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Phyllis Chen
Phyllis Chen
Verified email at cam.ac.uk
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Cited by
Year
Microbial exposure during early human development primes fetal immune cells
A Mishra, GC Lai, LJ Yao, TT Aung, N Shental, A Rotter-Maskowitz, ...
Cell 184 (13), 3394-3409. e20, 2021
1792021
Immunome perturbation is present in patients with juvenile idiopathic arthritis who are in remission and will relapse upon anti-TNFα withdrawal
JY Leong, P Chen, JG Yeo, F Ally, C Chua, SN Hazirah, SL Poh, L Pan, ...
Annals of the Rheumatic Diseases 78 (12), 1712-1721, 2019
192019
Compartmentalization and persistence of dominant (regulatory) T cell clones indicates antigen skewing in juvenile idiopathic arthritis
G Mijnheer, NH Servaas, JY Leong, A Boltjes, E Spierings, P Chen, L Lai, ...
Elife 12, e79016, 2023
52023
Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole-slide imaging and accurate segmentation
EN Kim, PZ Chen, D Bressan, M Tripathi, A Miremadi, M di Pietro, ...
Cell Reports Methods 3 (10), 2023
32023
Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole slide imaging with accurate single-cell segmentation
EN Kim, PZ Chen, D Bressan, M Tripathi, A Miremadi, M di Pietro, ...
bioRxiv, 2023
12023
AB0007 DYNAMIC INTERPLAY OF FUNCTIONALLY DISCORDANT CD4+ HLA-DR+ SUBSETS WITH A COMMON PATHOLOGICAL ONTOGENIC ORIGIN IN HUMAN ARTHRITIS
JY Leong, P Kumar, AJM Lim, SH Tay, S Hazirah, JG Yeo, C Chua, ...
Annals of the Rheumatic Diseases 82 (Suppl 1), 1182-1183, 2023
2023
COMPARTMENTALIZATION, PERSISTENCE AND CONSERVED SHARED MOTIFS OF DOMINANT (REGULATORY) T CELL CLONES IN AUTOIMMUNE INFLAMMATION
G Mijnheer, N Servaas, L Lutter, JY Leong, E Spierings, P Chen, A Petrelli, ...
Clinical and Experimental Rheumatology 39 (5), 1153-1154, 2021
2021
THU0047 THE SYNOVIUM REWIRES AN IMMUNOLOGICAL RHEOSTAT THAT DEFINES TWO FUNCTIONALLY DISPARATE PATHOGENIC CD4+ HLA-DR+ SUBSETS IN HUMAN ARTHRITIS
JY Leong, P Kumar, G Mijnheer, P Chen, JG Yeo, SH Tay, C Chua, ...
Annals of the Rheumatic Diseases 79 (Suppl 1), 236-236, 2020
2020
SAT0496 INTERROGATING THE CIRCULATORY IMMUNE ARCHITECTURE OF ENTHESITIS-RELATED ARTHRITIS
SH Tay, JY Leong, M Wasser, AJM Lim, P Chen, JG Yeo, T Arkachaisri, ...
Annals of the Rheumatic Diseases 79 (Suppl 1), 1204-1204, 2020
2020
SAT0024 TRANSCRIPTOMIC PROFILING OF THE MICROENVIRONMENT DRIVEN RE-SHAPING OF PATHOGENIC CIRCULATORY AND SYNOVIAL HLA-DR+ CD4 T SUBSETS IN ACTIVE JUVENILE IDIOPATHIC ARTHRITIC …
J yao Leong, P Kumar, P Chen, JG Yeo, C Chua, SN Hazirah, ...
Annals of the Rheumatic Diseases 78 (Suppl 2), 1076-1077, 2019
2019
An immunome perturbation is present in juvenile idiopathic arthritis patients who are in remission and will relapse upon anti-TNFα withdrawal
JY Leong, P Chen, JG Yeo, F Ally, C Chua, SN Hazirah, SL Poh, L Pan, ...
bioRxiv, 656124, 2019
2019
Microenvironment Driven Re-Shaping of Pathogenic T Effector and Regulatory Subset in Active Juvenile Idiopathic Arthritic Patients
JY Leong, P Kumar, P Chen, JG Yeo, C Chua, SN Hazirah, S Saidin, ...
ARTHRITIS & RHEUMATOLOGY 70, 2018
2018
OP0315 Juvenile idiopathic arthritis patients exhibit persistence in cd4 memory t cells and distinct transcriptomic signature despite biologics therapy
JY Leong, JG Yeo, P Chen, F Ally, C Chua, SN Hazirah, P Lu, L Lai, ...
Annals of the Rheumatic Diseases 77 (Suppl 2), 204-204, 2018
2018
A Novel Regulatory Antigen Presenting B Cell and Memory Regulatory T Cell Subsets Are Enriched during the Quiescent Phase of Childhood Onset Systemic Lupus Erythematosus
JG Yeo, T Arkachaisri, L Das, JHT Tan, JY Leong, YJA Tan, L Lai, L Bathi, ...
ARTHRITIS & RHEUMATOLOGY 69, 2017
2017
Transciptome Profile of Inflammation Inducted Circulating Effector and Regulatory T Cells Is Dominated By HLA-DR Pivoted Functional Networks in Active Juvenile Idiopathic …
JY Leong, S Albani, P Kumar, JG Yeo, P Chen, SN Hazirah, C Chua, ...
ARTHRITIS & RHEUMATOLOGY 69, 2017
2017
Persistence of Pathogenic CD4 Memory T Cells Revealed through Cytometry Time of Flight in Juvenile Idiopathic Arthritic Patients with Disease Resurgence upon Withdrawal of Anti …
JY Leong, JG Yeo, P Chen, L Lai, F Ally, L Bathi, JHT Tan, T Arkachaisri, ...
ARTHRITIS & RHEUMATOLOGY 69, 2017
2017
A Dichotomy of Regulatory Immunome Is Related to Disease Activity in Juvenile Systemic Lupus Erythematosus
JG Yeo, T Arkachaisri, JHT Tan, JY Leong, L Das, L Bathi, P Chen, ...
ARTHRITIS & RHEUMATOLOGY 68, 2016
2016
High Dimensional Interrogation of the T Cell Immunome in Polyarticular Juvenile Idiopathic Arthritis Patients
JY Leong, J Tiong, JG Yeo, L Lai, P Chen, L Bathi, T Arkachaisri, ...
ARTHRITIS & RHEUMATOLOGY 68, 2016
2016
An immunome perturbation is present in juvenile idiopathic arthritis patients who are in remission and will relapse upon anti-TNFɑ withdrawal
JY Leong, P Chen, JG Yeo, F Ally, C Chua, S Nur, SLP Hazirah, L Pan, ...
Compartmentalization and persistence of dominant (regulatory) T cell clones in autoim-mune inflammation
G Mijnheer, JY Leong, A Boltjes, A Eisele, E Spierings, P Chen, L Lai, ...
T cell regulation and adaptation in chronic inflammation, 131, 0
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