Microbial exposure during early human development primes fetal immune cells A Mishra, GC Lai, LJ Yao, TT Aung, N Shental, A Rotter-Maskowitz, ... Cell 184 (13), 3394-3409. e20, 2021 | 179 | 2021 |
Immunome perturbation is present in patients with juvenile idiopathic arthritis who are in remission and will relapse upon anti-TNFα withdrawal JY Leong, P Chen, JG Yeo, F Ally, C Chua, SN Hazirah, SL Poh, L Pan, ... Annals of the Rheumatic Diseases 78 (12), 1712-1721, 2019 | 19 | 2019 |
Compartmentalization and persistence of dominant (regulatory) T cell clones indicates antigen skewing in juvenile idiopathic arthritis G Mijnheer, NH Servaas, JY Leong, A Boltjes, E Spierings, P Chen, L Lai, ... Elife 12, e79016, 2023 | 5 | 2023 |
Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole-slide imaging and accurate segmentation EN Kim, PZ Chen, D Bressan, M Tripathi, A Miremadi, M di Pietro, ... Cell Reports Methods 3 (10), 2023 | 3 | 2023 |
Dual-modality imaging of immunofluorescence and imaging mass cytometry for whole slide imaging with accurate single-cell segmentation EN Kim, PZ Chen, D Bressan, M Tripathi, A Miremadi, M di Pietro, ... bioRxiv, 2023 | 1 | 2023 |
AB0007 DYNAMIC INTERPLAY OF FUNCTIONALLY DISCORDANT CD4+ HLA-DR+ SUBSETS WITH A COMMON PATHOLOGICAL ONTOGENIC ORIGIN IN HUMAN ARTHRITIS JY Leong, P Kumar, AJM Lim, SH Tay, S Hazirah, JG Yeo, C Chua, ... Annals of the Rheumatic Diseases 82 (Suppl 1), 1182-1183, 2023 | | 2023 |
COMPARTMENTALIZATION, PERSISTENCE AND CONSERVED SHARED MOTIFS OF DOMINANT (REGULATORY) T CELL CLONES IN AUTOIMMUNE INFLAMMATION G Mijnheer, N Servaas, L Lutter, JY Leong, E Spierings, P Chen, A Petrelli, ... Clinical and Experimental Rheumatology 39 (5), 1153-1154, 2021 | | 2021 |
THU0047 THE SYNOVIUM REWIRES AN IMMUNOLOGICAL RHEOSTAT THAT DEFINES TWO FUNCTIONALLY DISPARATE PATHOGENIC CD4+ HLA-DR+ SUBSETS IN HUMAN ARTHRITIS JY Leong, P Kumar, G Mijnheer, P Chen, JG Yeo, SH Tay, C Chua, ... Annals of the Rheumatic Diseases 79 (Suppl 1), 236-236, 2020 | | 2020 |
SAT0496 INTERROGATING THE CIRCULATORY IMMUNE ARCHITECTURE OF ENTHESITIS-RELATED ARTHRITIS SH Tay, JY Leong, M Wasser, AJM Lim, P Chen, JG Yeo, T Arkachaisri, ... Annals of the Rheumatic Diseases 79 (Suppl 1), 1204-1204, 2020 | | 2020 |
SAT0024 TRANSCRIPTOMIC PROFILING OF THE MICROENVIRONMENT DRIVEN RE-SHAPING OF PATHOGENIC CIRCULATORY AND SYNOVIAL HLA-DR+ CD4 T SUBSETS IN ACTIVE JUVENILE IDIOPATHIC ARTHRITIC … J yao Leong, P Kumar, P Chen, JG Yeo, C Chua, SN Hazirah, ... Annals of the Rheumatic Diseases 78 (Suppl 2), 1076-1077, 2019 | | 2019 |
An immunome perturbation is present in juvenile idiopathic arthritis patients who are in remission and will relapse upon anti-TNFα withdrawal JY Leong, P Chen, JG Yeo, F Ally, C Chua, SN Hazirah, SL Poh, L Pan, ... bioRxiv, 656124, 2019 | | 2019 |
Microenvironment Driven Re-Shaping of Pathogenic T Effector and Regulatory Subset in Active Juvenile Idiopathic Arthritic Patients JY Leong, P Kumar, P Chen, JG Yeo, C Chua, SN Hazirah, S Saidin, ... ARTHRITIS & RHEUMATOLOGY 70, 2018 | | 2018 |
OP0315 Juvenile idiopathic arthritis patients exhibit persistence in cd4 memory t cells and distinct transcriptomic signature despite biologics therapy JY Leong, JG Yeo, P Chen, F Ally, C Chua, SN Hazirah, P Lu, L Lai, ... Annals of the Rheumatic Diseases 77 (Suppl 2), 204-204, 2018 | | 2018 |
A Novel Regulatory Antigen Presenting B Cell and Memory Regulatory T Cell Subsets Are Enriched during the Quiescent Phase of Childhood Onset Systemic Lupus Erythematosus JG Yeo, T Arkachaisri, L Das, JHT Tan, JY Leong, YJA Tan, L Lai, L Bathi, ... ARTHRITIS & RHEUMATOLOGY 69, 2017 | | 2017 |
Transciptome Profile of Inflammation Inducted Circulating Effector and Regulatory T Cells Is Dominated By HLA-DR Pivoted Functional Networks in Active Juvenile Idiopathic … JY Leong, S Albani, P Kumar, JG Yeo, P Chen, SN Hazirah, C Chua, ... ARTHRITIS & RHEUMATOLOGY 69, 2017 | | 2017 |
Persistence of Pathogenic CD4 Memory T Cells Revealed through Cytometry Time of Flight in Juvenile Idiopathic Arthritic Patients with Disease Resurgence upon Withdrawal of Anti … JY Leong, JG Yeo, P Chen, L Lai, F Ally, L Bathi, JHT Tan, T Arkachaisri, ... ARTHRITIS & RHEUMATOLOGY 69, 2017 | | 2017 |
A Dichotomy of Regulatory Immunome Is Related to Disease Activity in Juvenile Systemic Lupus Erythematosus JG Yeo, T Arkachaisri, JHT Tan, JY Leong, L Das, L Bathi, P Chen, ... ARTHRITIS & RHEUMATOLOGY 68, 2016 | | 2016 |
High Dimensional Interrogation of the T Cell Immunome in Polyarticular Juvenile Idiopathic Arthritis Patients JY Leong, J Tiong, JG Yeo, L Lai, P Chen, L Bathi, T Arkachaisri, ... ARTHRITIS & RHEUMATOLOGY 68, 2016 | | 2016 |
An immunome perturbation is present in juvenile idiopathic arthritis patients who are in remission and will relapse upon anti-TNFɑ withdrawal JY Leong, P Chen, JG Yeo, F Ally, C Chua, S Nur, SLP Hazirah, L Pan, ... | | |
Compartmentalization and persistence of dominant (regulatory) T cell clones in autoim-mune inflammation G Mijnheer, JY Leong, A Boltjes, A Eisele, E Spierings, P Chen, L Lai, ... T cell regulation and adaptation in chronic inflammation, 131, 0 | | |