| Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell–and patient-derived tumor organoids L Huang, A Holtzinger, I Jagan, M BeGora, I Lohse, N Ngai, C Nostro, ... Nature medicine 21 (11), 1364-1371, 2015 | 767 | 2015 |
| Cancer stem cells, the epithelial to mesenchymal transition (EMT) and radioresistance: potential role of hypoxia DT Marie-Egyptienne, I Lohse, RP Hill Cancer letters 341 (1), 63-72, 2013 | 271 | 2013 |
| Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies H Yang, S Kurtenbach, Y Guo, I Lohse, MA Durante, J Li, Z Li, H Al-Ali, ... Blood, The Journal of the American Society of Hematology 131 (3), 328-341, 2018 | 170 | 2018 |
| Targeting of metastasis-promoting tumor-associated fibroblasts and modulation of pancreatic tumor-associated stroma with a carboxymethylcellulose-docetaxel nanoparticle MJ Ernsting, B Hoang, I Lohse, E Undzys, P Cao, T Do, B Gill, M Pintilie, ... Journal of Controlled Release 206, 122-130, 2015 | 126 | 2015 |
| Effect of high dose per pulse flattening filter-free beams on cancer cell survival I Lohse, S Lang, J Hrbacek, S Scheidegger, S Bodis, NS Macedo, J Feng, ... Radiotherapy and Oncology 101 (1), 226-232, 2011 | 125 | 2011 |
| Quantitative proteomic analysis of serum exosomes from patients with locally advanced pancreatic cancer undergoing chemoradiotherapy M An, I Lohse, Z Tan, J Zhu, J Wu, H Kurapati, MA Morgan, TS Lawrence, ... Journal of proteome research 16 (4), 1763-1772, 2017 | 111 | 2017 |
| mRNA-to-protein translation in hypoxia NT Chee, I Lohse, SP Brothers Molecular cancer 18 (1), 49, 2019 | 99 | 2019 |
| BRCA1 and BRCA2 mutations sensitize to chemotherapy in patient-derived pancreatic cancer xenografts I Lohse, A Borgida, P Cao, M Cheung, M Pintilie, T Bianco, S Holter, ... British journal of cancer 113 (3), 425-432, 2015 | 87 | 2015 |
| Pathogenesis and treatment of pancreatic cancer related pain I Lohse, SP Brothers Anticancer research 40 (4), 1789-1796, 2020 | 72 | 2020 |
| Assessment of hypoxia in the stroma of patient-derived pancreatic tumor xenografts I Lohse, C Lourenco, E Ibrahimov, M Pintilie, MS Tsao, DW Hedley Cancers 6 (1), 459-471, 2014 | 69 | 2014 |
| Unraveling biophysical interactions of radiation pneumonitis in non-small-cell lung cancer via Bayesian network analysis Y Luo, I El Naqa, DL McShan, D Ray, I Lohse, MM Matuszak, D Owen, ... Radiotherapy and Oncology 123 (1), 85-92, 2017 | 64 | 2017 |
| Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study RT Swords, D Azzam, H Al-Ali, I Lohse, CH Volmar, JM Watts, A Perez, ... Leukemia Research 64, 34-41, 2018 | 59 | 2018 |
| Sexual dimorphism in the 3xTg-AD mouse model and its impact on pre-clinical research JL Dennison, NR Ricciardi, I Lohse, CH Volmar, C Wahlestedt Journal of Alzheimer's disease 80 (1), 41-52, 2021 | 58 | 2021 |
| Activity of the novel polo-like kinase 4 inhibitor CFI-400945 in pancreatic cancer patient-derived xenografts I Lohse, J Mason, PC Mary, M Pintilie, M Bray, DW Hedley Oncotarget 8 (2), 3064, 2016 | 51 | 2016 |
| Targeting hypoxic microenvironment of pancreatic xenografts with the hypoxia-activated prodrug TH-302 I Lohse, J Rasowski, P Cao, M Pintilie, T Do, MS Tsao, RP Hill, ... Oncotarget 7 (23), 33571, 2016 | 50 | 2016 |
| Expansion of circulating tumor cells from patients with locally advanced pancreatic cancer enable patient derived xenografts and functional studies for personalized medicine L Rivera-Báez, I Lohse, E Lin, S Raghavan, S Owen, R Harouaka, ... Cancers 12 (4), 1011, 2020 | 44 | 2020 |
| Fbxw7 deletion accelerates KrasG12D-Driven pancreatic tumorigenesis via Yap accumulation Q Zhang, Y Zhang, JD Parsels, I Lohse, TS Lawrence, MP di Magliano, ... Neoplasia 18 (11), 666-673, 2016 | 43 | 2016 |
| Ipilimumab/nivolumab therapy in patients with metastatic pancreatic or biliary cancer with homologous recombination deficiency pathogenic germline variants G Terrero, J Datta, J Dennison, DA Sussman, I Lohse, NB Merchant, ... JAMA oncology 8 (6), 938-940, 2022 | 38 | 2022 |
| The CPT1C 5′ UTR contains a repressing upstream open reading frame that is regulated by cellular energy availability and AMPK I Lohse, P Reilly, K Zaugg PLoS one 6 (9), e21486, 2011 | 30 | 2011 |
| BET bromodomain inhibitors which permit treg function enable a combinatorial strategy to suppress GVHD in pre-clinical allogeneic HSCT SN Copsel, CO Lightbourn, H Barreras, I Lohse, D Wolf, CS Bader, ... Frontiers in immunology 9, 3104, 2019 | 26 | 2019 |
