not due to diminished levels of MDM2 HM O'Hagan, M Ljungman Oncogene 23 (32), 5505-5512, 2004 | 48 | 2004 |
| Interplay between inflammation and epigenetic changes in cancer AR Maiuri, HM O’hagan Progress in Molecular Biology and Translational Science 144, 69-117, 2016 | 43 | 2016 |
Stephen B. BaylinJohns Hopkins University, Van Andel Research InstituteVerified email at vai.org
