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Fiona Brown
Fiona Brown
Post Doctoral Research Fellow, The Ohio State University
Verified email at osumc.edu
Title
Cited by
Cited by
Year
Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter’s transformation
ZA Hing, JS Walker, EC Whipp, L Brinton, M Cannon, P Zhang, S Sher, ...
Nature Communications 14 (1), 97, 2023
132023
Radiant star nanoparticle prodrugs for the treatment of intracellular alveolar infections
D Das, S Srinivasan, FD Brown, FY Su, AL Burrell, JM Kollman, A Postma, ...
Polymer Chemistry 9 (16), 2134-2146, 2018
122018
Validation of protein arginine methyltransferase 5 (PRMT5) as a candidate therapeutic target in the spontaneous canine model of non-Hodgkin lymphoma
SL Sloan, KA Renaldo, M Long, JH Chung, LE Courtney, K Shilo, ...
PloS one 16 (5), e0250839, 2021
102021
PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma
SL Sloan, F Brown, M Long, C Weigel, S Koirala, JH Chung, B Pray, ...
Blood 142 (10), 887-902, 2023
72023
Targeting prmt5 to circumvent acquired ibrutinib resistance in mantle cell lymphoma
S Sloan, F Brown, JH Chung, A Prouty, E Wheeler, BK Harrington, ...
Blood 134, 4065, 2019
52019
PRMT5 inhibition drives therapeutic vulnerability to combination treatment with BCL-2 inhibition in mantle cell lymphoma
F Brown-Burke, I Hwang, S Sloan, C Hinterschied, JB Helmig-Mason, ...
Blood Advances 7 (20), 6211-6224, 2023
32023
PRMT5 Inhibition Reduces Autoinflammation in a Murine Model of Secondary Hemophagocytic Lymphohistiocytosis
P Shindiapina, R Saadey, A Yasin, C Mao, A Wandke, EH Ahmed, ...
Blood 140 (Supplement 1), 36-37, 2022
22022
PRMT5 inhibition promotes FOXO1 tumor suppressor activity to drive a pro-apoptotic program that creates vulnerability to combination treatment with venetoclax in mantle cell …
F Brown, I Hwang, S Sloan, C Hinterschied, JB Helmig-Mason, M Long, ...
Blood 138, 681, 2021
22021
PRMT5 inhibition modulates E2F1 and P53 to restore cell cycle regulation and drive DNA damage response in ibrutinib-resistant mantle cell lymphoma
S Sloan, F Brown, M Long, JB Helmig-Mason, S Beck, JH Chung, ...
Blood 138, 787, 2021
22021
PRMT5 inhibition drives therapeutic vulnerability to BCL-2 inhibition with Venetoclax and provides rationale for combination therapy in mantle cell lymphoma
F Brown, Y Zhang, C Hinterschied, A Prouty, S Sloan, JB Helmig-Mason, ...
Blood 134, 302, 2019
22019
Acquired resistance to PRMT5 inhibition in mantle cell lymphoma is associated with compensatory activation of multiple signaling pathways
M Long, S Koirala, S Sloan, F Brown, S Tallada, C Hinterschied, K Corps, ...
Blood 140 (Supplement 1), 3103-3104, 2022
12022
Constitutive PRMT5 Expression Drives Spontaneous Lymphoblastic Lymphoma In Vivo
L Villagomez, P Smith, F Yan, V Chen, S Sloan, JT Patton, M Long, ...
Blood 140 (Supplement 1), 6381-6382, 2022
2022
Dysregulation of PRMT5 in Chronic Lymphocytic Leukemia Supports Transformation to Diffuse Large B-Cell Lymphoma
E Whipp, ZA Hing, JS Walker, S Sher, CB Cempre, F Brown, C Agostinelli, ...
Blood 140 (Supplement 1), 8746-8747, 2022
2022
PRMT5 Inhibition Potentiates Anti-Tumor Immune Targeting of EBV-Driven B Cell Lymphoproliferative Disease
EH Ahmed, C Weigel, R Saadey, E Brooks, T Cash, C Mao, A Yasin, ...
Blood 140 (Supplement 1), 3116-3117, 2022
2022
PRMT5 inhibition alters mitochondrial dynamics in mantle cell lymphoma, creating vulnerability to BH3 mimetic compounds
C Hinterschied, F Brown, J Ravikrishnan, JB Helmig-Mason, K Vaddi, ...
Cancer Research 82 (12_Supplement), 1031-1031, 2022
2022
P1250: EU-SOX11CCND1: A NOVEL IMMUNOCOMPETENT MURINE MODEL OF MANTLE CELL LYMPHOMA
F Brown, S Sloan, J Helmig-Mason, C Hinterschied, M Long, WK Chan, ...
HemaSphere 6, 1135-1136, 2022
2022
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