| Astrocytic ceramide as possible indicator of neuroinflammation NM De Wit, S Den Hoedt, P Martinez-Martinez, AJ Rozemuller, MT Mulder, ... Journal of neuroinflammation 16, 1-11, 2019 | 68 | 2019 |
| Sphingolipids in Alzheimer's disease, how can we target them? SM Crivelli, C Giovagnoni, L Visseren, AL Scheithauer, N de Wit, ... Advanced drug delivery reviews 159, 214-231, 2020 | 65 | 2020 |
| From pediatric covariate model to semiphysiological function for maturation: part II—sensitivity to physiological and physicochemical properties EHJ Krekels, TN Johnson, SM Den Hoedt, A Rostami‐Hodjegan, ... CPT: pharmacometrics & systems pharmacology 1 (10), 1-8, 2012 | 51 | 2012 |
| Altered sphingolipid balance in capillary cerebral amyloid angiopathy NM De Wit, H Snkhchyan, S Den Hoedt, D Wattimena, R De Vos, ... Journal of Alzheimer's Disease 60 (3), 795-807, 2017 | 35 | 2017 |
| Molecular mechanisms of action of M5 muscarinic acetylcholine receptor allosteric modulators AE Berizzi, PR Gentry, P Rueda, S Den Hoedt, PM Sexton, CJ Langmead, ... Molecular pharmacology 90 (4), 427-436, 2016 | 33 | 2016 |
| Variation in coronary atherosclerosis severity related to a distinct LDL (low-density lipoprotein) profile: findings from a familial hypercholesterolemia pig model A Hoogendoorn, S den Hoedt, EMJ Hartman, I Krabbendam-Peters, ... Arteriosclerosis, Thrombosis, and Vascular Biology 39 (11), 2338-2352, 2019 | 26 | 2019 |
| CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer’s disease SM Crivelli, Q Luo, JAA Stevens, C Giovagnoni, D van Kruining, G Bode, ... Alzheimer's Research & Therapy 13, 1-21, 2021 | 22 | 2021 |
| Effects of sex, age, and apolipoprotein E genotype on brain ceramides and sphingosine-1-phosphate in Alzheimer’s disease and control mice S den Hoedt, SM Crivelli, FPJ Leijten, M Losen, JAA Stevens, ... Frontiers in aging neuroscience 13, 765252, 2021 | 13 | 2021 |
| Pleiotropic effect of human ApoE4 on cerebral ceramide and saturated fatty acid levels S Den Hoedt, CIF Janssen, G Astarita, D Piomelli, FPJ Leijten, SM Crivelli, ... Journal of Alzheimer's Disease 60 (3), 769-781, 2017 | 9 | 2017 |
| Acid sphingomyelinase: No potential as a biomarker for multiple sclerosis CE Leurs, MAL Pinheiro, L Wierts, S den Hoedt, MT Mulder, AJC Eijlers, ... Multiple sclerosis and related disorders 28, 44-49, 2019 | 8 | 2019 |
| SMPD4 regulates mitotic nuclear envelope dynamics and its loss causes microcephaly and diabetes DJ Smits, R Schot, N Krusy, K Wiegmann, O Utermöhlen, MT Mulder, ... Brain 146 (8), 3528-3541, 2023 | 6 | 2023 |
| Sphingolipid metabolism governs Purkinje cell patterned degeneration in Atxn1[82Q]/+ mice FGC Blot, WHJJ Krijnen, S Den Hoedt, C Osório, JJ White, MT Mulder, ... Proceedings of the National Academy of Sciences 118 (36), e2016969118, 2021 | 6 | 2021 |
| FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer’s disease expressing APOE4 SM Crivelli, Q Luo, D van Kruining, C Giovagnoni, M Mané-Damas, ... Biomedicine & Pharmacotherapy 152, 113240, 2022 | 5 | 2022 |
| Target-site investigation for the plasma prolactin response: mechanism-based pharmacokinetic-pharmacodynamic analysis of risperidone and paliperidone in the rat S Shimizu, SM den Hoedt, V Mangas-Sanjuan, S Cristea, JK Geuer, ... Drug Metabolism and Disposition 45 (2), 152-159, 2017 | 4 | 2017 |
| Top–down modeling meets bottom–up modeling: the physiological and physicochemical basis for the ontogeny of UGT2B7-mediated drug glucuronidation. 2012 EHJ Krekels, TN Johnson, SM den Hoedt | 1 | |
| Sphingolipids in Cerebrospinal Fluid and Plasma Lipoproteins of APOE4 Homozygotes and Non-APOE4 Carriers with Mild Cognitive Impairment versus Subjective Cognitive Decline S den Hoedt, KY Dorst-Lagerwerf, HE de Vries, AJM Rozemuller, ... Journal of Alzheimer's Disease Reports, 1-16, 2023 | | 2023 |
| 5222 A distinct LDL profile to predict the risk of cardiovascular disease in familial hypercholesterolemia subjects: initial pre-clinical results A Hoogendoorn, S Den Hoedt, E Hartman, I Krabbendam-Peters, ... European Heart Journal 40 (Supplement_1), ehz746. 0071, 2019 | | 2019 |
| A distinct LDL profile to predict the risk of cardiovascular disease in familial hypercholesterolemia subjects: initial pre-clinical results A Hoogendoorn, S Den Hoedt, L van der Zee-van Vark, K Dorst, ... Atherosclerosis 287, e220, 2019 | | 2019 |
| Top-Down Modeling Meets Bottom-Up Modeling: The Physiological and Physiochemical Basis for the Ontogeny of UGT2B7-Mediated Drug Glucuronidation A Rostami-Hochaghan, A Rostami-Hodjegan, EHJ Krekels, TN Johnson, ... WCoP, 2012 | | 2012 |
