The effect of lipidation and glycosylation on short cationic antimicrobial peptides E Grimsey, DWP Collis, R Mikut, K Hilpert Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (8), 183195, 2020 | 69 | 2020 |
Chlorpromazine and amitriptyline are substrates and inhibitors of the AcrB multidrug efflux pump EM Grimsey, C Fais, RL Marshall, V Ricci, ML Ciusa, JW Stone, A Ivens, ... MBio 11 (3), 10.1128/mbio. 00465-20, 2020 | 58 | 2020 |
Screening and optimizing antimicrobial peptides by using SPOT-synthesis PM López-Pérez, E Grimsey, L Bourne, R Mikut, K Hilpert Frontiers in chemistry 5, 25, 2017 | 49 | 2017 |
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB E Reading, Z Ahdash, C Fais, V Ricci, X Wang-Kan, E Grimsey, J Stone, ... Nature communications 11 (1), 5565, 2020 | 47 | 2020 |
Do phenothiazines possess antimicrobial and efflux inhibitory properties? EM Grimsey, LJV Piddock FEMS Microbiology Reviews 43 (6), 577-590, 2019 | 41 | 2019 |
Overexpression of RamA, which regulates production of the multidrug resistance efflux pump AcrAB-TolC, increases mutation rate and influences drug resistance phenotype EM Grimsey, N Weston, V Ricci, JW Stone, LJV Piddock Antimicrobial Agents and Chemotherapy 64 (4), 10.1128/aac. 02460-19, 2020 | 37 | 2020 |
Temperature sensitive point mutations in fission yeast tropomyosin have long range effects on the stability and function of the actin-tropomyosin copolymer CA Johnson, HR Brooker, I Gyamfi, J O'Brien, B Ashley, JE Brazier, ... Biochemical and biophysical research communications 506 (2), 339-346, 2018 | 11 | 2018 |
Exposure of Escherichia coli to antibiotic-efflux pump inhibitor combinations in a pharmacokinetic model: impact on bacterial clearance and drug resistance AP MacGowan, MLG Attwood, AR Noel, R Barber, Z Aron, TJ Opperman, ... Journal of Antimicrobial Chemotherapy 78 (12), 2869-2877, 2023 | 3 | 2023 |
Chlorpromazine and amitriptyline are substrates and inhibitors of the AcrB multidrug efflux pump. mBio 11: e00465-20 EM Grimsey, C Fais, RL Marshall, V Ricci, ML Ciusa, JW Stone, A Ivens, ... | 3 | 2020 |
Perturbed structural dynamics underlie inhibition and altered specificity of the multidrug efflux pump AcrB E Reading, Z Ahdash, C Fais, V Ricci, XW Kan, E Grimsey, J Stone, ... bioRxiv, 2020.04. 27.063511, 2020 | 1 | 2020 |
Understanding the mode of action of compounds that are suggested to possess efflux inhibitory properties EM Grimsey University of Birmingham, 2021 | | 2021 |
Temperature sensitive point mutations in fission yeast tropomyosin have long range effects on protein stability that destabilise the actin-tropomyosin copolymer in vitro and in … CA Johnson, HR Brooker, I Gyamfi, J O'Brien, B Ashley, JE Brazier, ... Biochemical and biophysical research communications, 2017 | | 2017 |