| α-Synuclein, a chemoattractant, directs microglial migration via H2O2-dependent Lyn phosphorylation S Wang, CH Chu, T Stewart, C Ginghina, Y Wang, H Nie, M Guo, B Wilson, ... Proceedings of the National Academy of Sciences 112 (15), E1926-E1935, 2015 | 171 | 2015 |
| Roles of insulin-like growth factor II in cardiomyoblast apoptosis and in hypertensive rat heart with abdominal aorta ligation SD Lee, CH Chu, EJ Huang, MC Lu, JY Liu, CJ Liu, HH Hsu, JA Lin, ... American Journal of Physiology-Endocrinology and Metabolism 291 (2), E306-E314, 2006 | 127 | 2006 |
| Microglial regulation of immunological and neuroprotective functions of astroglia SH Chen, EA Oyarzabal, YF Sung, CH Chu, Q Wang, SL Chen, RB Lu, ... Glia 63 (1), 118-131, 2015 | 118 | 2015 |
| Akt mediates 17β‐estradiol and/or estrogen receptor‐α inhibition of LPS‐induced tumor necresis factor‐α expression and myocardial cell apoptosis by suppressing the JNK1/2‐NFκB … CJ Liu, JF Lo, CH Kuo, CH Chu, LM Chen, FJ Tsai, CH Tsai, BS Tzang, ... Journal of Cellular and Molecular Medicine 13 (9b), 3655-3667, 2009 | 111 | 2009 |
| Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson’s disease models Q Wang, L Qian, SH Chen, CH Chu, B Wilson, E Oyarzabal, S Ali, ... Brain 138 (5), 1247-1262, 2015 | 106 | 2015 |
| IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Gαq interaction and protein kinase C-α/CaMKII … CH Chu, BS Tzang, LM Chen, CH Kuo, YC Cheng, LY Chen, FJ Tsai, ... Journal of Endocrinology 197 (2), 381-390, 2008 | 105 | 2008 |
| ANG II promotes IGF-IIR expression and cardiomyocyte apoptosis by inhibiting HSF1 via JNK activation and SIRT1 degradation CY Huang, WW Kuo, YL Yeh, TJ Ho, JY Lin, DY Lin, CH Chu, FJ Tsai, ... Cell Death & Differentiation 21 (8), 1262-1274, 2014 | 101 | 2014 |
| Lipopolysaccharide induces cellular hypertrophy through calcineurin/NFAT-3 signaling pathway in H9c2 myocardiac cells CJ Liu, YC Cheng, KW Lee, HH Hsu, CH Chu, FJ Tsai, CH Tsai, CY Chu, ... Molecular and cellular biochemistry 313, 167-178, 2008 | 87 | 2008 |
| Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats SL Chen, PL Tao, CH Chu, SH Chen, HE Wu, LF Tseng, JS Hong, RB Lu Journal of Neuroimmune Pharmacology 7, 444-453, 2012 | 83 | 2012 |
| Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin‐induced damage SH Chen, HM Wu, B Ossola, N Schendzielorz, BC Wilson, CH Chu, ... British journal of pharmacology 165 (2), 494-505, 2012 | 82 | 2012 |
| Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91 phox subunit of NADPH … Q Wang, H Zhou, H Gao, SH Chen, CH Chu, B Wilson, JS Hong Journal of neuroinflammation 9, 1-14, 2012 | 76 | 2012 |
| Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase Q Wang, CH Chu, L Qian, SH Chen, B Wilson, E Oyarzabal, L Jiang, S Ali, ... Journal of Neuroscience 34 (37), 12490-12503, 2014 | 74 | 2014 |
| Activation of insulin-like growth factor II receptor induces mitochondrial-dependent apoptosis through Gαq and downstream calcineurin signaling in myocardial cells CH Chu, BS Tzang, LM Chen, CJ Liu, FJ Tsai, CH Tsai, JA Lin, WW Kuo, ... Endocrinology 150 (6), 2723-2731, 2009 | 70 | 2009 |
| Apoptotic effects of over-expressed estrogen receptor-beta on LoVo colon cancer cell is mediated by p53 signalings in a ligand-dependent manner H Hsu, S Cheng, C Wu, C Chu, Y Weng, C Lin, S Lee, H Wu, C Huang, ... Chinese Journal of Physiology 49 (2), 110, 2006 | 70 | 2006 |
| A novel role of microglial NADPH oxidase in mediating extra‐synaptic function of norepinephrine in regulating brain immune homeostasis L Jiang, SH Chen, CH Chu, SJ Wang, E Oyarzabal, B Wilson, V Sanders, ... Glia 63 (6), 1057-1072, 2015 | 64 | 2015 |
| Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases Q Wang, CH Chu, E Oyarzabal, L Jiang, SH Chen, B Wilson, L Qian, ... Glia 62 (12), 2034-2043, 2014 | 61 | 2014 |
| The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese patients with bipolar disorder and schizophrenia SL Chen, SY Lee, YH Chang, SH Chen, CH Chu, TY Wang, PS Chen, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 51, 99-104, 2014 | 55 | 2014 |
| IGF-II/mannose 6-phosphate receptor activation induces metalloproteinase-9 matrix activity and increases plasminogen activator expression in H9c2 cardiomyoblast cells MH Chang, WW Kuo, RJ Chen, MC Lu, FJ Tsai, WH Kuo, LY Chen, ... Journal of molecular endocrinology 41 (2), 65-74, 2008 | 47 | 2008 |
| Histone acetylation is essential for ANG‐II‐induced IGF‐IIR gene expression in H9c2 cardiomyoblast cells and pathologically hypertensive rat heart CH Chu, JF Lo, WS Hu, RB Lu, MH Chang, FJ Tsai, CH Tsai, YS Weng, ... Journal of cellular physiology 227 (1), 259-268, 2012 | 44 | 2012 |
| WWOX phosphorylation, signaling, and role in neurodegeneration CC Liu, PC Ho, IT Lee, YA Chen, CH Chu, CC Teng, SN Wu, CI Sze, ... Frontiers in Neuroscience 12, 563, 2018 | 43 | 2018 |
