| Metabolic modulation of clear-cell renal cell carcinoma with dichloroacetate, an inhibitor of pyruvate dehydrogenase kinase A Kinnaird, P Dromparis, B Saleme, V Gurtu, K Watson, R Paulin, ... European urology 69 (4), 734-744, 2016 | 77 | 2016 |
| FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression K Gopal, B Saleme, R Al Batran, H Aburasayn, A Eshreif, KL Ho, WK Ma, ... American Journal of Physiology-Heart and Circulatory Physiology 313 (3 …, 2017 | 63 | 2017 |
| Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity B Saleme, V Gurtu, Y Zhang, A Kinnaird, AE Boukouris, K Gopal, ... Science translational medicine 11 (478), eaau8866, 2019 | 60 | 2019 |
| Pimozide alleviates hyperglycemia in diet-induced obesity by inhibiting skeletal muscle ketone oxidation R Al Batran, K Gopal, ME Capozzi, JJ Chahade, B Saleme, ... Cell Metabolism 31 (5), 909-919. e8, 2020 | 49 | 2020 |
| MFN2-driven mitochondria-to-nucleus tethering allows a non-canonical nuclear entry pathway of the mitochondrial pyruvate dehydrogenase complex SD Zervopoulos, AE Boukouris, B Saleme, A Haromy, S Tejay, ... Molecular Cell 82 (5), 1066-1077. e7, 2022 | 27 | 2022 |
| The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity R Al Batran, K Gopal, H Aburasayn, A Eshreif, M Almutairi, AA Greenwell, ... JCI insight 4 (1), 2019 | 20 | 2019 |
| SNPs for genes encoding the mitochondrial proteins Sirtuin3 and uncoupling protein 2 are associated with disease severity, type 2 diabetes, and outcomes in patients with … Y Zhang, SD Zervopoulos, AE Boukouris, MA Lorenzana‐Carrillo, ... Journal of the American Heart Association 10 (23), e020451, 2021 | 8 | 2021 |
| p53‐Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio‐oncology B Saleme, SK Das, Y Zhang, AE Boukouris, MA Lorenzana Carrillo, ... Journal of the American Heart Association 9 (15), e017247, 2020 | 8 | 2020 |
| A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer AE Boukouris, Y Zhang, B Saleme, A Kinnaird, YY Zhao, Y Liu, ... Cell Reports 38 (11), 2022 | 7 | 2022 |
| Interaction with p53 explains a pro-proliferative function for VHL in cancer A Kinnaird, AE Boukouris, B Saleme, P Dromparis, SD Zervopoulos, ... Journal of Molecular Medicine 98, 1269-1278, 2020 | 5 | 2020 |
| TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure MA Lorenzana-Carrillo, K Gopal, NJ Byrne, S Tejay, B Saleme, SK Das, ... Science Translational Medicine 14 (669), eabm3565, 2022 | 4 | 2022 |
| A similar metabolic profile between the failing myocardium and tumor could provide alternative therapeutic targets in chemotherapy-induced cardiotoxicity B Saleme, G Sutendra Frontiers in Cardiovascular Medicine 5, 61, 2018 | 4 | 2018 |
| Loss of the fructose transporter SLC2A5 inhibits cancer cell migration J Groenendyk, K Stoletov, T Paskevicius, W Li, N Dai, M Pujol, E Busaan, ... Frontiers in Cell and Developmental Biology 10, 896297, 2022 | 3 | 2022 |
| cell-specific regulation of the GATA-4/6 transcription factors by the metabolic enzyme PKM2 provides insight into a biologic function essential for cardiac health and survival MAL Carrillo, K Gopal, NJ Byrne, B Saleme, SK Das, S Tejay, Y Zhang, ... Circulation 144, 2021 | 1 | 2021 |
| The Effects of Oxygen-Derived Free-Radical Scavengers During Normothermic Ex-Situ Heart Perfusion X Qi, S Hatami, S Bozso, X Wang, B Saleme, J Nagendran, E Michelakis, ... ASAIO Journal, 10.1097, 2024 | | 2024 |
| N6-methyladenosine bimodal peak signature mediates acute and selective stress translation by specialized cytoskeletal ribosomes via a MARK4-FTO-PKR axis B Saleme | | 2023 |
| Trim35-Mediated Ubiquitination and Degradation of Nuclear PKM2 is Sufficient to Promote Heart Failure MA Lorenzana Carrillo, K Gopal, N Byrne, S Tejay, B Saleme, S Das, ... Circulation 146 (Suppl_1), A9474-A9474, 2022 | | 2022 |
| Cell-Specific Regulation of the GATA-4/6 Transcription Factors by the Metabolic Enzyme PKM2 Provides Insight into a Biologic Function Essential for Cardiac Health and Survival MA Lorenzana Carrillo, K Gopal, NJ Byrne, B Saleme, SK Das, S Tejay, ... Circulation 144 (Suppl_1), A9054-A9054, 2021 | | 2021 |
| Lack of Both Mitochondrial Proteins Sirt3 and Ucp2 in Mice Recapitulates Many Critical Features of Human Pulmonary Arterial Hypertension (PAH), Including Inflammatory … Y Zhang, SD Zervopoulos, AE Boukouris, B Saleme, Y Liu, A Haromy, ... Circulation 142 (Suppl_3), A13575-A13575, 2020 | | 2020 |
| Metabolic Reprogramming and Epigenetic Regulation in Renal Cell Carcinoma A Kinnaird | | 2018 |
