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Tenzin Kunchok
Tenzin Kunchok
Whitehead Institute
Verified email at wi.mit.edu
Title
Cited by
Cited by
Year
Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability
MR Sullivan, LV Danai, CA Lewis, SH Chan, DY Gui, T Kunchok, ...
Elife 8, e44235, 2019
4032019
Histidine catabolism is a major determinant of methotrexate sensitivity
N Kanarek, HR Keys, JR Cantor, CA Lewis, SH Chan, T Kunchok, ...
Nature 559 (7715), 632-636, 2018
2752018
Dihydroxyacetone phosphate signals glucose availability to mTORC1
JM Orozco, PA Krawczyk, SM Scaria, AL Cangelosi, SH Chan, T Kunchok, ...
Nature metabolism 2 (9), 893-901, 2020
1612020
Fumarate is a terminal electron acceptor in the mammalian electron transport chain
JB Spinelli, PC Rosen, HG Sprenger, AM Puszynska, JL Mann, ...
Science 374 (6572), 1227-1237, 2021
1202021
MCART1/SLC25A51 is required for mitochondrial NAD transport
N Kory, J uit de Bos, S van der Rijt, N Jankovic, M Güra, N Arp, IA Pena, ...
Science advances 6 (43), eabe5310, 2020
1132020
MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo
EC Bayraktar, L Baudrier, C Özerdem, CA Lewis, SH Chan, T Kunchok, ...
Proceedings of the National Academy of Sciences 116 (1), 303-312, 2019
882019
Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction
KJ Condon, JM Orozco, CH Adelmann, JB Spinelli, PW van der Helm, ...
Proceedings of the National Academy of Sciences 118 (4), e2022120118, 2021
792021
MFSD12 mediates the import of cysteine into melanosomes and lysosomes
CH Adelmann, AK Traunbauer, B Chen, KJ Condon, SH Chan, T Kunchok, ...
Nature 588 (7839), 699-704, 2020
652020
CLN3 is required for the clearance of glycerophosphodiesters from lysosomes
NN Laqtom, W Dong, UN Medoh, AL Cangelosi, V Dharamdasani, ...
Nature 609 (7929), 1005-1011, 2022
462022
Methionine synthase is essential for cancer cell proliferation in physiological folate environments
MR Sullivan, AM Darnell, MF Reilly, T Kunchok, L Joesch-Cohen, ...
Nature metabolism 3 (11), 1500-1511, 2021
412021
Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine
AL Cangelosi, AM Puszynska, JM Roberts, A Armani, TP Nguyen, ...
Science 377 (6601), 47-56, 2022
242022
Manipulating mitochondrial electron flow enhances tumor immunogenicity
KC Mangalhara, SK Varanasi, MA Johnson, MJ Burns, GR Rojas, ...
Science 381 (6664), 1316-1323, 2023
172023
Screening in serum-derived medium reveals differential response to compounds targeting metabolism
KL Abbott, A Ali, D Casalena, BT Do, R Ferreira, JH Cheah, CK Soule, ...
Cell chemical biology 30 (9), 1156-1168. e7, 2023
82023
MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis
VV Phadnis, J Snider, V Varadharajan, I Ramachandiran, AA Deik, ...
Cell reports 42 (9), 2023
42023
Cancer tissue of origin constrains the growth and metabolism of metastases
S Sivanand, Y Gultekin, PS Winter, SY Vermeulen, K Tchourine, ...
bioRxiv, 2022.08. 17.504141, 2022
42022
Quantification of microenvironmental metabolites in murine cancer models reveals determinants of tumor nutrient availability
MR Sullivan, LV Danai, CA Lewis, SH Chan, DY Gui, T Kunchok, ...
bioRxiv, 492652, 2018
32018
Author Correction: Histidine catabolism is a major determinant of methotrexate sensitivity
N Kanarek, HR Keys, JR Cantor, CA Lewis, SH Chan, T Kunchok, ...
Nature 602 (7895), E17-E18, 2022
22022
MMD scaffolds ACSL4 and MBOAT7 to promote polyunsaturated phospholipid synthesis and susceptibility to ferroptosis
VV Phadnis, J Snider, V Wong, KD Vaccaro, T Kunchok, J Allen, Z Yao, ...
Biorxiv, 2022.09. 01.506096, 2022
12022
Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST
HG Sprenger, MJ Mittenbuehler, Y Sun, JG Van Vranken, S Schindler, ...
bioRxiv, 2024.04. 10.588849, 2024
2024
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability
KL Abbott, A Ali, BI Reinfeld, A Deik, S Subudhi, MD Landis, RA Hongo, ...
bioRxiv, 2023
2023
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