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Hector Perez-Montoyo
Hector Perez-Montoyo
Director of Biological Research and Project Manager in Ability Pharmaceuticals, SL
Verified email at abilitypharma.com - Homepage
Title
Cited by
Cited by
Year
Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice
HP Montoyo, C Vaccaro, M Hafner, RJ Ober, W Mueller, ES Ward
Proceedings of the National Academy of Sciences 106 (8), 2788-2793, 2009
2212009
Neonatal Fc receptor blockade by Fc engineering ameliorates arthritis in a murine model
DA Patel, A Puig-Canto, DK Challa, HP Montoyo, RJ Ober, ES Ward
The Journal of Immunology 187 (2), 1015-1022, 2011
1022011
Targeting p38α increases DNA damage, chromosome instability, and the anti-tumoral response to taxanes in breast cancer cells
B Cánovas, A Igea, AA Sartori, RR Gomis, TT Paull, M Isoda, ...
Cancer cell 33 (6), 1094-1110. e8, 2018
932018
The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells
P Muñoz-Guardiola, J Casas, E Megías-Roda, S Solé, H Perez-Montoyo, ...
Autophagy 17 (6), 1349-1366, 2021
822021
Resistance to taxanes in triple-negative breast cancer associates with the dynamics of a CD49f+ tumor-initiating population
J Gómez-Miragaya, M Palafox, L Paré, G Yoldi, I Ferrer, S Vila, P Galván, ...
Stem cell reports 8 (5), 1392-1407, 2017
812017
Autoantibody depletion ameliorates disease in murine experimental autoimmune encephalomyelitis
DK Challa, U Bussmeyer, T Khan, HP Montoyo, P Bansal, RJ Ober, ...
MAbs 5 (5), 655-659, 2013
622013
Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis
DK Challa, X Wang, HP Montoyo, R Velmurugan, RJ Ober, ES Ward
MAbs 11 (5), 848-860, 2019
502019
Therapeutic potential of the new TRIB3-mediated cell autophagy anticancer drug ABTL0812 in endometrial cancer
I Felip, CP Moiola, C Megino-Luque, C Lopez-Gil, S Cabrera, ...
Gynecologic Oncology 153 (2), 425-435, 2019
372019
Therapeutic potential of autophagy modulation in cholangiocarcinoma
H Perez-Montoyo
Cells 9 (3), 614, 2020
322020
The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer
A López‐Plana, P Fernández‐Nogueira, P Muñoz‐Guardiola, ...
International Journal of Cancer 147 (4), 1163-1179, 2020
172020
The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival
N Diéguez-Martínez, S Espinosa-Gil, G Yoldi, E Megías-Roda, ...
Cellular and Molecular Life Sciences 79 (10), 524, 2022
152022
The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis
L París-Coderch, A Soriano, C Jiménez, T Erazo, P Muñoz-Guardiola, ...
Cell Death & Disease 11 (9), 773, 2020
102020
GPBP-1 inhibition and its therapeutic use
J Saus, F Revert-Ros, F Revert, C Aguado-Velasco, E López-Pascual, ...
US Patent 9,066,938, 2015
72015
Assessment of biological activity in RAW 264.7 cell line stimulated with lipopolysaccharide using dynamic laser speckle
RJ González-Peña, H Pérez-Montoyo, RA Braga, DC Viana
Applied Physics B 122, 1-8, 2016
52016
Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models
A Mancini, A Colapietro, L Cristiano, A Rossetti, V Mattei, GL Gravina, ...
Frontiers in Oncology 12, 943064, 2022
42022
The first-in-class anti-cancer agent ABTL0812 is effective in preclinical models of human endometrial cancer.
EC Colàs, N Eritja, P Muñoz-Guardiola, S Sole-Sanchez, C Moiola, I Felip, ...
Journal of Clinical Oncology 35 (15_suppl), e17070-e17070, 2017
32017
Determination of recommended phase II dose of ABTL0812, a novel regulator of Akt/mTOR axis, by pharmacokinetic-pharmacodynamic modelling
J Alfon, L Vidal, L Gaba, I Victoria, M Gil, B Laquente, M Brunet, H Colom, ...
Annals of Oncology 27, vi120, 2016
32016
RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer
M Ciscar, EM Trinidad, G Perez‐Chacon, M Alsaleem, M Jimenez, ...
EMBO Molecular Medicine 15 (4), e16715, 2023
22023
ABTL0812 enhances antitumor effect of paclitaxel and reverts chemoresistance in triple‐negative breast cancer models
E Polonio‐Alcalá, S Solé‐Sánchez, P Muñoz‐Guardiola, E Megías‐Roda, ...
Cancer Communications 42 (6), 567, 2022
22022
ABTL0812, a phase 2 clinical stage pro-autophagy anticancer drug exhibits immunomodulatory effects that modify tumor microenvironment in pancreatic cancer models
G Yoldi, P Munoz-Guardiola, E Megias, H Perez-Montoyo, ...
Cancer Research 81 (13_Supplement), 1805-1805, 2021
22021
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