CXCR2 antagonists for the treatment of pulmonary disease RW Chapman, JE Phillips, RW Hipkin, AK Curran, D Lundell, JS Fine Pharmacology & therapeutics 121 (1), 55-68, 2009 | 254 | 2009 |
Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for “active” disease R Peng, S Sridhar, G Tyagi, JE Phillips, R Garrido, P Harris, L Burns, ... PloS one 8 (4), e59348, 2013 | 241 | 2013 |
A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary … RW Chapman, M Minnicozzi, CS Celly, JE Phillips, TT Kung, RW Hipkin, ... Journal of Pharmacology and Experimental Therapeutics 322 (2), 486-493, 2007 | 171 | 2007 |
Assessment of Brd4 inhibition in idiopathic pulmonary fibrosis lung fibroblasts and in vivo models of lung fibrosis X Tang, R Peng, JE Phillips, J Deguzman, Y Ren, S Apparsundaram, ... The American journal of pathology 183 (2), 470-479, 2013 | 152 | 2013 |
Drug repurposing: the anthelmintics niclosamide and nitazoxanide are potent TMEM16A antagonists that fully bronchodilate airways K Miner, K Labitzke, B Liu, P Wang, K Henckels, K Gaida, R Elliott, ... Frontiers in pharmacology 10, 51, 2019 | 126 | 2019 |
Inhaled phosphodiesterase 4 (PDE4) inhibitors for inflammatory respiratory diseases JE Phillips Frontiers in Pharmacology 11, 519743, 2020 | 87 | 2020 |
Regulation of vocal fold transepithelial water fluxes KV Fisher, A Telser, JE Phillips, DB Yeates Journal of Applied Physiology 91 (3), 1401-1411, 2001 | 82 | 2001 |
C (4)-alkyl substituted furanyl cyclobutenediones as potent, orally bioavailable CXCR2 and CXCR1 receptor antagonists J Chao, AG Taveras, J Chao, C Aki, M Dwyer, Y Yu, B Purakkattle, ... Bioorganic & medicinal chemistry letters 17 (13), 3778-3783, 2007 | 65 | 2007 |
Double-stranded RNA induces molecular and inflammatory signatures that are directly relevant to COPD P Harris, S Sridhar, R Peng, JE Phillips, RG Cohn, L Burns, J Woods, ... Mucosal immunology 6 (3), 474-484, 2013 | 60 | 2013 |
Effect of inhaled roflumilast on the prevention and resolution of allergen-induced late phase airflow obstruction in Brown Norway rats RW Chapman, A House, H Jones, J Richard, C Celly, D Prelusky, P Ting, ... European journal of pharmacology 571 (2-3), 215-221, 2007 | 60 | 2007 |
Development of passive CLARITY and immunofluorescent labelling of multiple proteins in human cerebellum: understanding mechanisms of neurodegeneration in mitochondrial disease J Phillips, A Laude, R Lightowlers, CM Morris, DM Turnbull, NZ Lax Scientific reports 6 (1), 26013, 2016 | 54 | 2016 |
Antigen-induced mast cell expansion and bronchoconstriction in a mouse model of asthma S Li, M Aliyeva, N Daphtary, RA Martin, ME Poynter, SF Kostin, ... American Journal of Physiology-Lung Cellular and Molecular Physiology, 2014 | 49 | 2014 |
Inhaled efficacious dose translation from rodent to human: A retrospective analysis of clinical standards for respiratory diseases JE Phillips Pharmacology & Therapeutics 178, 141-147, 2017 | 44 | 2017 |
Bidirectional transepithelial water transport: measurement and governing mechanisms JE Phillips, LB Wong, DB Yeates Biophysical Journal 76 (2), 869-877, 1999 | 44 | 1999 |
Tachykinin NK3 and NK1 receptor activation elicits secretion from porcine airway submucosal glands JE Phillips, JA Hey, MR Corboz British journal of pharmacology 138 (1), 254-260, 2003 | 43 | 2003 |
Bleomycin induced lung fibrosis increases work of breathing in the mouse JE Phillips, R Peng, L Burns, P Harris, R Garrido, G Tyagi, JS Fine, ... Pulmonary pharmacology & therapeutics 25 (4), 281-285, 2012 | 39 | 2012 |
Three-dimensional analysis of rodent paranasal sinus cavities from X-ray computed tomography (CT) scans JE Phillips, L Ji, MA Rivelli, RW Chapman, MR Corboz Canadian Journal of Veterinary Research 73 (3), 205, 2009 | 38 | 2009 |
Pharmacology of a potent and selective inhibitor of PDE4 for inhaled administration RW Chapman, A House, J Richard, D Prelusky, J Lamca, P Wang, ... European journal of pharmacology 643 (2-3), 274-281, 2010 | 32 | 2010 |
Dry powder and nebulized aerosol inhalation of pharmaceuticals delivered to mice using a nose-only exposure system JE Phillips, X Zhang, JA Johnston JoVE (Journal of Visualized Experiments), e55454, 2017 | 20 | 2017 |
House dust mite models: will they translate clinically as a superior model of asthma? JE Phillips, R Peng, P Harris, L Burns, L Renteria, LKA Lundblad, JS Fine, ... Journal of allergy and clinical immunology 132 (1), 242-244, 2013 | 18 | 2013 |