| ANP32E is a histone chaperone that removes H2A.Z from chromatin A Obri, K Ouararhni, C Papin, ML Diebold, K Padmanabhan, M Marek, ... Nature 505 (7485), 648, 2014 | 258 | 2014 |
| Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni M Marek, S Kannan, AT Hauser, MM Mourao, S Caby, V Cura, DA Stolfa, ... PLoS Pathogens 9 (9), e1003645, 2013 | 194 | 2013 |
| Structure-based design and synthesis of novel inhibitors targeting HDAC8 from Schistosoma mansoni for the treatment of schistosomiasis T Heimburg, A Chakrabarti, J Lancelot, M Marek, J Melesina, AT Hauser, ... Journal of Medicinal Chemistry 59 (6), 2423-2435, 2016 | 130 | 2016 |
| Synthesis and biological investigation of oxazole hydroxamates as highly selective histone deacetylase 6 (HDAC6) inhibitors J Senger, J Melesina, M Marek, C Romier, I Oehme, O Witt, W Sippl, ... Journal of Medicinal Chemistry 59 (4), 1545-1555, 2015 | 119 | 2015 |
| Characterization of histone deacetylase 8 (HDAC8) selective inhibition reveals specific active site structural and functional determinants M Marek, TB Shaik, T Heimburg, A Chakrabarti, J Lancelot, ... Journal of Medicinal Chemistry, 2018 | 100 | 2018 |
| Synthesis and biological investigation of phenothiazine-based benzhydroxamic acids as selective histone deacetylase 6 inhibitors K Vögerl, N Ong, J Senger, D Herp, K Schmidtkunz, M Marek, M Müller, ... Journal of Medicinal Chemistry 62 (3), 1138-1166, 2019 | 92 | 2019 |
| Molecular basis and specificity of H2A.Z–H2B recognition and deposition by the histone chaperone YL1 CM Latrick, M Marek, K Ouararhni, C Papin, I Stoll, M Ignatyeva, A Obri, ... Nature Structural & Molecular Biology 23 (4), 309, 2016 | 87 | 2016 |
| Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen Schistosoma mansoni DA Stolfa, M Marek, J Lancelot, AT Hauser, A Walter, E Leproult, ... Journal of Molecular Biology 426 (20), 3442-3453, 2014 | 80 | 2014 |
| Discovery of inhibitors of Schistosoma mansoni HDAC8 by combining homology modeling, virtual screening, and in vitro validation S Kannan, J Melesina, AT Hauser, A Chakrabarti, T Heimburg, ... Journal of Chemical Information and Modeling 54 (10), 3005-3019, 2014 | 75 | 2014 |
| Engineering of baculovirus vectors for the manufacture of virion‐free biopharmaceuticals M Marek, MM van Oers, FF Devaraj, JM Vlak, OW Merten Biotechnology and Bioengineering 108 (5), 1056-1067, 2011 | 74 | 2011 |
| Baculovirus VP80 protein and the F-actin cytoskeleton interact and connect the viral replication factory with the nuclear periphery M Marek, OW Merten, L Galibert, JM Vlak, MM van Oers Journal of Virology, 2011 | 71 | 2011 |
| Engineering the protein dynamics of an ancestral luciferase A Schenkmayerova, GP Pinto, M Toul, M Marek, L Hernychova, ... Nature Communications 12 (1), 3616, 2021 | 64 | 2021 |
| Polyomavirus EGFP‐pseudocapsids: Analysis of model particles for introduction of proteins and peptides into mammalian cells E Bouřa, D Liebl, R Špíšek, J Frič, M Marek, J Štokrová, V Holáň, ... FEBS Letters 579 (29), 6549-6558, 2005 | 60 | 2005 |
| Bioinformatics‐assisted characterization of the ITS1‐5·8S‐ITS2 segments of nuclear rRNA gene clusters, and its exploitation in molecular diagnostics of European crop‐parasitic … M Marek, M Zouhar, O Douda, J Mazakova, P Rysanek Plant Pathology 59 (5), 931-943, 2010 | 52 | 2010 |
| Encyclopedia of Autographa californica nucleopolyhedrovirus genes DPA Cohen, M Marek, BG Davies, JM Vlak, MM Van Oers Virologica Sinica 24, 359-414, 2009 | 49 | 2009 |
| A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing CV Simoben, D Robaa, A Chakrabarti, K Schmidtkunz, M Marek, ... Molecules 23 (3), 566, 2018 | 45 | 2018 |
| Alkoxyurea-based histone deacetylase inhibitors increase cisplatin potency in chemoresistant cancer cell lines K Stenzel, A Hamacher, FK Hansen, CGW Gertzen, J Senger, ... Journal of Medicinal Chemistry 60 (13), 5334-5348, 2017 | 44 | 2017 |
| Light-emitting dehalogenases: reconstruction of multi-functional biocatalysts R Chaloupkova, V Liskova, M Toul, K Markova, E Sebestova, ... ACS Catalysis, 2019 | 40 | 2019 |
| Analysis of ITS sequences of nuclear rDNA and development of a PCR-based assay for the rapid identification of the stem nematode Ditylenchus dipsaci (Nematoda: Anguinidae) in … M Marek, M Zouhar, P Rysanek, P Havranek Helminthologia 42 (2), 49, 2005 | 40 | 2005 |
| Design, multicomponent synthesis, and anticancer activity of a focused histone deacetylase (HDAC) inhibitor library with peptoid-based cap groups V Krieger, A Hamacher, CGW Gertzen, J Senger, MRH Zwinderman, ... Journal of Medicinal Chemistry 60 (13), 5493-5506, 2017 | 35 | 2017 |
Manfred JungInstitute of Pharmaceutical Sciences, University of Freiburg; former University of Münster, OttawaVerified email at pharmazie.uni-freiburg.de
