| Mitochondria “fuel” breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells F Sotgia, D Whitaker-Menezes, UE Martinez-Outschoorn, A Tsirigos, ... Cell Cycle 11 (23), 3-2, 2012 | 184 | 2012 |
| WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate AW Leung, B Murdoch, AF Salem, MS Prasad, GA Gomez, ... Development 143 (3), 398-410, 2016 | 154 | 2016 |
| Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells AF Salem, D Whitaker-Menezes, Z Lin, UE Martinez-Outschoorn, ... Cell cycle 11 (13), 2545-2559, 2012 | 126 | 2012 |
| Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance AF Salem, D Whitaker-Menezes, A Howell, F Sotgia, MP Lisanti Cell cycle 11 (22), 4174-4180, 2012 | 125 | 2012 |
| Covalent inhibitors of protein–protein interactions targeting lysine, tyrosine, or histidine residues L Gambini, C Baggio, P Udompholkul, J Jossart, AF Salem, JJP Perry, ... Journal of medicinal chemistry 62 (11), 5616-5627, 2019 | 101 | 2019 |
| Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment AF Salem, MS Al-Zoubi, D Whitaker-Menezes, UE Martinez-Outschoorn, ... Cell Cycle 12 (5), 818-825, 2013 | 73 | 2013 |
| Reduction of circulating Cancer cells and metastases in breast-Cancer models by a potent EphA2-agonistic peptide–drug conjugate AF Salem, S Wang, S Billet, JF Chen, P Udompholkul, L Gambini, ... Journal of medicinal chemistry 61 (5), 2052-2061, 2018 | 58 | 2018 |
| Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition AF Salem, G Bonuccelli, G Bevilacqua, H Arafat, RG Pestell, F Sotgia, ... Cell Cycle 10 (21), 3692-3700, 2011 | 56 | 2011 |
| Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1α, autophagy and ketone body production AF Salem, A Howell, M Sartini, F Sotgia, MP Lisanti Cell Cycle 11 (22), 4167-4173, 2012 | 55 | 2012 |
| Characterization of cardiac glycoside natural products as potent inhibitors of DNA double-strand break repair by a whole-cell double immunofluorescence assay YV Surovtseva, V Jairam, AF Salem, RK Sundaram, RS Bindra, ... Journal of the American Chemical Society 138 (11), 3844-3855, 2016 | 54 | 2016 |
| Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors AG Goglia, R Delsite, AN Luz, D Shahbazian, AF Salem, RK Sundaram, ... Molecular cancer therapeutics 14 (2), 326-342, 2015 | 49 | 2015 |
| Aryl-fluorosulfate-based lysine covalent pan-inhibitors of apoptosis protein (IAP) antagonists with cellular efficacy C Baggio, P Udompholkul, L Gambini, AF Salem, J Jossart, JJP Perry, ... Journal of medicinal chemistry 62 (20), 9188-9200, 2019 | 46 | 2019 |
| Potent and selective EphA4 agonists for the treatment of ALS B Wu, SK De, A Kulinich, AF Salem, J Koeppen, R Wang, E Barile, ... Cell chemical biology 24 (3), 293-305, 2017 | 43 | 2017 |
| Involvement of osteopontin in the matrix-degrading and proangiogenic changes mediated by nicotine in pancreatic cancer cells M Lazar, J Sullivan, G Chipitsyna, Q Gong, CY Ng, AF Salem, T Aziz, ... Journal of gastrointestinal surgery 14, 1566-1577, 2010 | 41 | 2010 |
| Design of potent pan-IAP and Lys-covalent XIAP selective inhibitors using a thermodynamics driven approach C Baggio, L Gambini, P Udompholkul, AF Salem, A Aronson, A Dona, ... Journal of medicinal chemistry 61 (14), 6350-6363, 2018 | 40 | 2018 |
| hBfl-1/hNOXA interaction studies provide new insights on the role of Bfl-1 in cancer cell resistance and for the design of novel anticancer agents E Barile, GD Marconi, SK De, C Baggio, L Gambini, AF Salem, ... ACS chemical biology 12 (2), 444-455, 2017 | 36 | 2017 |
| Structure-Based Design of Novel EphA2 Agonistic Agents with Nanomolar Affinity in Vitro and in Cell L Gambini, AF Salem, P Udompholkul, XF Tan, C Baggio, N Shah, ... ACS chemical biology 13 (9), 2633-2644, 2018 | 26 | 2018 |
| Creating a tumor-resistant microenvironment: cell-mediated delivery of TNFα completely prevents breast cancer tumor formation in vivo M Al-Zoubi, AF Salem, UE Martinez-Outschoorn, D Whitaker-Menezes, ... Cell Cycle 12 (3), 480-490, 2013 | 23 | 2013 |
| Induction of monocyte chemoattractant protein-1 by nicotine in pancreatic ductal adenocarcinoma cells: role of osteopontin M Lazar, J Sullivan, G Chipitsyna, T Aziz, AF Salem, Q Gong, A Witkiewicz, ... Surgery 148 (2), 298-309, 2010 | 19 | 2010 |
| Prostate cancer metastases are strongly inhibited by agonistic Epha2 ligands in an orthotopic mouse model AF Salem, L Gambini, S Billet, Y Sun, H Oshiro, M Zhao, RM Hoffman, ... Cancers 12 (10), 2854, 2020 | 18 | 2020 |
