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Michael A Smith
Michael A Smith
Senior Computational Biologist, Amgen
No verified email
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Year
Self-reactive IgE exacerbates interferon responses associated with autoimmunity
J Henault, JM Riggs, JL Karnell, VM Liarski, J Li, L Shirinian, L Xu, ...
Nature immunology 17 (2), 196-203, 2016
1462016
Serum glial fibrillary acidic protein: a neuromyelitis optica spectrum disorder biomarker
O Aktas, MA Smith, WA Rees, JL Bennett, D She, E Katz, BAC Cree, ...
Annals of neurology 89 (5), 895-910, 2021
922021
Hepatitis delta virus detected in salivary glands of Sjögren's syndrome patients and recapitulates a Sjögren's syndrome-like phenotype in vivo
ML Weller, MR Gardener, ZC Bogus, MA Smith, E Astorri, DG Michael, ...
Pathogens & immunity 1 (1), 12, 2016
652016
Type I interferon receptor blockade with anifrolumab corrects innate and adaptive immune perturbations of SLE
KA Casey, X Guo, MA Smith, S Wang, D Sinibaldi, MA Sanjuan, L Wang, ...
Lupus Science & Medicine 5 (1), e000286, 2018
642018
Depleting plasmacytoid dendritic cells reduces local type I interferon responses and disease activity in patients with cutaneous lupus
JL Karnell, Y Wu, N Mittereder, MA Smith, M Gunsior, L Yan, KA Casey, ...
Science translational medicine 13 (595), eabf8442, 2021
602021
Modulation of cardiometabolic disease markers by type I interferon inhibition in systemic lupus erythematosus
KA Casey, MA Smith, D Sinibaldi, NL Seto, MP Playford, X Wang, ...
Arthritis & Rheumatology 73 (3), 459-471, 2021
452021
Natural killer cell expression of Ki67 is associated with elevated serum IL-15, disease activity and nephritis in systemic lupus erythematosus
K Hudspeth, S Wang, J Wang, S Rahman, MA Smith, KA Casey, ...
Clinical & Experimental Immunology 196 (2), 226-236, 2019
312019
Disability outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder
R Marignier, JL Bennett, HJ Kim, BG Weinshenker, SJ Pittock, ...
Neurology: Neuroimmunology & Neuroinflammation 8 (3), e978, 2021
282021
SLE plasma profiling identifies unique signatures of lupus nephritis and discoid lupus
MA Smith, J Henault, JL Karnell, ML Parker, JM Riggs, D Sinibaldi, ...
Scientific reports 9 (1), 14433, 2019
222019
AQP4-IgG-seronegative patient outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder
R Marignier, SJ Pittock, F Paul, HJ Kim, JL Bennett, BG Weinshenker, ...
Multiple Sclerosis and Related Disorders 57, 103356, 2022
202022
Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus
MA Smith, CC Chiang, K Zerrouki, S Rahman, WI White, K Streicher, ...
Scientific Reports 10 (1), 4462, 2020
192020
Association between B-cell depletion and attack risk in neuromyelitis optica spectrum disorder: An exploratory analysis from N-MOmentum, a double-blind, randomised, placebo …
JL Bennett, O Aktas, WA Rees, MA Smith, M Gunsior, L Yan, D She, ...
EBioMedicine 86, 2022
122022
Serum neurofilament light chain levels at attack predict post-attack disability worsening and are mitigated by inebilizumab: analysis of four potential biomarkers in …
O Aktas, HP Hartung, MA Smith, WA Rees, K Fujihara, F Paul, R Marignier, ...
Journal of Neurology, Neurosurgery & Psychiatry 94 (9), 757-768, 2023
82023
OP0174 Alteration of mediators of vascular inflammation by anifrolumab in the phase iib muse study in sle
WI White, NL Seto, MP Playford, KA Casey, MA Smith, P Carlucci, B Yu, ...
Annals of the Rheumatic Diseases 77 (Suppl 2), 136-137, 2018
52018
Shared and distinctive transcriptomic and proteomic pathways in adult and juvenile dermatomyositis
JM Ward, M Ambatipudi, TP O'Hanlon, MA Smith, M de Los Reyes, ...
Arthritis & Rheumatology 75 (11), 2014-2026, 2023
32023
Attack adjudication in neuromyelitis optica spectrum disorder: Substantiation of criteria by magnetic resonance imaging and biomarkers in N-MOmentum
BG Weinshenker, DM Wingerchuk, AJ Green, JL Bennett, HJ Kim, ...
Multiple Sclerosis Journal 29 (8), 945-955, 2023
32023
Extent of B-cell depletion is associated with disease activity reduction in neuromyelitis optica spectrum disorder: results from the N-MOmentum study
JL Bennett, O Aktas, M Smith, WA Rees, E Katz, BAC Cree
MULTIPLE SCLEROSIS JOURNAL 27 (2_ SUPPL), 151-152, 2021
22021
(DAM04) Serum Glial Fibrillary Acidic Protein Is Elevated in a Subset of Neuromyelitis Optica Patients and Associated with Increased Risk of Attacks.
HP Hartung, O Aktas, MA Smith, W Rees, K Fujihara, F Paul, R Marignier, ...
International Journal of MS Care 22, 2020
22020
Inebilizumab reduces neuromyelitis optica spectrum disorder risk independent of FCGR3A polymorphism
HJ Kim, O Aktas, KR Patterson, S Korff, A Kunchok, JL Bennett, ...
Annals of Clinical and Translational Neurology 10 (12), 2413-2420, 2023
12023
Inebilizumab Reduces Attack Risk Independent of Low Affinity IgG Fc Region Receptor III-A Gene Polymorphisms in Neuromyelitis Optica Spectrum Disorder (P13-5.015)
B Weinshenker, J Bennett, B Cree, F Paul, HJ Kim, HP Hartung, ...
Neurology 100 (17 Supplement 2), 2023
12023
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