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Tom Jongens
Tom Jongens
Associate Professor, University of Pennsylvania
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Year
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
P Jin, DC Zarnescu, S Ceman, M Nakamoto, J Mowrey, TA Jongens, ...
Nature neuroscience 7 (2), 113-117, 2004
8082004
Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome
SMJ McBride, CH Choi, Y Wang, D Liebelt, E Braunstein, D Ferreiro, ...
Neuron 45 (5), 753-764, 2005
5542005
Characterization of dFMR1, a Drosophila melanogaster Homolog of the Fragile X Mental Retardation Protein
L Wan, TC Dockendorff, TA Jongens, G Dreyfuss
Molecular and cellular biology 20 (22), 8536-8547, 2000
3402000
A central role for microtubules in the differentiation of Drosophila oocytes
WE Theurkauf, BM Alberts, YN Jan, TA Jongens
Development 118 (4), 1169-1180, 1993
3401993
Drosophila lacking dfmr1 activity show defects in circadian output and fail to maintain courtship interest
TC Dockendorff, HS Su, SMJ McBride, Z Yang, CH Choi, KK Siwicki, ...
Neuron 34 (6), 973-984, 2002
3362002
Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability
Y Kirino, N Kim, M de Planell-Saguer, E Khandros, S Chiorean, PS Klein, ...
Nature cell biology 11 (5), 652-658, 2009
2792009
The germ cell-less gene product: a posteriorly localized component necessary for germ cell development in Drosophila
TA Jongens, B Hay, LY Jan, YN Jan
Cell 70 (4), 569-584, 1992
2211992
Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization
Y Kirino, A Vourekas, N Sayed, F de Lima Alves, T Thomson, P Lasko, ...
Rna 16 (1), 70-78, 2010
1352010
Germ cell-less encodes a cell type-specific nuclear pore-associated protein and functions early in the germ-cell specification pathway of Drosophila.
TA Jongens, LD Ackerman, JR Swedlow, LY Jan, YN Jan
Genes & Development 8 (18), 2123-2136, 1994
1341994
Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment
CH Choi, BP Schoenfeld, AJ Bell, P Hinchey, M Kollaros, MJ Gertner, ...
Brain research 1380, 106-119, 2011
1152011
The Drosophila fragile X protein functions as a negative regulator in the orb autoregulatory pathway
A Costa, Y Wang, TC Dockendorff, H Erdjument-Bromage, P Tempst, ...
Developmental cell 8 (3), 331-342, 2005
1152005
Transcriptional silencing and translational control: key features of early germline development
JL Leatherman, TA Jongens
Bioessays 25 (4), 326-335, 2003
1102003
Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome
C Gross, CW Chang, SM Kelly, A Bhattacharya, SMJ McBride, ...
Cell reports 11 (5), 727-736, 2015
1072015
Arginine methylation of vasa protein is conserved across phyla
Y Kirino, A Vourekas, N Kim, F de Lima Alves, J Rappsilber, PS Klein, ...
Journal of Biological Chemistry 285 (11), 8148-8154, 2010
1012010
Insulin signaling misregulation underlies circadian and cognitive deficits in a Drosophila fragile X model
RE Monyak, D Emerson, BP Schoenfeld, X Zheng, DB Chambers, ...
Molecular psychiatry 22 (8), 1140-1148, 2017
952017
Modulation of dADAR-dependent RNA editing by the Drosophila fragile X mental retardation protein
B Bhogal, JE Jepson, YA Savva, ASR Pepper, RA Reenan, TA Jongens
Nature neuroscience 14 (12), 1517-1524, 2011
932011
Mitochondrial dynamics: Shaping and remodeling an organelle network
AR Fenton, TA Jongens, ELF Holzbaur
Current opinion in cell biology 68, 28-36, 2021
892021
Fragile X protein functions with lgl and the par complex in flies and mice
DC Zarnescu, P Jin, J Betschinger, M Nakamoto, Y Wang, TC Dockendorff, ...
Developmental cell 8 (1), 43-52, 2005
882005
germ cell-less acts to repress transcription during the establishment of the Drosophila germ cell lineage
JL Leatherman, L Levin, J Boero, TA Jongens
Current Biology 12 (19), 1681-1685, 2002
882002
germ cell-less is required only during the establishment of the germ cell lineage of Drosophila and has activities which are dependent and independent of its localization to …
SE Robertson, TC Dockendorff, JL Leatherman, DL Faulkner, TA Jongens
Developmental biology 215 (2), 288-297, 1999
741999
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