| Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK … X Tan, A Xu, T Zhao, Q Zhao, J Zhang, C Fan, Y Deng, A Freywald, ... Scientific reports 8 (1), 3769, 2018 | 67 | 2018 |
| DDX41 is required for cGAS-STING activation against DNA virus infection RS Singh, V Vidhyasagar, S Yang, AB Arna, M Yadav, A Aggarwal, ... Cell reports 39 (8), 2022 | 44 | 2022 |
| TLR9 agonist enhances radiofrequency ablation-induced CTL responses, leading to the potent inhibition of primary tumor growth and lung metastasis A Xu, L Zhang, J Yuan, F Babikr, A Freywald, R Chibbar, M Moser, ... Cellular & Molecular Immunology 16 (10), 820-832, 2019 | 44 | 2019 |
| Simulated microgravity reduces focal adhesions and alters cytoskeleton and nuclear positioning leading to enhanced apoptosis via suppressing FAK/RhoA-mediated mTORC1/NF-κB and … T Zhao, R Li, X Tan, J Zhang, C Fan, Q Zhao, Y Deng, A Xu, KE Lukong, ... International Journal of Molecular Sciences 19 (7), 1994, 2018 | 40 | 2018 |
| Novel exosome-targeted T-cell-based vaccine counteracts T-cell anergy and converts CTL exhaustion in chronic infection via CD40L signaling through the mTORC1 pathway R Wang, A Xu, X Zhang, J Wu, A Freywald, J Xu, J Xiang Cellular & Molecular Immunology 14 (6), 529-545, 2017 | 38 | 2017 |
| IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia A Xu, KK Bhanumathy, J Wu, Z Ye, A Freywald, SC Leary, R Li, J Xiang Cell & Bioscience 6, 1-13, 2016 | 32 | 2016 |
| Distinct roles but cooperative effect of TLR3/9 agonists and PD-1 blockade in converting the immunotolerant microenvironment of irreversible electroporation-ablated tumors F Babikr, J Wan, A Xu, Z Wu, S Ahmed, A Freywald, R Chibbar, Y Wu, ... Cellular & Molecular Immunology 18 (12), 2632-2647, 2021 | 22 | 2021 |
| Heterologous human/rat HER2-specific exosome-targeted T cell vaccine stimulates potent humoral and CTL responses leading to enhanced circumvention of HER2 tolerance in double … Y Xie, J Wu, A Xu, S Ahmeqd, A Sami, R Chibbar, A Freywald, C Zheng, ... Vaccine 36 (11), 1414-1422, 2018 | 22 | 2018 |
| A rationally designed TNF-α epitope-scaffold immunogen induces sustained antibody response and alleviates collagen-induced arthritis in mice L Zhang, J Wang, A Xu, C Zhong, W Lu, L Deng, R Li PLoS one 11 (9), e0163080, 2016 | 22 | 2016 |
| Enhanced suppression of polyclonal CD8+25+ regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes C Mu, X Zhang, L Wang, A Xu, KA Ahmed, X Pang, R Chibbar, A Freywald, ... Journal of Leucocyte Biology 101 (5), 1221-1231, 2017 | 20 | 2017 |
| Immunogenicity and efficacy of a rationally designed vaccine against vascular endothelial growth factor in mouse solid tumor models A Xu, L Zhang, Y Chen, Z Lin, R Li Cancer Immunology, Immunotherapy 66, 181-192, 2017 | 19 | 2017 |
| Design and synthesis of affinity ligands and relation of their structure with adsorption of proteins L Ye, A Xu, C Cheng, L Zhang, C Huo, F Huang, H Xu, R Li Journal of separation science 34 (22), 3145-3150, 2011 | 14 | 2011 |
| CD40 agonist converting CTL exhaustion via the activation of the mTORC1 pathway enhances PD-1 antagonist action in rescuing exhausted CTLs in chronic infection A Xu, R Wang, A Freywald, K Stewart, S Tikoo, J Xu, C Zheng, J Xiang Biochemical and biophysical research communications 484 (3), 662-667, 2017 | 9 | 2017 |
| Potent immunotherapy against well‐established thymoma using adoptively transferred transgene IL‐6‐engineered dendritic cell‐stimulated CD8+ T‐cells with … K Kalyanasundaram Bhanumathy, B Zhang, Y Xie, A Xu, X Tan, J Xiang The Journal of Gene Medicine 17 (8-9), 153-160, 2015 | 8 | 2015 |
| Prosurvival IL-7–Stimulated Weak Strength of mTORC1-S6K Controls T Cell Memory via Transcriptional FOXO1–TCF1–Id3 and Metabolic AMPKα1–ULK1–ATG7 Pathways A Xu, SC Leary, MF Islam, Z Wu, KK Bhanumathy, A Ara, R Chibbar, ... The Journal of Immunology 208 (1), 155-168, 2022 | 7 | 2022 |
| The energy sensor AMPKα1 is critical in rapamycin-inhibition of mTORC1-S6K-induced T-cell memory A Ara, A Xu, KA Ahmed, SC Leary, MF Islam, Z Wu, R Chibbar, J Xiang International Journal of Molecular Sciences 23 (1), 37, 2021 | 7 | 2021 |
| The Critical Role of AMPKα1 in Regulating Autophagy and Mitochondrial Respiration in IL-15-Stimulated mTORC1Weak Signal-Induced T Cell Memory: An … A Ara, Z Wu, A Xu, KA Ahmed, SC Leary, MF Islam, R Chibbar, Y Wu, ... International Journal of Molecular Sciences 23 (17), 9534, 2022 | 4 | 2022 |
| Novel T-cell-based vaccines via arming polyclonal CD4+ T cells with antigen-specific exosomes A Xu, A Freywald, J Xiang Immunotherapy 8 (11), 1265-1269, 2016 | 4 | 2016 |
| Transgene IL-21-Engineered T Cell-Based Vaccine Potently Converts CTL Exhaustion via the Activation of the mTORC1 Pathway in Chronic Infection A Xu, X Zhang, R Chibbar, A Freywald, S Tikoo, C Zheng, J Xiang World Journal of Vaccines 9 (1), 1-21, 2019 | 3* | 2019 |
| CD8+ memory T-cell inflation renders compromised CD4+ T-cell-dependent CD8+ T-cell immunity via naïve T-cell anergy A Xu, A Freywald, Y Xie, Z Li, J Xiang ImmunoTargets and Therapy, 39-49, 2017 | 1 | 2017 |
